Zobrazeno 1 - 10
of 7 734
pro vyhledávání: '"metalloprotease"'
Autor:
Ke Shi, Sounak Bagchi, Jordis Bickel, Shiva H. Esfahani, Lulu Yin, Tiffany Cheng, Vardan T. Karamyan, Hideki Aihara
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract A zinc metallopeptidase neurolysin (Nln) processes diverse bioactive peptides to regulate signaling in the mammalian nervous system. To understand how Nln interacts with various peptides with dissimilar sequences, we determined crystal struc
Externí odkaz:
https://doaj.org/article/7de226a180964d149081f315fa64eeba
Autor:
Qibing Gu, Peijuan He, Qiankun Bai, Xiaojun Zhong, Yue Zhang, Jiale Ma, Huochun Yao, Zihao Pan
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-12 (2024)
Abstract Streptococcus suis (S. suis) is an important gram-positive pathogen and an emerging zoonotic pathogen that causes meningitis in swine and humans. Although several virulence factors have been characterized in S. suis, the underlying mechanism
Externí odkaz:
https://doaj.org/article/54305e487c6145c08d9528e69651c223
Autor:
Dongyang Zhou, Yan Wei, Shihao Sheng, Miaomiao Wang, Jiajing Lv, Bowen Zhao, Xiao Chen, Ke Xu, Long Bai, Yan Wu, Peiran Song, Liehu Cao, Fengjin Zhou, Hao Zhang, Zhongmin Shi, Jiacan Su
Publikováno v:
Bioactive Materials, Vol 37, Iss , Pp 378-392 (2024)
Posttraumatic osteoarthritis (PTOA) patients are often diagnosed by X-ray imaging at a middle-late stage when drug interventions are less effective. Early PTOA is characterized by overexpressed matrix metalloprotease 13 (MMP13). Herein, we constructe
Externí odkaz:
https://doaj.org/article/bf1d77c4081842d18c1ba3e0e28dcbeb
Autor:
Dalia González-Esparragoza, Alan Carrasco-Carballo, Nora H. Rosas-Murrieta, Lourdes Millán-Pérez Peña, Felix Luna, Irma Herrera-Camacho
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 4609-4629 (2024)
Ermp1 is a putative metalloprotease from Schizosaccharomyces pombe and a member of the Fxna peptidases. Although their function is unknown, orthologous proteins from rats and humans have been associated with the maturation of ovarian follicles and in
Externí odkaz:
https://doaj.org/article/e6df0069ed9747269a730ef743ed2e25
Publikováno v:
Open Biology, Vol 14, Iss 7 (2024)
Rheumatoid arthritis is a chronic inflammatory disease that shows characteristic diurnal variation in symptom severity, where joint resident fibroblast-like synoviocytes (FLS) act as important mediators of arthritis pathology. We investigate the role
Externí odkaz:
https://doaj.org/article/66b3aadbc6b24d708c7eb5a389aa1c52
Akademický článek
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Publikováno v:
Egyptian Pediatric Association Gazette, Vol 71, Iss 1, Pp 1-11 (2023)
Abstract Background Growing evidence implicates a pro-thrombotic state, caused by ADAMTS13 deficiency, in sepsis-associated organ dysfunction, but pediatric data is limited. Our purpose was to evaluate association of ADAMTS13 with prognosis of pediat
Externí odkaz:
https://doaj.org/article/adaa30f17a444e4c8ea9b8e1431d05e9
Autor:
Gerardo Ramírez-Rico, Lucero Ruiz-Mazón, Magda Reyes-López, Lina Rivillas Acevedo, Jesús Serrano-Luna, Mireya de la Garza
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8232 (2024)
Mannheimia haemolytica is the main etiological bacterial agent in ruminant respiratory disease. M. haemolytica secretes leukotoxin, lipopolysaccharides, and proteases, which may be targeted to treat infections. We recently reported the purification a
Externí odkaz:
https://doaj.org/article/b18ec2b72cfb4aa09b533c4a01e5b512
Autor:
Agata Wojtkowska, Anna Małek, Sławomir Giziński, Rafał Sapierzyński, Anna Rodo, Justyna Sokołowska, Katarzyna A. Zabielska-Koczywąs, Anna Wojtalewicz, Magdalena Walewska, Ewa Kautz, Magdalena Ostrzeszewicz, Roman Lechowski
Publikováno v:
Animals, Vol 14, Iss 14, p 2110 (2024)
Feline injection-site sarcomas (FISSs) are aggressive neoplasms that have been associated mostly with vaccination. Feline noninjection-site sarcomas (non-FISSs) are less frequently observed in cats and may arise in any anatomic site. This study aimed
Externí odkaz:
https://doaj.org/article/6adf4b4734574df98f429a4b1e106c5d
Autor:
Maryam Alipour, Leila Masoori, Mohammad Davoodzadeh Gholami, Majid Khoshmirsafa, Elham Razmjou, Nahid Jalallou, Farzane Jafarian, Reza Falak, Ahmad Reza Meamar
Publikováno v:
Iranian Journal of Parasitology, Vol 19, Iss 1 (2024)
Background: Uncovering the roles and characteristics of pathogenesis-related molecules can help us develop novel management methods in parasitology. In this study, we studied the expression levels of Strongyloides stercoralis heat shock protein70 (HS
Externí odkaz:
https://doaj.org/article/375eec955e864702af795236dfebf64e