Comparison of bisulfite pyrosequencing and methylation-specific qPCR for methylation assessment

Autor: Alberto Fernández-Villar, Mar Rodríguez-Girondo, Virginia Leiro-Fernández, Loretta De Chiara, Diana Valverde, María Isabel Botana-Rial

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 9242, p 9242 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 23
International Journal of Molecular Sciences, 21(23). MDPI
Investigo. Repositorio Institucional de la Universidade de Vigo
Universidade de Vigo (UVigo)

Different methodological approaches are available to assess DNA methylation biomarkers. In this study, we evaluated two sodium bisulfite conversion-dependent methods, namely pyrosequencing and methylation-specific qPCR (MS-qPCR), with the aim of meas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75565a0dfa201ed739ac7908686b831e
https://hdl.handle.net/1887/3185155

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Skewed X-Chromosome Inactivation in Women Affected by Alzheimers Disease

Autor: Elka Stefanova, Vesna Mandusic, Ana Bozovic, Biljana Spremo-Potparević, Andrea Čabarkapa, Lada Zivkovic, Radoslav Davidovic, Vladan Bajic

Publikováno v: Journal of Alzheimers Disease

X-chromosome instability has been a long established feature in Alzheimer's disease (AD). Premature centromere division and aneuploidy of the X-chromosome has been found in peripheral blood lymphocytes and neuronal tissue in female AD patients. Inter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15531be3543dc0b41b97441584570433
https://vinar.vin.bg.ac.rs/handle/123456789/314

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