Zobrazeno 1 - 10
of 11
pro vyhledávání: '"metabolism [Stroke]"'
Autor:
Christian J. Hoffmann, Diede W. M. Broekaart, Melanie T. C. Kuffner, Janet Lips, Antonino Asaro, Majed Kikhia, Philipp Boehm-Sturm, Monika Dopatka, Ulrich Dirnagl, Eleonora Aronica, Christoph Harms, Anna R. Malik, Susanne Mueller, Thomas E. Willnow, Malgorzata Gorniak‐Walas
Publikováno v:
Glia 68(6), 1304-1316 (2020). doi:10.1002/glia.23778
GLIA, 68(6), 1304-1316. John Wiley and Sons Inc.
Glia, 68(6), 1304-1316. John Wiley and Sons Inc.
GLIA, 68(6), 1304-1316. John Wiley and Sons Inc.
Glia, 68(6), 1304-1316. John Wiley and Sons Inc.
SorCS2 is an intracellular sorting receptor of the VPS10P domain receptor gene family recently implicated in oxidative stress response. Here, we interrogated the relevance of stress-related activities of SorCS2 in the brain by exploring its role in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c38756a939ab0f87dfa7138d287e22
https://doi.org/10.1002/glia.23778
https://doi.org/10.1002/glia.23778
Autor:
Clemens Messerschmidt, Marco Foddis, Sonja Blumenau, Susanne Müller, Kajetan Bentele, Manuel Holtgrewe, Celia Kun-Rodrigues, Isabel Alonso, Maria do Carmo Macario, Ana Sofia Morgadinho, Ana Graça Velon, Gustavo Santo, Isabel Santana, Saana Mönkäre, Liina Kuuluvainen, Johanna Schleutker, Minna Pöyhönen, Liisa Myllykangas, Assunta Senatore, Daniel Berchtold, Katarzyna Winek, Andreas Meisel, Aleksandra Pavlovic, Vladimir Kostic, Valerija Dobricic, Ebba Lohmann, Hasmet Hanagasi, Gamze Guven, Basar Bilgic, Jose Bras, Rita Guerreiro, Dieter Beule, Ulrich Dirnagl, Celeste Sassi
Publikováno v:
Scientific reports 11(1), 6072 (2021). doi:10.1038/s41598-021-84919-x
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Recently, several genome-wide association studies identified PHACTR1 as key locus for five diverse vascular disorders: coronary artery disease, migraine, fibromuscular dysplasia, cervical artery dissection and hypertension. Although these represent s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d760b308229fb529960863502c733cd1
https://refubium.fu-berlin.de/handle/fub188/38139
https://refubium.fu-berlin.de/handle/fub188/38139
Autor:
Lilian Staerck, Golo Kronenberg, Helmut Kettenmann, Friederike Klempin, Stephanie Wegner, Karen Gertz, Wolfgang Uckert, Nadine Richter, Matthias Endres, Ria Uhlemann, Susanne A. Wolf
Publikováno v:
Acta neuropathologica 135(4), 551-568 (2017). doi:10.1007/s00401-017-1795-6
After stroke, macrophages in the ischemic brain may be derived from either resident microglia or infiltrating monocytes. Using bone marrow (BM)-chimerism and dual-reporter transgenic fate mapping, we here set out to delimit the responses of either ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a437546f0aa140714a4c266aabf7cc
https://doi.org/10.1007/s00401-017-1795-6
https://doi.org/10.1007/s00401-017-1795-6
Publikováno v:
Glia 65(9), 1550-1561 (2017). doi:10.1002/glia.23183
Glia
Glia
Stroke is one of the leading causes of death and long-term disability. In the penumbra, that is, the area surrounding the infarct core, peri-infarct depolarizations (PIDs) are accompanied by strong intracellular calcium elevations in astrocytes and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588e1d215ae13eaf7c5463da0f71b6aa
https://doi.org/10.1002/glia.23183
https://doi.org/10.1002/glia.23183
Autor:
Jochner, Magdalena C. E., An, Junfeng, Lättig-Tünnemann, Gisela, Kirchner, Marieluise, Dagane, Alina, Dittmar, Gunnar, Dirnagl, Ulrich, Eickholt, Britta J., Harms, Christoph
Publikováno v:
Scientific reports 9(1), 3183 (2019). doi:10.1038/s41598-019-39438-1
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Phosphatase and tensin homolog (PTEN) signalling might influence neuronal survival after brain ischemia. However, the influence of the less studied longer variant termed PTEN-L (or PTENα) has not been studied to date. Therefore, we examined the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe3fd8a0d22d61bec4055744e1803c1
http://edoc.mdc-berlin.de/18081/1/18081oa.pdf
