Zobrazeno 1 - 5
of 5
pro vyhledávání: '"metabolism [Receptors, Metabotropic Glutamate]"'
Autor:
Georg Köhr, Dušica Briševac, Dan Du, Ralf Scholz, Mohammad Nael Elagabani, Hans-Christian Kornau
Publikováno v:
Journal of neurochemistry 157(3), 666-683 (2021). doi:10.1111/jnc.15230
Journal of Neurochemistry : official journal of the International Society for Neurochemistry
Journal of Neurochemistry : official journal of the International Society for Neurochemistry
Fragile X syndrome (FXS), the most common inherited cause of intellectual disability, results from silencing of the fragile X mental retardation gene 1 (FMR1). The analyses of FXS patients’ brain autopsies revealed an increased density of immature
Autor:
Moritz J. Frech, Michael Rabenstein, Zhen Wang, Andreas Wree, Jiankai Luo, Xiao Feng, Anne Gläser, Martin Witt, Andreas Hermann, Fan Yang, Anja U Bräuer, Arndt Rolfs
Publikováno v:
Cerebral cortex 30(3), 1465-1480 (2019). doi:10.1093/cercor/bhz179
Niemann–Pick type C1 (NPC1) disease is characterized by neurodegeneration caused by cholesterol accumulation in the late endosome/lysosome. In this study, a defective basal and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-stimulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c382fe91f25359270c840278297de72
Autor:
Ulrike Pannasch, Hai Ying Zhang, A. Wojtalla, David M. Otte, Andreas Zimmer, A. Vanessa Stempel, Anne Kathrin Theis, Ildiko Racz, Dietmar Schmitz, Zheng-Xiong Xi, Alexander Stumpf, Tugba Özdogan, Alexey Ponomarenko
Publikováno v:
Neuron 90(4), 795-809 (2016). doi:10.1016/j.neuron.2016.03.034
Neuron, 90(4): 670-671
Neuron
Neuron, 90(4): 670-671
Neuron
Endocannabinoids (eCBs) exert major control over neuronal activity by activating cannabinoid receptors (CBRs). The functionality of the eCB system is primarily ascribed to the well-documented retrograde activation of presynaptic CB1Rs. We find that a
Autor:
Eva Ferreira Rodrigues, Jochen Herms, Saak V. Ovsepian, Susana Valero Freitag, Lidia Blazquez-Llorca
Publikováno v:
Cerebral cortex 27(10), cercor;bhw267v1 (2016). doi:10.1093/cercor/bhw267
Synaptic dysfunctions and altered neuronal activity play major role in the pathophysiology of Alzheimer's disease (AD), with underlying mechanisms largely unknown. We report that in the prefrontal cortex of amyloid precursor protein-presenilin 1 and
Autor:
Angela Seebahn, Nico Vogel, Jeannine Mohrlüder, Rudolf Hartmann, Heinrich Sticht, Ralf Enz, Holger Dinkel, Cord-Michael Becker
Publikováno v:
FEBS letters 585, 511-516 (2011). doi:10.1016/j.febslet.2010.12.042
Metabotropic glutamate receptors (mGluRs) are regulated by interacting proteins that mostly bind to their intracellular C-termini. Here, we investigated if mGluR6, mGluR7a and mGluR8a C-termini form predefined binding surfaces or if they were rather