Zobrazeno 1 - 10
of 16
pro vyhledávání: '"metabolism [Presynaptic Terminals]"'
Autor:
Garner, Craig, Ackermann, Frauke
Publikováno v:
Molecular and cellular neuroscience 124, 103795 (2023). doi:10.1016/j.mcn.2022.103795
Properly working synapses are one important guarantor for a functional and healthy brain. They are small, densely packed structures, where information is transmitted through the release of neurotransmitters from synaptic vesicles (SVs). The latter cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68d445588caeaaa0e207bb1bb44cbbe
Publikováno v:
Cells; Volume 11; Issue 19; Pages: 3150
Cells 11(19), 3150 (2022). doi:10.3390/cells11193150 special issue: "10th Anniversary of Cells—Advances in Cell Microenvironment"
Cells 11(19), 3150 (2022). doi:10.3390/cells11193150 special issue: "10th Anniversary of Cells—Advances in Cell Microenvironment"
The concept of the tripartite synapse describes the close interaction of pre- and postsynaptic elements and the surrounding astrocyte processes. For glutamatergic synapses, it is established that the presence of astrocytic processes and their structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3efa1e54a52f718f4dcf1f2e598b15a0
Autor:
Marta Orlando, Felicitas Bruentgens, Jörg Breustedt, Benjamin R. Rost, Stephan J. Sigrist, Dietmar Schmitz, Marta Maglione, Anton Dvorzhak
Publikováno v:
PLoS Biology, Vol 19, Iss 6, p e3001149 (2021)
PLoS Biology
PLoS biology 19(6), e3001149 (2021). doi:10.1371/journal.pbio.3001149
PLoS Biology
PLoS biology 19(6), e3001149 (2021). doi:10.1371/journal.pbio.3001149
Synaptic plasticity is a cellular model for learning and memory. However, the expression mechanisms underlying presynaptic forms of plasticity are not well understood. Here, we investigate functional and structural correlates of presynaptic potentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686a88e8516a9b4184c47ce383ba0f9d
https://doaj.org/article/35a0de84c74149958f7cff9c2f5f141c
https://doaj.org/article/35a0de84c74149958f7cff9c2f5f141c
Publikováno v:
Cellular and Molecular Life Sciences
Cellular and molecular life sciences, 78(6):2621-2639
Cellular and molecular life sciences 78(6), 2621-2639 (2021). doi:10.1007/s00018-020-03722-5
Cellular and molecular life sciences, 78(6):2621-2639
Cellular and molecular life sciences 78(6), 2621-2639 (2021). doi:10.1007/s00018-020-03722-5
The complex morphology of neurons, the specific requirements of synaptic neurotransmission and the accompanying metabolic demands create a unique challenge for proteostasis. The main machineries for neuronal protein synthesis and degradation are loca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69e34c3dccfa12d7b55f983609a377db
https://pubmed.ncbi.nlm.nih.gov/33340068
https://pubmed.ncbi.nlm.nih.gov/33340068
Autor:
Sheila Hoffmann-Conaway, Anil Annamneedi, Craig C. Garner, Eckart D. Gundelfinger, Carolina Montenegro-Venegas
Publikováno v:
Autophagy
Autophagy 16(9), 1732-1733 (2020). doi:10.1080/15548627.2020.1801259
Autophagy 16(9), 1732-1733 (2020). doi:10.1080/15548627.2020.1801259
Maintaining the integrity and function of the presynaptic neurotransmitter release apparatus is a demanding process for a post-mitotic neuron; the mechanisms behind it are still unclear. BSN (bassoon), an active zone scaffolding protein, has been imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b239874d386474f53b47c9a30e994a0
https://doi.org/10.1080/15548627.2020.1801259
https://doi.org/10.1080/15548627.2020.1801259
Autor:
Christine E Gee, Jessica Mitlöhner, Alexander Dityatev, Hartmut Niekisch, Renato Frischknecht, Max F. K. Happel, Constanze I. Seidenbecher, Rahul Kaushik, Eckart D. Gundelfinger, Armand Blondiaux
Publikováno v:
Cells
Cells 9(2), 260 (2020). doi:10.3390/cells9020260
Cells, 9(2):260
Cells, Vol 9, Iss 2, p 260 (2020)
Volume 9
Issue 2
Cells 9(2), 260 (2020). doi:10.3390/cells9020260
Cells, 9(2):260
Cells, Vol 9, Iss 2, p 260 (2020)
Volume 9
Issue 2
In the brain, Hebbian-type and homeostatic forms of plasticity are affected by neuromodulators like dopamine (DA). Modifications of the perisynaptic extracellular matrix (ECM), which control the functions and mobility of synaptic receptors as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705f575a9b5cc35954059eb0cd2dc7f4
