Zobrazeno 1 - 10
of 16
pro vyhledávání: '"methods [Thrombolytic Therapy]"'
Autor:
Anke Wouters, Lauranne Scheldeman, Hannelore Liessens, Patrick Dupont, Florent Boutitie, Bastian Cheng, Martin Ebinger, Matthias Endres, Jochen B. Fiebach, Christian Gerloff, Keith W. Muir, Norbert Nighoghossian, Salvador Pedraza, Claus Z. Simonsen, Vincent Thijs, Götz Thomalla, Robin Lemmens
Publikováno v:
European Journal of Neurology
European Journal of Neurology, 2022, 30 (3), pp.641-647. ⟨10.1111/ene.15629⟩
European journal of neurology 30(3), 641-647 (2022). doi:10.1111/ene.15629
Wouters, A, Scheldeman, L, Liessens, H, Dupont, P, Boutitie, F, Cheng, B, Ebinger, M, Endres, M, Fiebach, J B, Gerloff, C, Muir, K W, Nighoghossian, N, Pedraza, S, Simonsen, C Z, Thijs, V, Thomalla, G & Lemmens, R 2023, ' Sex differences in imaging and clinical characteristics of patients from the WAKE-UP trial ', European Journal of Neurology, vol. 30, no. 3, pp. 641-647 . https://doi.org/10.1111/ene.15629
European Journal of Neurology, 2022, 30 (3), pp.641-647. ⟨10.1111/ene.15629⟩
European journal of neurology 30(3), 641-647 (2022). doi:10.1111/ene.15629
Wouters, A, Scheldeman, L, Liessens, H, Dupont, P, Boutitie, F, Cheng, B, Ebinger, M, Endres, M, Fiebach, J B, Gerloff, C, Muir, K W, Nighoghossian, N, Pedraza, S, Simonsen, C Z, Thijs, V, Thomalla, G & Lemmens, R 2023, ' Sex differences in imaging and clinical characteristics of patients from the WAKE-UP trial ', European Journal of Neurology, vol. 30, no. 3, pp. 641-647 . https://doi.org/10.1111/ene.15629
BACKGROUND AND PURPOSE: Sex-based differences in acute ischemic stroke are a well-known phenomenon. We aimed to explore these differences between women and men in the Efficacy and Safety of MRI-Based Thrombolysis in Wake-Up Stroke (WAKE-UP) trial. ME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6fd44d43fd4280ca4fc48780b5dd0c
https://lirias.kuleuven.be/handle/20.500.12942/706971
https://lirias.kuleuven.be/handle/20.500.12942/706971
Autor:
Salvador Pedraza, Christian Gerloff, Jochen B. Fiebach, Robin Lemmens, Eckhard Schlemm, Keith W. Muir, Alina Königsberg, Josep Puig, Matthias Endres, Martin Ebinger, Hans O. Pinnschmidt, Florent Boutitie, Claus Z Simonsen, Vincent Thijs, Götz Thomalla, Jens Fiehler, Anke Wouters, Bastian Cheng, Ivana Galinovic
Publikováno v:
International journal of stroke 17(3), 323-330 (2022). doi:10.1177/17474930211059608
Cheng, B, Pinnschmidt, H, Königsberg, A, Schlemm, E, Boutitie, F, Ebinger, M, Endres, M, Fiebach, J B, Fiehler, J, Galinovic, I, Lemmens, R, Muir, K W, Pedraza, S, Puig, J, Simonsen, C Z, Thijs, V, Wouters, A, Gerloff, C & Thomalla, G 2022, ' Estimating nocturnal stroke onset times by magnetic resonance imaging in the WAKE-UP trial ', International Journal of Stroke, vol. 17, no. 3, pp. 323-330 . https://doi.org/10.1177/17474930211059608
Cheng, B, Pinnschmidt, H, Königsberg, A, Schlemm, E, Boutitie, F, Ebinger, M, Endres, M, Fiebach, J B, Fiehler, J, Galinovic, I, Lemmens, R, Muir, K W, Pedraza, S, Puig, J, Simonsen, C Z, Thijs, V, Wouters, A, Gerloff, C & Thomalla, G 2022, ' Estimating nocturnal stroke onset times by magnetic resonance imaging in the WAKE-UP trial ', International Journal of Stroke, vol. 17, no. 3, pp. 323-330 . https://doi.org/10.1177/17474930211059608
