Zobrazeno 1 - 10
of 86
pro vyhledávání: '"metal based compounds"'
Autor:
Veronica Ghini
Publikováno v:
Inorganics, Vol 12, Iss 6, p 168 (2024)
Despite the increasing interest in the development of novel metal-based compounds for cancer treatment, these molecules are currently poorly characterized in mechanistic terms, due to their multiple macromolecular targets inside the cells. In this re
Externí odkaz:
https://doaj.org/article/810a7fa794ce49d4be875fca37138850
Autor:
Tiago Costa, Maria I. Veiga, Nuno S. Osório, Nuno M. Neves, Helena Aguilar, Alexandra G. Fraga
Publikováno v:
Journal of Materials Research and Technology, Vol 24, Iss , Pp 6942-6957 (2023)
Microorganisms can be found in almost all environments with high-touch surfaces being an important fomite for microbial growth. Considering the health issues associated to acquired infection from inanimate surfaces, as well as the raising hygienic co
Externí odkaz:
https://doaj.org/article/c6864a16aacc4087bd45ce94e1a39643
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 8, Iss , Pp 100104- (2023)
In light of the current SARS-CoV-2 outbreak, about one million research papers (articles, reviews, communications, etc.) were published in the last one and a half years. It was also noticed that in the past few years; infectious diseases, mainly thos
Externí odkaz:
https://doaj.org/article/a9e78396cfc24b34ac1819812bf2eeb1
Akademický článek
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Autor:
Jana Hildebrandt, Norman Häfner, Helmar Görls, Marie-Christin Barth, Matthias Dürst, Ingo B. Runnebaum, Wolfgang Weigand
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6669 (2022)
(1) Background: Since the discovery of cisplatin’s cytotoxic properties, platinum(II) compounds have attracted much interest in the field of anticancer drug development. Over the last few years, classical structure–activity relationships (SAR) ha
Externí odkaz:
https://doaj.org/article/b48f08e1e17f4010bd753849dca9abee
Autor:
Jana Hildebrandt, Norman Häfner, Daniel Kritsch, Helmar Görls, Matthias Dürst, Ingo B. Runnebaum, Wolfgang Weigand
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4976 (2022)
(1) Background: Ruthenium and osmium complexes attract increasing interest as next generation anticancer drugs. Focusing on structure-activity-relationships of this class of compounds, we report on 17 different ruthenium(II) complexes and four promis
Externí odkaz:
https://doaj.org/article/e5dbb2f690384e328e6c6f048edf26ac
Autor:
Jinghong Chen, Xin Chen, Dacai Xu, Li Yang, Zhenjun Yang, Qianqian Yang, Ding Yan, Peiquan Zhang, Du Feng, Jinbao Liu
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Ubiquitin–proteasome system (UPS) and autophagy–lysosome pathway (ALP) are two major systems for protein quality control (PQC) in eukaryotic cells. Interconnectivity between these two pathways has been suggested, but the molecular detail of how t
Externí odkaz:
https://doaj.org/article/09e5948d1de44225972f2e4b66c21572
Autor:
Anna Clara M. Galdino, Lívia Viganor, Alexandre A. de Castro, Elaine F. F. da Cunha, Thaís P. Mello, Larissa M. Mattos, Marcos D. Pereira, Mary C. Hunt, Megan O’Shaughnessy, Orla Howe, Michael Devereux, Malachy McCann, Teodorico C. Ramalho, Marta H. Branquinha, André L. S. Santos
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Elastase B (lasB) is a multifunctional metalloenzyme secreted by the gram-negative pathogen Pseudomonas aeruginosa, and this enzyme orchestrates several physiopathological events during bacteria-host interplays. LasB is considered to be a potential t
Externí odkaz:
https://doaj.org/article/d5bd907c6bd14d5183fd0f1747dd8c52
Akademický článek
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Akademický článek
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