Zobrazeno 1 - 2
of 2
pro vyhledávání: '"metabolism [Squalene]"'
Autor:
Lena Spieth, Roman Sankowski, David Ewers, Martin Meschkat, Stefan A. Berghoff, Mikael Simons, Jan Winchenbach, Ting Sun, Julia M. Edgar, Gesine Saher, Torben Ruhwedel, Ludovico Cantuti-Castelvetri, Christine Stadelmann-Nessler, Franziska van der Meer, Francesca Odoardi, Wiebke Möbius, Tim Düking, Klaus-Armin Nave, Michael W. Sereda, Patricia Scholz, Constanze Depp, Lennart Schlaphoff, Marco Prinz, Jonathan Neuber, Andrew Octavian Sasmita, Inge Huitinga, Till Ischebeck, Leon Hosang
Publikováno v:
Nature Neuroscience, 24, 47-60. Nature Publishing Group
Nature neuroscience.
Nature neuroscience 24(1), 47-60 (2021). doi:10.1038/s41593-020-00757-6
Nature neuroscience
Nature neuroscience.
Nature neuroscience 24(1), 47-60 (2021). doi:10.1038/s41593-020-00757-6
Nature neuroscience
The repair of inflamed, demyelinated lesions as in multiple sclerosis (MS) necessitates the clearance of cholesterol-rich myelin debris by microglia/macrophages and the switch from a pro-inflammatory to an anti-inflammatory lesion environment. Subseq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3611e48234b6ab2743ff34a0d63b70e8
https://pure.knaw.nl/portal/en/publications/99839925-2317-482f-84d3-35ccaca51264
https://pure.knaw.nl/portal/en/publications/99839925-2317-482f-84d3-35ccaca51264
Autor:
Alberto Ballestrero, Lorenzo Ferrando, Edoardo Isnaldi, Gabriella Cirmena, Marilena De Mariano, Paola Franceschelli, Gabriele Zoppoli
Publikováno v:
Cancer letters. 425
Oncogenic alteration of the cholesterol synthesis pathway is a recognized mechanism of metabolic adaptation. In the present review, we focus on squalene epoxidase (SE), one of the two rate-limiting enzymes in cholesterol synthesis, retracing its hist