Zobrazeno 1 - 10
of 39
pro vyhledávání: '"metabolism of lipids"'
Autor:
Markus Zweckstetter, King Faisal Yambire, Niels Denkert, Claudia Steinem, Nelli Teske, Daryna Tarasenko, Michael Meinecke, Ira Milosevic, Indrani Mukherjee, Garima Jaipuria, Benjamin Kroppen
Publikováno v:
Cellular and Molecular Life Sciences
Cellular and molecular life sciences 78(5), 2355-2370 (2021). doi:10.1007/s00018-020-03647-z
Cellular and molecular life sciences 78(5), 2355-2370 (2021). doi:10.1007/s00018-020-03647-z
Membrane remodeling is a critical process for many membrane trafficking events, including clathrin-mediated endocytosis. Several molecular mechanisms for protein-induced membrane curvature have been described in some detail. Contrary, the effect that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299604b0231580d1487db82e8f61580b
https://doi.org/10.1007/s00018-020-03647-z
https://doi.org/10.1007/s00018-020-03647-z
Autor:
Jean-Baptiste Manneville, Irene Brian, Silvia Pedretti, Patrizia Romani, Arianna Pocaterra, Mattia Forcato, Silvio Bicciato, Samuel Mathieu, Nico Mitro, Sirio Dupont, Matteo Audano, Giulia Santinon
Publikováno v:
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, In press, ⟨10.1038/s41556-018-0270-5⟩
Nature Cell Biology, Nature Publishing Group, In press, ⟨10.1038/s41556-018-0270-5⟩
International audience; Extracellular matrix (ECM) mechanical cues have powerful effects on cell proliferation, differentiation and death. Here, starting from an unbiased metabolomics approach, we identify synthesis of neutral lipids as a general res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac277feffe338407fa39d7570adb9c85
https://doi.org/10.1038/s41556-018-0270-5
https://doi.org/10.1038/s41556-018-0270-5
Autor:
Bradley T. Hyman, Susanne Wegmann, Daniel J. Müller, Katharina Tepper, Eckhard Mandelkow, Eva-Maria Mandelkow, Stefania A. Mari
Publikováno v:
Nano letters 18(5), 3271-3281 (2018). doi:10.1021/acs.nanolett.8b01085
Misfolding and aggregation of the neuronal, microtubule-associated protein tau is involved in the patho-genesis of Alzheimer’s disease and tauopathies. It has been proposed that neuronal membranes could play a role in tau release, internalization,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e17a9d72657c6ef680ce3ea72a011f
https://doi.org/10.1021/acs.nanolett.8b01085
https://doi.org/10.1021/acs.nanolett.8b01085
Autor:
Rico J. E. Derks, Frederick Campbell, Edgar Dawkins, Edith Winkler, Li Kong, Frits Kamp, Harald Steiner, Alexander Kros, Martin Giera
Publikováno v:
Biochimica et biophysica acta / Biomembranes 1862(5), 183200 (2020). doi:10.1016/j.bbamem.2020.183200
BBA-Biomembranes, 1862(5). ELSEVIER
BBA-Biomembranes, 1862(5). ELSEVIER
The biophysical properties and biological functions of membranes are highly dependent on lipid composition. Supplementing cellular membranes with very long chain fatty acids (vlcFAs) is notoriously difficult given the extreme insolubility of vlcFAs i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f208449ec0237cdb31de1110e65e9f5c
Autor:
Céline Galvagnion
Publikováno v:
Journal of Parkinson's Disease 7(3), 433-450 (2017). doi:10.3233/JPD-171103
α-synuclein is a small protein abundantly expressed in the brain and mainly located in synaptic terminals. The conversion of α-synuclein into oligomers and fibrils is the hallmark of a range of neurodegenerative disorders including Parkinson's dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0589abfe57381c718374882be6789174
https://pubmed.ncbi.nlm.nih.gov/28671142
https://pubmed.ncbi.nlm.nih.gov/28671142
Autor:
Šakienė, Rūta
Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly individuals in developed countries.The aetiology and pathogenesis of age-related macular degeneration is not absolutely clear. Knowing that the main pathological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2888::c77ee356956b0e852ff6772fe1848ecb
https://library.lsmuni.lt/LSMU:ELABAETD15928924&prefLang=en_US
https://library.lsmuni.lt/LSMU:ELABAETD15928924&prefLang=en_US
КОРРЕКЦИЯ ЛИПИДНОГО МЕТАБОЛИЗМА СВИНЕЙ БИОГЕННЫМИ СОЕДИНЕНИЯМИ В ЛОКАЛЬНЫХ БИОГЕОХИМИЧЕСКИХ УСЛОВИЯХ
The work purpose – to study corrective influence of the biogenous substance «Kombiolaks» in a complex with biological products of «DAFS-25» or «Selenopiran» on dynamics of an exchange of lipids at boars in agrosoil conditions of Prisurya of C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::659ab9964be4508dbb9f8e57e671799a
Autor:
Antti Nyyssölä, Mika Kaimainen, Heikki Kallio, Ulla Holopainen, Johanna Buchert, Ana M. Gil, Armando J. D. Silvestre, Pekka Lehtinen, Riikka Järvinen, Carlos Pascoal Neto
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Järvinen, R, Silvestre, A J D, Holopainen, U, Kaimainen, M, Nyyssölä, A, Gil, A M, Pascoal Neto, C, Lehtinen, P, Buchert, J & Kallio, H 2009, ' Suberin of potato ( Solanum tuberosum var. Nikola) : Comparison of the effect of cutinase CcCut1 with chemical depolymerization ', Journal of Agricultural and Food Chemistry, vol. 57, no. 19, pp. 9016-9027 . https://doi.org/10.1021/jf9008907
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Järvinen, R, Silvestre, A J D, Holopainen, U, Kaimainen, M, Nyyssölä, A, Gil, A M, Pascoal Neto, C, Lehtinen, P, Buchert, J & Kallio, H 2009, ' Suberin of potato ( Solanum tuberosum var. Nikola) : Comparison of the effect of cutinase CcCut1 with chemical depolymerization ', Journal of Agricultural and Food Chemistry, vol. 57, no. 19, pp. 9016-9027 . https://doi.org/10.1021/jf9008907
Chemical and enzymatic depolymerizations of suberin isolated from potato peel (Solanum tuberosum var. Nikola) were performed under various conditions. Enzymatic hydrolysis with cutinase CcCut1 and chemical methanolysis with NaOMe of suberin yielded m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbc408e460e923b574147de742aa5ca
https://doi.org/10.1021/jf9008907
https://doi.org/10.1021/jf9008907
Publikováno v:
Neuron 81(4), 717-719 (2014). doi:10.1016/j.neuron.2014.02.003
Retrograde signaling is a powerful tool to shape synaptic transmission, typically inducing inhibition of transmitter release. A new study published in this issue of Neuron by Carta et al. (2014) now provides strong support for arachidonic acid as a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fcb5e9e9ed8f7856a6b0c2dd00c3899
https://pub.dzne.de/record/137271
https://pub.dzne.de/record/137271
Publikováno v:
The journal of biological chemistry 287(25), 21326-21334 (2012). doi:10.1074/jbc.M112.356659
Pathogenic generation of amyloid β-peptide (Aβ) by sequential cleavage of β-amyloid precursor protein (APP) by β- and γ-secretases is widely believed to causally underlie Alzheimer disease (AD). β-Secretase initially cleaves APP thereby generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53372a6deee4dab521a68e6963aeebe0