Zobrazeno 1 - 4
of 4
pro vyhledávání: '"metabolism [RNA, Untranslated]"'
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 2 (2021)
Disease models & mechanisms 14(2), dmm047803 (2021). doi:10.1242/dmm.047803
Dis. Model. Mech. 14:dmm047803 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease models & mechanisms 14(2), dmm047803 (2021). doi:10.1242/dmm.047803
Dis. Model. Mech. 14:dmm047803 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record
Gene trapping is a high-throughput approach that has been used to introduce insertional mutations into the genome of mouse embryonic stem (ES) cells. It is performed with generic gene trap vectors that simultaneously mutate and report the expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126c1985eeec2ee888a6b678f6813bf7
http://dmm.biologists.org/content/14/2/dmm047803
http://dmm.biologists.org/content/14/2/dmm047803
Autor:
Andre Fischer, Dennis M. Krüger, Sarah Köster, Tea Berulava, Gerrit Brehm, Rezaul Islam, Robert Epple
Publikováno v:
Mol Neurobiol
Molecular neurobiology 58(6), 2940-2953 (2021). doi:10.1007/s12035-021-02296-y
Molecular Neurobiology
Molecular neurobiology 58(6), 2940-2953 (2021). doi:10.1007/s12035-021-02296-y
Molecular Neurobiology
Neurons are highly compartmentalized cells that depend on local protein synthesis. Messenger RNAs (mRNAs) have thus been detected in neuronal dendrites, and more recently in the pre- and postsynaptic compartments as well. Other RNA species such as mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71ab3d3b00a748e0e3acbc531878a2a
https://pubmed.ncbi.nlm.nih.gov/33710584
https://pubmed.ncbi.nlm.nih.gov/33710584
Publikováno v:
Methods 121-122, 55-67 (2017)
Methods 121-122, 55-67 (2017). doi:10.1016/j.ymeth.2017.02.008
Methods 121-122, 55-67 (2017). doi:10.1016/j.ymeth.2017.02.008
The generation of targeted mouse mutants is a key technology for biomedical research. Using the CRISPR/Cas9 system for induction of targeted double-strand breaks, gene editing can be performed in a single step directly in mouse zygotes. This article
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2d957046138368c25b3c5ac9dc8f26
https://pubmed.ncbi.nlm.nih.gov/28263886
https://pubmed.ncbi.nlm.nih.gov/28263886
Autor:
Stefanie Könen, Daniela Cadinu, Dorthe Matenia, Astrid Sydow, Frank J.A. Dennissen, Maria Joseph, Eva-Maria Mandelkow, Olga Petrova, Katja Hochgräfe
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications 4(1), 17 (2016). doi:10.1186/s40478-016-0281-z
Acta Neuropathologica Communications 4(1), 17 (2016). doi:10.1186/s40478-016-0281-z
Introduction Mutations of Tau are associated with several neurodegenerative disorders. Recently, the Tau mutation A152T was described as a novel risk factor for frontotemporal dementia spectrum disorders and Alzheimer disease. In vitro Tau-A152T show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ceb231bda414c234a95def42e03d87