Zobrazeno 1 - 10
of 1 399
pro vyhledávání: '"methylcobalamin"'
Publikováno v:
Bulletin of the National Research Centre, Vol 48, Iss 1, Pp 1-3 (2024)
Abstract Background Thrombophilia is characterised by an abnormality of blood coagulation that increases thrombosis. Homocystinuria encompasses a group of disorders marked by increased levels of homocysteine and other amino acids detectable in the bl
Externí odkaz:
https://doaj.org/article/8339092a46a845ce8468ea41ad203970
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background The methylcobalamin deficiency G (cblG) disorder, a rare autosomal recessive disease, is attributed to mutations in the MTR gene, resulting in heightened homocysteine levels and reduced methionine and megaloblastic anemia levels.
Externí odkaz:
https://doaj.org/article/d6cb9edc9dfd4a1fa143a9169ebaf92c
Autor:
Tudor Spataru
Publikováno v:
Reactions, Vol 5, Iss 1, Pp 20-76 (2024)
For decades, the comparison of experimental data with theoretical results in studying the biochemistry of vitamin B12 has been very confusing. While the methylcobalamin cofactor-dependent Methionine Synthase process can undergo unlimited turnovers, a
Externí odkaz:
https://doaj.org/article/9a64bfa50353472e91205f36d7ff568e
Publikováno v:
Pharmacogenomics and Personalized Medicine, Vol Volume 16, Pp 895-900 (2023)
Craig Brown,1,* Jianhua Wang,2,* Hong Jiang,3,* Merrill F Elias4,* 1Department of Ophthalmology, College of Medicine, University of Arkansas for Medical Sciences, Fayetteville, AR, USA; 2Bascom Palmer Eye Institute, Miller School of M
Externí odkaz:
https://doaj.org/article/53f220dba3884017a110ab4494efbc88
PM2.5 induced neurotoxicity through unbalancing vitamin B12 metabolism by gut microbiota disturbance
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTFine particulate matter (PM2.5) in the atmosphere is easily accompanied by toxic and harmful substances, causing serious harm to human health, including cognitive impairment. Vitamin B12 (VitB12) is an essential micronutrient that is synthesi
Externí odkaz:
https://doaj.org/article/f6be64e29c82486a983b32ee6921ce69
Autor:
Tudor Spataru
Publikováno v:
Reactions, Vol 4, Iss 2, Pp 274-285 (2023)
The Methionine Synthase process, in principle, can take an unlimited number of turnovers in the presence of the AdoMet substrate. In the absence of this substrate, the Methionine Synthase process lasts only about 2000 turnovers. During 2000 turnovers
Externí odkaz:
https://doaj.org/article/4a7bd71f1b89411e80eb2c56f427eb4e
Publikováno v:
Journal of Pain Research, Vol Volume 16, Pp 1267-1284 (2023)
Gang Xu,1 Weizhen Tang,1 Chaosheng Zhou,1 Jie Xu,1 Chao Cheng,1 Weiwei Gong,2,3 Shihong Dong,2 Yu Zhang1 1Department of Rehabilitation Medicine, Affiliated Tenth People’s Hospital of Tongji University, Shanghai Tenth People’s Hospital, Shanghai,
Externí odkaz:
https://doaj.org/article/3831375cb36a487dba9448a5baca6fbd
Autor:
Evgeny Pokushalov, Andrey Ponomarenko, Sevda Bayramova, Claire Garcia, Inessa Pak, Evgenya Shrainer, Marina Ermolaeva, Dmitry Kudlay, Michael Johnson, Richard Miller
Publikováno v:
Nutrients, Vol 16, Iss 11, p 1550 (2024)
Exploring the link between genetic polymorphisms in folate metabolism genes (MTHFR, MTR, and MTRR) and cardiovascular disease (CVD), this study evaluates the effect of B vitamin supplements (methylfolate, pyridoxal-5′-phosphate, and methylcobalamin
Externí odkaz:
https://doaj.org/article/48cf6e7342b4421da5da37a7437a74ee
Autor:
Faeze Gharibpoor, Banafsheh Ghavidel-Parsa, Nazila Sattari, Ali Bidari, Fatemeh Nejatifar, Ali Montazeri
Publikováno v:
BMC Rheumatology, Vol 6, Iss 1, Pp 1-8 (2022)
Abstract Background Fibromyalgia (FM) as a prototypical nociplastic pain condition displays a difficult therapeutic situation in many cases. Given the promising data on the effect of vitamin B12 in improving pain and cognitive functions in various no
Externí odkaz:
https://doaj.org/article/6625578e0fbf44b3855bb71da9e748a7
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3217 (2023)
Methylmalonic aciduria and homocystinuria type C protein (MMACHC) is required by the body to metabolize cobalamin (Cbl). Due to its complex structure and cofactor forms, Cbl passes through an extensive series of absorptive and processing steps before
Externí odkaz:
https://doaj.org/article/efb193cde7d946cbaba58774f63f566e