Background Fluid-attenuated inversion recovery (FLAIR) sequences have gained a role to guide treatment of patients with unknown time of stroke symptom onset. Evolution of signal intensities in FLAIR is associated with time since stroke onset with con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6201f19bd03b378a9d333f772c64f3
https://doi.org/10.1177/17474930211059608
https://doi.org/10.1177/17474930211059608
Autor:
Alexander Konnopka, Louisa-Kristin Muntendorf, Jochen B. Fiebach, Norbert Nighoghossian, Keith W. Muir, Matthias Endres, Hans-Helmut König, Florent Boutitie, Vincent Thijs, Claus Z Simonsen, Götz Thomalla, Salvador Pedraza, Christian Gerloff, Robin Lemmens, Martin Ebinger
Publikováno v:
Value in health 24(11), 1620-1627 (2021). doi:10.1016/j.jval.2021.05.005
Value in Health
Value in Health, 2021, 24 (11), pp.1620-1627. ⟨10.1016/j.jval.2021.05.005⟩
Muntendorf, L K, Konnopka, A, König, H H, Boutitie, F, Ebinger, M, Endres, M, Fiebach, J B, Thijs, V, Lemmens, R, Muir, K W, Nighoghossian, N, Pedraza, S, Simonsen, C Z, Gerloff, C & Thomalla, G 2021, ' Cost-Effectiveness of Magnetic Resonance Imaging-Guided Thrombolysis for Patients With Stroke With Unknown Time of Onset ', Value in Health, vol. 24, no. 11, pp. 1620-1627 . https://doi.org/10.1016/j.jval.2021.05.005
Value in Health
Value in Health, 2021, 24 (11), pp.1620-1627. ⟨10.1016/j.jval.2021.05.005⟩
Muntendorf, L K, Konnopka, A, König, H H, Boutitie, F, Ebinger, M, Endres, M, Fiebach, J B, Thijs, V, Lemmens, R, Muir, K W, Nighoghossian, N, Pedraza, S, Simonsen, C Z, Gerloff, C & Thomalla, G 2021, ' Cost-Effectiveness of Magnetic Resonance Imaging-Guided Thrombolysis for Patients With Stroke With Unknown Time of Onset ', Value in Health, vol. 24, no. 11, pp. 1620-1627 . https://doi.org/10.1016/j.jval.2021.05.005
International audience; OBJECTIVES: Patients waking up with stroke symptoms are often excluded from intravenous thrombolysis with alteplase (IV-tpa). The WAKE-UP trial, a European multicenter randomized controlled trial, proved the clinical effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b489e656437ec5d84831e974e29fc65e
https://doi.org/10.1016/j.jval.2021.05.005
https://doi.org/10.1016/j.jval.2021.05.005
Autor:
Jessica L. Rohmann, Marco Piccininni, Martin Ebinger, Matthias Wendt, Joachim E. Weber, Eugen Schwabauer, Frederik Geisler, Erik Freitag, Peter Harmel, Irina Lorenz‐Meyer, Ira Rohrpasser‐Napierkowski, Christian H. Nolte, Darius G. Nabavi, Ingo Schmehl, Axel Ekkernkamp, Matthias Endres, Heinrich J. Audebert
Publikováno v:
Annals of neurology 93(1), 50-63 (2023). doi:10.1002/ana.26541
To determine the effect of additional mobile stroke unit (MSU) dispatch on functional outcomes among the full spectrum of stroke patients, regardless of subtype or potential contraindications to reperfusion therapies.We used data from the nonrandomiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98822fb16dea332de8382cdd3b31d9c0
https://pubmed.ncbi.nlm.nih.gov/36309933
https://pubmed.ncbi.nlm.nih.gov/36309933
Autor:
Eckhard Schlemm, Märit Jensen, Amy Kuceyeski, Keith Jamison, Thies Ingwersen, Carola Mayer, Alina Königsberg, Florent Boutitie, Martin Ebinger, Matthias Endres, Jochen B. Fiebach, Jens Fiehler, Ivana Galinovic, Robin Lemmens, Keith W. Muir, Norbert Nighoghossian, Salvador Pedraza, Josep Puig, Claus Z. Simonsen, Vincent Thijs, Anke Wouters, Christian Gerloff, Götz Thomalla, Bastian Cheng
Publikováno v:
Human brain mapping 43(16), 5053-5065 (2022). doi:10.1002/hbm.26073
