Zobrazeno 1 - 10
of 27
pro vyhledávání: '"metabolism [Prion Diseases]"'
Autor:
Valerie L. Sim, José Eriton Gomes da Cunha, Niels Kruse, Óscar López-Pérez, Katrin Thüne, Enric Vidal, Peter Hermann, Inga Zerr, Miguel Calero, Henrik Zetterberg, Daniela Diaz-Lucena, Matthias Schmitz, Anna Villar-Piqué, Franc Llorens, Hailey Pineau, Alba Marín-Moreno, Raquel Sánchez-Valle, Joachim Riggert, José Antonio del Río, Kaj Blennow, Pol Andrés-Benito, Juan María Torres, Isidre Ferrer, Brit Mollenhauer, Anna Ladogana, Juan Carlos Espinosa
Publikováno v:
IRTA Pubpro. Open Digital Archive
Institut de Recerca i Tecnologia Agroalimentàries (IRTA)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
Acta neuropathologica 141(6), 841-859 (2021). doi:10.1007/s00401-021-02296-1
Repisalud
Instituto de Salud Carlos III (ISCIII)
Acta Neuropathologica
Institut de Recerca i Tecnologia Agroalimentàries (IRTA)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
Acta neuropathologica 141(6), 841-859 (2021). doi:10.1007/s00401-021-02296-1
Repisalud
Instituto de Salud Carlos III (ISCIII)
Acta Neuropathologica
19 Pág. Centro de Investigación en Sanidad Animal (CISA)
Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune cell surface receptor that regulates microglial function and is involved in the pathophysiology of several ne
Triggering receptor expressed on myeloid cells 2 (TREM2) is an innate immune cell surface receptor that regulates microglial function and is involved in the pathophysiology of several ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4c2d5d390d0014fe2441e27c752af2
https://doi.org/10.1007/s00401-021-02296-1
https://doi.org/10.1007/s00401-021-02296-1
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-10 (2021)
Acta Neuropathologica Communications 9(1), 187 (2021). doi:10.1186/s40478-021-01286-4
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-10 (2021)
Acta Neuropathologica Communications 9(1), 187 (2021). doi:10.1186/s40478-021-01286-4
In sporadic Creutzfeldt–Jakob disease (sCJD), the pathological changes appear to be restricted to the central nervous system. Only involvement of the trigeminal ganglion is widely accepted. The present study systematically examined the involvement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557de0227f1c37e42144ba6d5dd01747
Autor:
Stefanie-Elisabeth Heumüller, Annika C. Hornberger, Alina S. Hebestreit, André Hossinger, Ina M. Vorberg
Publikováno v:
International journal of molecular sciences 23(6), 2909 (2022). doi:10.3390/ijms23062909
Transmissible spongiform encephalopathies or prion disorders are fatal infectious diseases that cause characteristic spongiform degeneration in the central nervous system. The causative agent, the so-called prion, is an unconventional infectious agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5853603e27113507f57dc8ec2ed25981
https://pubmed.ncbi.nlm.nih.gov/35328330
https://pubmed.ncbi.nlm.nih.gov/35328330
Autor:
Marco Zattoni, Marika Mearelli, Silvia Vanni, Arianna Colini Baldeschi, Thanh Hoa Tran, Chiara Ferracin, Marcella Catania, Fabio Moda, Giuseppe Di Fede, Giorgio Giaccone, Fabrizio Tagliavini, Gianluigi Zanusso, James W. Ironside, Isidre Ferrer, Giuseppe Legname
Publikováno v:
Molecular neurobiology 59, 3778-3799 (2022). doi:10.1007/s12035-022-02817-3
Zattoni, M, Mearelli, M, Vanni, S, Colini Baldeschi, A, Tran, T H, Ferracin, C, Catania, M, Moda, F, Di Fede, G, Giaccone, G, Tagliavini, F, Zanusso, G, Ironside, J W, Ferrer, I & Legname, G 2022, ' Serpin Signatures in Prion and Alzheimer’s Diseases ', Molecular Neurobiology . https://doi.org/10.1007/s12035-022-02817-3
Zattoni, M, Mearelli, M, Vanni, S, Colini Baldeschi, A, Tran, T H, Ferracin, C, Catania, M, Moda, F, Di Fede, G, Giaccone, G, Tagliavini, F, Zanusso, G, Ironside, J W, Ferrer, I & Legname, G 2022, ' Serpin Signatures in Prion and Alzheimer’s Diseases ', Molecular Neurobiology . https://doi.org/10.1007/s12035-022-02817-3
Serpins represent the most broadly distributed superfamily of proteases inhibitors. They contribute to a variety of physiological functions and any alteration of the serpin-protease equilibrium can lead to severe consequences. SERPINA3 dysregulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50672703a3fd1c548ba21b1aaf0f471
Publikováno v:
Prion 11(2), 98-112 (2017). doi:10.1080/19336896.2017.1306162
Prion
Prion