https://pubmed.ncbi.nlm.nih.gov/31972963
https://pubmed.ncbi.nlm.nih.gov/31972963
Autor:
Hartmut T. Bocker, Julia Preobraschenski, Theresa Heinrich, Lutz Liebmann, Eric Seemann, Reinhard Jahn, Michael M. Kessels, J. Christopher Hennings, Melanie Gerth, Igor Jakovcevski, Christian A. Hübner, Britta Qualmann, Martin Westermann, Dirk Isbrandt
Publikováno v:
Cerebral Cortex
Cerebral cortex 29(10), 4263-4276 (2018). doi:10.1093/cercor/bhy308
Cerebral cortex 29(10), 4263-4276 (2018). doi:10.1093/cercor/bhy308
Brain functions are extremely sensitive to pH changes because of the pH-dependence of proteins involved in neuronal excitability and synaptic transmission. Here, we show that the Na+/H+ exchanger Nhe1, which uses the Na+ gradient to extrude H+, is ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea2b642d6617934cef548fda5e16493
https://hdl.handle.net/21.11116/0000-0004-AC16-221.11116/0000-0004-AC17-121.11116/0000-0002-AF9A-C
https://hdl.handle.net/21.11116/0000-0004-AC16-221.11116/0000-0004-AC17-121.11116/0000-0002-AF9A-C
Autor:
R. Jeroen Pasterkamp, Manuela Neumann, Mustapha Oulad-Abdelghani, Chieh-Yu Cheng, Julie Tahraoui-Bories, Chantal Sellier, Regina Feederle, Petra Frick, Dieter Edbauer, Nicolas Charlet-Berguerand, Cécile Martinat, Ian R. A. Mackenzie, Johannes Prudlo
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, BioMed Central part of Springer Science, 2018, 6 (1), ⟨10.1186/s40478-018-0579-0⟩
Acta Neuropathologica Communications, 2018, 6 (1), ⟨10.1186/s40478-018-0579-0⟩
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-17 (2018)
Acta Neuropathol. Commun. 6:72 (2018)
Acta Neuropathologica Communications 6(1), 72 (2018). doi:10.1186/s40478-018-0579-0
Acta Neuropathologica Communications, BioMed Central part of Springer Science, 2018, 6 (1), ⟨10.1186/s40478-018-0579-0⟩
Acta Neuropathologica Communications, 2018, 6 (1), ⟨10.1186/s40478-018-0579-0⟩
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-17 (2018)
Acta Neuropathol. Commun. 6:72 (2018)
Acta Neuropathologica Communications 6(1), 72 (2018). doi:10.1186/s40478-018-0579-0
Hexanucleotide repeat expansion in C9orf72 is the most common genetic cause of frontotemporal dementia and amyotrophic lateral sclerosis, but the pathogenic mechanism of this mutation remains unresolved. Haploinsufficiency has been proposed as one po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14cc66032c715f6812ce4cede48be218
https://hal.archives-ouvertes.fr/hal-03339513
https://hal.archives-ouvertes.fr/hal-03339513
Autor:
Eckart D. Gundelfinger, Wolfgang Tischmeyer, Sabrina Müller, Frank Angenstein, Eike Budinger, Anna Fejtova, Dirk Montag, Gürsel Çalışkan, Anil Annamneedi, Oliver Stork
Publikováno v:
Brain structure & function 223(7), 3423-3445 (2018). doi:10.1007/s00429-018-1692-3
Brain Structure & Function
Brain structure & function, 223(7):3423-3445
Brain Structure & Function
Brain structure & function, 223(7):3423-3445
Bassoon is a large scaffolding protein of the presynaptic active zone involved in the development of presynaptic terminals and in the regulation of neurotransmitter release at both excitatory and inhibitory brain synapses. Mice with constitutive abla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1783b1152bc05f81496da78ea2aee22c
Autor:
Vinita Bharat, Michael Siebrecht, Katja Burk, Saheeb Ahmed, Carsten Reissner, Mahdokht Kohansal-Nodehi, Vicky Steubler, Markus Zweckstetter, Jonathan T. Ting, Camin Dean
Publikováno v:
Cell Reports
Cell reports 21(8), 2118-2133 (2017). doi:10.1016/j.celrep.2017.10.084
Cell Reports, Vol 21, Iss 8, Pp 2118-2133 (2017)
Cell reports 21(8), 2118-2133 (2017). doi:10.1016/j.celrep.2017.10.084
Cell Reports, Vol 21, Iss 8, Pp 2118-2133 (2017)
Summary Delivery of neurotrophins and neuropeptides via long-range trafficking of dense core vesicles (DCVs) from the cell soma to nerve terminals is essential for synapse modulation and circuit function. But the mechanism by which transiting DCVs ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::bc8aeca36b5c3d33f817800fa240b809
https://hdl.handle.net/11858/00-001M-0000-002E-55C5-F11858/00-001M-0000-002E-55C3-4
https://hdl.handle.net/11858/00-001M-0000-002E-55C5-F11858/00-001M-0000-002E-55C3-4