Zobrazeno 1 - 10
of 88
pro vyhledávání: '"metabotropic glutamate receptors (mGluRs)"'
Autor:
Leyi Huang, Wenjie Xiao, Yan Wang, Juan Li, Jiaoe Gong, Ewen Tu, Lili Long, Bo Xiao, Xiaoxin Yan, Lily Wan
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 2, Pp 360-368 (2024)
Epilepsy is a neurological disorder characterized by high morbidity, high recurrence, and drug resistance. Enhanced signaling through the excitatory neurotransmitter glutamate is intricately associated with epilepsy. Metabotropic glutamate receptors
Externí odkaz:
https://doaj.org/article/4461d288e33e4331a2a5b51c712ddb1f
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8249
We studied the neuroprotective properties of the non-competitive NMDA receptor antagonist memantine, in combination with a positive allosteric modulator of metabotropic glutamate receptors of Group III, VU 0422288. The treatment was started 48 h afte
Akademický článek
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Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Store-operated calcium entry (SOCE) is a Calcium (Ca2+) influx pathway activated by depletion of intracellular stores that occurs in eukaryotic cells. In neurons, the presence and functions of SOCE are still in question. Here, we show evidences for t
Externí odkaz:
https://doaj.org/article/68754b1fb97147c88ecfa91b8f846c1e
Akademický článek
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Autor:
Xu Zhang, Liansheng Qiao, Yankun Chen, Bowen Zhao, Yu Gu, Xiaoqian Huo, Yanling Zhang, Gongyu Li
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 1, p 163 (2018)
The metabotropic glutamate receptors (mGluRs) are known as both synaptic receptors and taste receptors. This feature is highly similar to the Property and Flavor theory of Traditional Chinese medicine (TCM), which has the pharmacological effect and f
Externí odkaz:
https://doaj.org/article/412307a6f38d47efb6d47ca358f8348e
Kniha
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Autor:
Feng Qian, Feng Ru Tang
Publikováno v:
Current Neuropharmacology
Neurotransmitter and receptor systems are involved in different neurological and neuropsychological disorders such as Parkinson#039;s disease, depression, Alzheimer's disease and epilepsy. Recent advances in studies of signal transduction pathways or
Autor:
Bo-Wen Zhao, Liansheng Qiao, Gongyu Li, Xiao-Qian Huo, Yanling Zhang, Yan-Kun Chen, Yu Gu, Xu Zhang
Publikováno v:
International Journal of Molecular Sciences; Volume 19; Issue 1; Pages: 163
International Journal of Molecular Sciences, Vol 19, Iss 1, p 163 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 1, p 163 (2018)
International Journal of Molecular Sciences
The metabotropic glutamate receptors (mGluRs) are known as both synaptic receptors and taste receptors. This feature is highly similar to the Property and Flavor theory of Traditional Chinese medicine (TCM), which has the pharmacological effect and f
Autor:
Connie Sanchez, Alan L. Pehrson
Publikováno v:
CNS Spectrums
Monoamine-based treatments for depression have evolved greatly over the past several years, but shortcomings such as suboptimal efficacy, treatment lag, and residual cognitive dysfunction are still significant. Preclinical and clinical studies using