Schlemm, E, Jensen, M, Kuceyeski, A, Jamison, K, Ingwersen, T, Mayer, C, Königsberg, A, Boutitie, F, Ebinger, M, Endres, M, Fiebach, J B, Fiehler, J, Galinovic, I, Lemmens, R, Muir, K W, Nighoghossian, N, Pedraza, S, Puig, J, Simonsen, C Z, Thijs, V, Wouters, A, Gerloff, C, Thomalla, G & Cheng, B 2022, ' Early effect of thrombolysis on structural brain network organisation after anterior-circulation stroke in the randomized WAKE-UP trial ', Human Brain Mapping, vol. 43, no. 16, pp. 5053-5065 . https://doi.org/10.1002/hbm.26073
Human Brain Mapping
Human Brain Mapping, 2022, 43 (16), pp.5053--5065. ⟨10.1002/hbm.26073⟩
Schlemm, E, Jensen, M, Kuceyeski, A, Jamison, K, Ingwersen, T, Mayer, C, Königsberg, A, Boutitie, F, Ebinger, M, Endres, M, Fiebach, J B, Fiehler, J, Galinovic, I, Lemmens, R, Muir, K W, Nighoghossian, N, Pedraza, S, Puig, J, Simonsen, C Z, Thijs, V, Wouters, A, Gerloff, C, Thomalla, G & Cheng, B 2022, ' Early effect of thrombolysis on structural brain network organisation after anterior-circulation stroke in the randomized WAKE-UP trial ', Human Brain Mapping, vol. 43, no. 16, pp. 5053-5065 . https://doi.org/10.1002/hbm.26073
Human Brain Mapping
Human Brain Mapping, 2022, 43 (16), pp.5053--5065. ⟨10.1002/hbm.26073⟩
The symptoms of acute ischemic stroke can be attributed to disruption of the brain network architecture. Systemic thrombolysis is an effective treatment that preserves structural connectivity in the first days after the event. Its effect on the evolu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a481fa01f882bed7d933d8a490d890
Autor:
Norbert Nighoghossian, Jan Vynckier, Josep Puig, Vincent Thijs, Claus Z Simonsen, Tim Bastian Braemswig, Götz Thomalla, Märit Jensen, Florent Boutitie, Ivana Galinovic, Christian H. Nolte, Christian Gerloff, Bastian Cheng, Martin Ebinger, Keith W. Muir, Jens Fiehler, Salvador Pedraza, Robin Lemmens, Matthias Endres, Jochen B. Fiebach, Ludwig Schlemm, Wake-Up investigators, Tae-Hee Cho
Publikováno v:
Schlemm, L, Braemswig, T B, Boutitie, F, Vynckier, J, Jensen, M, Galinovic, I, Simonsen, C Z, Cheng, B, Cho, T H, Fiehler, J, Puig, J, Thijs, V, Fiebach, J, Muir, K, Nighoghossian, N, Ebinger, M, Pedraza, S, Thomalla, G, Gerloff, C, Endres, M, Lemmens, R, Nolte, C H & WAKE-UP investigators 2022, ' Cerebral Microbleeds and Treatment Effect of Intravenous Thrombolysis in Acute Stroke : An Analysis of the WAKE-UP Randomized Clinical Trial ', Neurology, vol. 98, no. 3, pp. E302-E314 . https://doi.org/10.1212/WNL.0000000000013055
Neurology 98(3), e302-e314 (2022). doi:10.1212/WNL.0000000000013055
Neurology
Neurology, 2021, ⟨10.1212/wnl.0000000000013055⟩
Neurology 98(3), e302-e314 (2022). doi:10.1212/WNL.0000000000013055
Neurology
Neurology, 2021, ⟨10.1212/wnl.0000000000013055⟩
Background and ObjectivesCerebral microbleeds (CMBs) are common in patients with acute ischemic stroke and are associated with increased risk of intracerebral hemorrhage (ICH) after intravenous thrombolysis. Whether CMBs modify the treatment effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b268c3ea898b04f185977bef624c95a1
https://pure.au.dk/portal/da/publications/cerebral-microbleeds-and-treatment-effect-of-intravenous-thrombolysis-in-acute-stroke(b681d948-591c-4ebe-9b50-b220178dd847).html
https://pure.au.dk/portal/da/publications/cerebral-microbleeds-and-treatment-effect-of-intravenous-thrombolysis-in-acute-stroke(b681d948-591c-4ebe-9b50-b220178dd847).html
Autor:
Anna Kufner, Huma Fatima Ali, Martin Ebinger, Jochen B Fiebach, David S Liebeskind, Matthias Endres, Bob Siegerink, VISTA-Endovascular Collaborators