Extracellular vesicles (EVs) are actively secreted, membrane-bound communication vehicles that exchange biomolecules between cells. EVs also serve as dissemination vehicles for pathogens, including prions, proteinaceous infectious agents that cause t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6afa19493cd9d1a2e191c748db81c4c
https://doi.org/10.1080/19336896.2017.1306162
https://doi.org/10.1080/19336896.2017.1306162
Autor:
Orr Shormoni, Inga Zerr, Katrin Thüne, Eirini Kanata, Juan Carlos Espinosa, Franc Llorens, Matthias Schmitz, Olivier Andreoletti, Athanasios Dimitriadis, Vincenzo Capece, Nikolaos Bekas, Stefan Bonn, Dimitra Dafou, Alba Marín-Moreno, Juan María Torres, Isidre Ferrer, Konstantinos Xanthopoulos, Theodoros Sklaviadis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (39), pp.19727-19735. ⟨10.1073/pnas.1803521116⟩
Proceedings of the National Academy of Sciences of the United States of America 116(39), 19727-19735 (2019). doi:10.1073/pnas.1803521116
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (39), pp.19727-19735. ⟨10.1073/pnas.1803521116⟩
Proceedings of the National Academy of Sciences of the United States of America 116(39), 19727-19735 (2019). doi:10.1073/pnas.1803521116
Significance Prion diseases are fatal neurodegenerative disorders characterized by rapidly progressive dementia. Sporadic Creutzfeldt–Jakob disease (sCJD) is the most prevalent. We report that, specific gene-expression alterations utilizing a relia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6cc12a96c15fff08728356383f782ab
https://hal.inrae.fr/hal-03199348/file/pnas-09-2019.pdf
https://hal.inrae.fr/hal-03199348/file/pnas-09-2019.pdf
Autor:
Mathias Jucker, Hermann C. Altmeppen, Juliane Schelle, Petra Schwarz, Markus Glatzel, Jay Rasmussen, Susanne Krasemann, Adriano Aguzzi
Publikováno v:
Acta neuropathologica 135(6), 965-967 (2018). doi:10.1007/s00401-018-1848-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55306a546ad630953caa7feef48e9862
https://pub.dzne.de/record/139952
https://pub.dzne.de/record/139952
Autor:
Walker S. Jackson, Surachai Supattapone, Daniel J. Walsh, Michael B. Miller, Geoffrey P. Noble
Publikováno v:
Biochemistry 54(5), 1180-1187 (2015). doi:10.1021s/bi501495j
Misfolding of the prion protein (PrP) plays a central role in the pathogenesis of infectious, sporadic, and inherited prion diseases. Here we use a chemically defined prion propagation system to study misfolding of the pathogenic PrP mutant D177N in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b475bb2cc0268f707a83f930223625a0
https://doi.org/10.1021/bi501495j
https://doi.org/10.1021/bi501495j
Autor:
Jesús R. Requena, Juan María Torres, Franc Llorens, Inga Zerr, Isidro Ferrer, Agata Mata, Katrin Thüne, Alejandro M. Sevillano, Silvia Vilches, Rosalina Gavín, Olivier Andreoletti, Juan Carlos Espinosa, Laura Urrea, José Antonio del Río
Publikováno v:
Repositorio de Resultados de Investigación del INIA
INIA: Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2017, 54 (8), pp.6412-6425. ⟨10.1007/s12035-016-0177-8⟩
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Molecular neurobiology 54(8), 6412-6425 (2016). doi:10.1007/s12035-016-0177-8
INIA: Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2017, 54 (8), pp.6412-6425. ⟨10.1007/s12035-016-0177-8⟩
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Molecular neurobiology 54(8), 6412-6425 (2016). doi:10.1007/s12035-016-0177-8
Reelin is an extracellular glycoprotein involved in key cellular processes in developing and adult nervous system, including regulation of neuronal migration, synapse formation, and plasticity. Most of these roles are mediated by the intracellular ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9b7f6eb472672bf32b4d8f6fe47b0c
https://hdl.handle.net/20.500.12792/2828
https://hdl.handle.net/20.500.12792/2828
Autor:
Susana Margarida da Silva Correia, Saima Zafar, Maria Cramm, Matthias Schmitz, Amandeep Singh Arora, Franc Llorens, Niccolò Candelise, Anna Villar-Piqué, Inga Zerr
Publikováno v:
Expert review of molecular diagnostics 17(10), 897-904 (2017). doi:10.1080/14737159.2017.1368389
Introduction: The development of in vitro protein misfolding amplification assays for the detection and analysis of abnormally folded proteins, such as proteinase K resistant prion protein (PrPres) was a major innovation in the prion field. In prion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d2af5a75c8db2ed07c94752fc9c337