Zobrazeno 1 - 10
of 79
pro vyhledávání: '"miR, microRNA"'
Targeted chitosan nanobubbles as a strategy to down-regulate microRNA-17 into B-cell lymphoma models
Autor:
Sara Capolla, Monica Argenziano, Sara Bozzer, Tiziana D’Agaro, Tamara Bittolo, Luigina De Leo, Tarcisio Not, Davide Busato, Michele Dal Bo, Giuseppe Toffoli, Roberta Cavalli, Valter Gattei, Riccardo Bomben, Paolo Macor
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMicroRNAs represent interesting targets for new therapies because their altered expression influences tumor development and progression. miR-17 is a prototype of onco-miRNA, known to be overexpressed in B-cell non-Hodgkin lymphoma (B-NHL)
Externí odkaz:
https://doaj.org/article/700fa76819c64673b3c87d0dc34aa22c
Autor:
A.E. Abaturov, V.L. Babуch
Publikováno v:
Zdorovʹe Rebenka, Vol 16, Iss 8, Pp 546-553 (2021)
The scientific review presents the mechanisms of action of intranuclear miRNAs, namely the influence of intranuclear miRNAs on transcription. To write the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar
Externí odkaz:
https://doaj.org/article/912194bf16f74127b211b98878c1a340
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 23, Iss 8, Pp 1045-1052 (2020)
Objective(s): MicroRNAs (miRs) are a class of small non-coding RNAs which are associated with tumor growth and progression. In the present study, we assessed the expression of selected miRs in malignant, benign, and adjacent normal breast tissues. Ma
Externí odkaz:
https://doaj.org/article/a8615cb9dd0049ef91a3fbe1a2205e8a
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Almost all nucleated cells secrete extracellular vesicles (EVs) that are heterogeneous spheroid patterned or round shape particles ranging from 30 to 200 nm in size. Recent preclinical and clinical studies have shown that endothelial progenitor cell-
Externí odkaz:
https://doaj.org/article/2d69d40edca64419bda8dc5f56e9ae38
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/97d53297a5fd4fd8ab188416f0aa650e
Autor:
Banrida Wahlang, Monika Thapa, Michael L. Merchant, Jian Jin, Sudhir Srivastava, Josiah E. Hardesty, Russell A. Prough, Shesh N. Rai, Matthew C. Cave, Kimberly Z. Head
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3806-3819 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Dioxin-like molecules have been associated with endocrine disruption and liver disease. To better understand aryl hydrocarbon receptor (AHR) biology, metabolic phenotyping and liver proteomics were performed in mice following ligand-activation or who
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 887-897 (2021)
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 9, Pp 887-897 (2021)
In recent years, increasing evidence indicates the significant roles of circRNAs in carcinogenesis. However, their roles in lung cancer remain largely unclear. We profiled the circRNA expression in 10 paired non-small cell lung cancer (NSCLC) and adj
Akademický článek
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Autor:
Hamza Hanieh, Abdullah M. Alzahrani
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 28, Iss 12, Pp 1605-1615 (2020)
Saudi Pharmaceutical Journal, Vol 28, Iss 12, Pp 1605-1615 (2020)
Graphical abstract
Multiple sclerosis (MS) is an autoimmune disease that involves demyelination of axons in the central nervous system (CNS) and affects patients worldwide. It has been demonstrated that ligand-activated aryl hydrocarbon receptor
Multiple sclerosis (MS) is an autoimmune disease that involves demyelination of axons in the central nervous system (CNS) and affects patients worldwide. It has been demonstrated that ligand-activated aryl hydrocarbon receptor
Autor:
Dushyantha Jayaweera, Aisha Khan, Xian Ming Chu, Huilan Wang, Michael A. Bellio, Andrea da Fonseca Ferreira, Chunming Dong, Lukun Zhang, Qianhuan Zhang, Joshua M. Hare, Jianqing Wei, Liyong Wang
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • EVs derived from young, but not aged, MSCs rejuvenate senescent EPCs in vitro, recapitulating the effect of MSC transplantation. • Aged MSCs can be genetically modified to produce tailored EVs with increased EPC
Highlights • EVs derived from young, but not aged, MSCs rejuvenate senescent EPCs in vitro, recapitulating the effect of MSC transplantation. • Aged MSCs can be genetically modified to produce tailored EVs with increased EPC