Publikováno v:
PLoS ONE
PLOS ONE 16(5), e0251888-(2021). doi:10.1371/journal.pone.0251888
PLoS ONE, Vol 16, Iss 5, p e0251888 (2021)
PLOS ONE 16(5), e0251888-(2021). doi:10.1371/journal.pone.0251888
PLoS ONE, Vol 16, Iss 5, p e0251888 (2021)
Background: The smoking-paradox of a better outcome in ischemic stroke patients who smoke may be due to increased efficacy of thrombolysis. We investigated the effect of smoking on outcome following endovascular therapy (EVT) with mechanical thrombec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5919dddcb2d671612a766578aa3c65f8
http://europepmc.org/articles/PMC8136663
http://europepmc.org/articles/PMC8136663
Autor:
Claus Z Simonsen, Ángel Chamorro, Salvador Pedraza, Vincent Thijs, Götz Thomalla, Martin Ebinger, Keith W. Muir, Florent Boutitie, Armin Schneider, Anke Wouters, Bastian Cheng, Lauranne Scheldeman, Erich Bernd Ringelstein, Matthias Endres, Jochen B. Fiebach, Christian Gerloff, Soren Christensen, Rico Laage, Norbert Nighoghossian, Patrick Dupont, Martin Grond, Robin Lemmens
Publikováno v:
Stroke
Stroke, American Heart Association, 2021, 52 (7), pp.2338-2346. ⟨10.1161/strokeaha.120.033071⟩
Stroke, 2021, 52 (7), pp.2338-2346. ⟨10.1161/strokeaha.120.033071⟩
Stroke 52(7), 2338-2346 (2021). doi:10.1161/STROKEAHA.120.033071
Scheldeman, L, Wouters, A, Dupont, P, Christensen, S, Boutitie, F, Cheng, B, Ebinger, M, Endres, M, Fiebach, J B, Gerloff, C, Muir, K W, Nighoghossian, N, Pedraza, S, Simonsen, C Z, Ringelstein, E B, Chamorro, A, Grond, M, Laage, R, Schneider, A, Thomalla, G, Thijs, V & Lemmens, R 2021, ' Reversible Edema in the Penumbra Correlates With Severity of Hypoperfusion ', Stroke, vol. 52, no. 7, pp. 2338-2346 . https://doi.org/10.1161/STROKEAHA.120.033071
Stroke, American Heart Association, 2021, 52 (7), pp.2338-2346. ⟨10.1161/strokeaha.120.033071⟩
Stroke, 2021, 52 (7), pp.2338-2346. ⟨10.1161/strokeaha.120.033071⟩
Stroke 52(7), 2338-2346 (2021). doi:10.1161/STROKEAHA.120.033071
Scheldeman, L, Wouters, A, Dupont, P, Christensen, S, Boutitie, F, Cheng, B, Ebinger, M, Endres, M, Fiebach, J B, Gerloff, C, Muir, K W, Nighoghossian, N, Pedraza, S, Simonsen, C Z, Ringelstein, E B, Chamorro, A, Grond, M, Laage, R, Schneider, A, Thomalla, G, Thijs, V & Lemmens, R 2021, ' Reversible Edema in the Penumbra Correlates With Severity of Hypoperfusion ', Stroke, vol. 52, no. 7, pp. 2338-2346 . https://doi.org/10.1161/STROKEAHA.120.033071
Background and Purpose: We aimed to investigate fluid-attenuated inversion recovery changes in the penumbra. Methods: We determined core and perfusion lesions in subjects from the WAKE-UP trial (Efficacy and Safety of MRI-Based Thrombolysis in Wake-U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805a46fd23bab5db5bfd46016bcc7abf
https://www.hal.inserm.fr/inserm-03452102/document
https://www.hal.inserm.fr/inserm-03452102/document
Autor:
Keith W. Muir, Martin Ebinger, Christian Gerloff, Thies Ingwersen, Salvador Pedraza, Alina Königsberg, Claus Z Simonsen, Götz Thomalla, Josep Puig, Eckhard Schlemm, Jochen B. Fiebach, Jens Fiehler, Anke Wouters, Bastian Cheng, Vincent Thijs, Ivana Galinovic, Matthias Endres, Florent Boutitie, Robin Lemmens, Norbert Nighoghossian
Publikováno v:
Nature Communications 12(1), 2590 (2021). doi:10.1038/s41467-021-22786-w
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2590. ⟨10.1038/s41467-021-22786-w⟩