http://edoc.mdc-berlin.de/18081/1/18081oa.pdf
Autor:
Golo Kronenberg, Stephanie Wegner, Matthew Blake Wright, Matthias Endres, Ria Uhlemann, Valérie Boujon, Karen Gertz, Ulrich Laufs
Publikováno v:
Journal of molecular medicine 97(8), 1127-1138 (2019). doi:10.1007/s00109-019-01801-0
Journal of Molecular Medicine (Berlin, Germany)
Journal of Molecular Medicine (Berlin, Germany)
Peroxisome proliferator-activated receptors (PPARs) control the expression of genes involved in glucose homeostasis, lipid metabolism, inflammation, and cell differentiation. Here, we analyzed the effects of aleglitazar, a dual PPARα and PPARγ agon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f167de9aa317b1f36be7747dd6383118
https://pub.dzne.de/record/140815
https://pub.dzne.de/record/140815
Autor:
Nicolle Kränkel, Johann Bauersachs, Karin Weissenborn, Xinmin S. Li, Arash Haghikia, Udo Bavendiek, Aiden Haghikia, David Schmidt, Thomas G. Liman, Zeneng Wang, Weifei Zhu, Stanley L. Hazen, Kristina Sonnenschein, Nils Bledau, Friederike Zimmermann, Markus M. Heimesaat, Matthias Endres, Daniela Fraccarollo, Ulf Landmesser, Christian Widera
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology 38(9), 2225-2235 (2018). doi:10.1161/ATVBAHA.118.311023
Objective— Gut microbiota–dependent metabolites, in particular trimethylamine N -oxide (TMAO), have recently been reported to promote atherosclerosis and thrombosis. Here, we examined for the first time the relation of TMAO and the risk of incide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd3ed9add4b75e23c236b434248e17b
https://pubmed.ncbi.nlm.nih.gov/29976769
https://pubmed.ncbi.nlm.nih.gov/29976769
Autor:
Nadine Gladow, Mareike Thielke, Mihovil Mladinov, Philipp Mergenthaler, Josef Priller, Dana Bloomquist, Chotima Böttcher, Claudia Muselmann-Genschow, Dorette Freyer, Jojanneke H J Huck
Publikováno v:
Journal of Cerebral Blood Flow and Metabolism, 35, 1804-11
Journal of Cerebral Blood Flow and Metabolism, 35, 11, pp. 1804-11
Journal of cerebral blood flow & metabolism 35(11), 1804-1811 (2015). doi:10.1038/jcbfm.2015.128
Journal of Cerebral Blood Flow and Metabolism, 35, 11, pp. 1804-11
Journal of cerebral blood flow & metabolism 35(11), 1804-1811 (2015). doi:10.1038/jcbfm.2015.128
Item does not contain fulltext Dopamine is the predominant catecholamine in the brain and functions as a neurotransmitter. Dopamine is also a potent immune modulator. In this study, we have characterized the expression of dopamine receptors on murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d178ca71b8e597e0ea7ee0e5aa4b4c43
https://doi.org/10.1038/jcbfm.2015.128
https://doi.org/10.1038/jcbfm.2015.128
Publikováno v:
Cerebral cortex 28(12), 4264-4280 (2017). doi:10.1093/cercor/bhx280
In core regions of ischemic stroke, disruption of blood flow causes breakdown of ionic gradients and, ultimately, calcium overload and cell death. In the surrounding penumbra, cells may recover upon reperfusion, but recovery is hampered by additional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef13d446c64b26f564dcd92359d943f
https://pubmed.ncbi.nlm.nih.gov/29136153
https://pubmed.ncbi.nlm.nih.gov/29136153
Autor:
Peter J. Koudstaal, M. Arfan Ikram, Albert Hofman, Monique M.B. Breteler, Renske G. Wieberdink, Jacqueline C.M. Witteman
Publikováno v:
American journal of epidemiology 176(8), 699-707 (2012). doi:10.1093/aje/kws149
American Journal of Epidemiology, 176(8), 699-707. Oxford University Press
American Journal of Epidemiology, 176(8), 699-707. Oxford University Press
Insulin resistance, which plays a key role in the development of diabetes mellitus, is a putative modifiable risk factor for stroke. The aim of this study was to investigate if markers of insulin resistance were associated with risk of stroke in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b072e40f4d4de9607af5bb404001f9d
https://pure.eur.nl/en/publications/0245df0c-b4cf-4908-84d3-13b58b084f95
https://pure.eur.nl/en/publications/0245df0c-b4cf-4908-84d3-13b58b084f95