Výsledky vyhledávání - "methods [Gene Knock-In Techniques]"

Manipulating the Prion Protein Gene Sequence and Expression Levels with CRISPR/Cas9

Autor: Walker S. Jackson, Branko Zevnik, Lech Kaczmarczyk, Ylva Mende

Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0154604 (2016)
PLoS ONE
PLOS ONE 11(4), e0154604 (2016). doi:10.1371/journal.pone.0154604

The mammalian prion protein (PrP, encoded by Prnp) is most infamous for its central role in prion diseases, invariably fatal neurodegenerative diseases affecting humans, food animals, and animals in the wild. However, PrP is also hypothesized to be a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2bc7aa1dc42905e852a96ca5c1bc82
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-146267

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Visualizing corticotropin-releasing hormone receptor type 1 expression and neuronal connectivities in the mouse using a novel multifunctional allele

Autor: Claudia Kühne, Wolfgang Wurst, Jan M. Deussing, Jochen Graw, Martin Hrabě de Angelis, Günther Schütz, Oliver Puk

Publikováno v: The journal of comparative neurology 520(14), 3150-3180 (2012). doi:10.1002/cne.23082

The corticotropin-releasing hormone (CRH) and its type 1 receptor (CRHR1) play a central role in coordinating the endocrine, autonomic, and behavioral responses to stress. A prerequisite to functionally dissect the complexity of the CRH/CRHR1 system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e019eac943d77a8470d9746a0e157190
https://pubmed.ncbi.nlm.nih.gov/22886732

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