Nature Communications, 2021, 12 (1), pp.2590. ⟨10.1038/s41467-021-22786-w⟩
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Schlemm, E, Ingwersen, T, Königsberg, A, Boutitie, F, Ebinger, M, Endres, M, Fiebach, J B, Fiehler, J, Galinovic, I, Lemmens, R, Muir, K W, Nighoghossian, N, Pedraza, S, Puig, J, Simonsen, C Z, Thijs, V, Wouters, A, Gerloff, C, Thomalla, G & Cheng, B 2021, ' Preserved structural connectivity mediates the clinical effect of thrombolysis in patients with anterior-circulation stroke ', Nature Communications, vol. 12, no. 1, 2590 . https://doi.org/10.1038/s41467-021-22786-w
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2590. ⟨10.1038/s41467-021-22786-w⟩
Nature Communications, 2021, 12 (1), pp.2590. ⟨10.1038/s41467-021-22786-w⟩
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Schlemm, E, Ingwersen, T, Königsberg, A, Boutitie, F, Ebinger, M, Endres, M, Fiebach, J B, Fiehler, J, Galinovic, I, Lemmens, R, Muir, K W, Nighoghossian, N, Pedraza, S, Puig, J, Simonsen, C Z, Thijs, V, Wouters, A, Gerloff, C, Thomalla, G & Cheng, B 2021, ' Preserved structural connectivity mediates the clinical effect of thrombolysis in patients with anterior-circulation stroke ', Nature Communications, vol. 12, no. 1, 2590 . https://doi.org/10.1038/s41467-021-22786-w
Thrombolysis with recombinant tissue plasminogen activator in acute ischemic stroke aims to restore compromised blood flow and prevent further neuronal damage. Despite the proven clinical efficacy of this treatment, little is known about the short-te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4157e758454a7f30cb973ccad7559ebd
https://pubmed.ncbi.nlm.nih.gov/33972513
https://pubmed.ncbi.nlm.nih.gov/33972513
Autor:
Matthias Endres, Jochen B. Fiebach, Anke Wouters, Bastian Cheng, Soren Christensen, Robin Lemmens, Christian Gerloff, Patrick Dupont, Keith W. Muir, Martin Ebinger, Salvador Pedraza, Florent Boutitie, Claus Z Simonsen, Götz Thomalla, Norbert Nighoghossian, Vincent Thijs, Lauranne Scheldeman
Publikováno v:
Annals of neurology 87(6), 931-938 (2020). doi:10.1002/ana.25730
Annals of Neurology
Annals of Neurology, 2020, 87 (6), pp.931--938. ⟨10.1002/ana.25730⟩
Scheldeman, L, Wouters, A, Boutitie, F, Dupont, P, Christensen, S, Cheng, B, Ebinger, M, Endres, M, Fiebach, J B, Gerloff, C, Muir, K W, Nighoghossian, N, Pedraza, S, Simonsen, C Z, Thijs, V, Thomalla, G, Lemmens, R & for the WAKE-UP Investigators 2020, ' Different Mismatch Concepts for Magnetic Resonance Imaging–Guided Thrombolysis in Unknown Onset Stroke ', Annals of Neurology, vol. 87, no. 6, pp. 931-938 . https://doi.org/10.1002/ana.25730
Annals of Neurology
Annals of Neurology, 2020, 87 (6), pp.931--938. ⟨10.1002/ana.25730⟩
Scheldeman, L, Wouters, A, Boutitie, F, Dupont, P, Christensen, S, Cheng, B, Ebinger, M, Endres, M, Fiebach, J B, Gerloff, C, Muir, K W, Nighoghossian, N, Pedraza, S, Simonsen, C Z, Thijs, V, Thomalla, G, Lemmens, R & for the WAKE-UP Investigators 2020, ' Different Mismatch Concepts for Magnetic Resonance Imaging–Guided Thrombolysis in Unknown Onset Stroke ', Annals of Neurology, vol. 87, no. 6, pp. 931-938 . https://doi.org/10.1002/ana.25730
OBJECTIVE: To explore the prevalence of the perfusion-weighted imaging (PWI)-diffusion-weighted imaging (DWI) mismatch and response to intravenous thrombolysis in the WAKE-UP trial. METHODS: We performed a prespecified post hoc analysis of ischemic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d4581416dbc2ffa3e11a3debdb2959