Zobrazeno 1 - 10
of 16
pro vyhledávání: '"metabolism [Nerve Net]"'
Autor:
Chiesa, Patrizia A, Cavedo, Enrica, Initiative, INSIGHT-preAD Study Group and the Alzheimer Precision Medicine, Grothe, Michel J, Houot, Marion, Teipel, Stefan J, Potier, Marie-Claude, Habert, Marie-Odile, Lista, Simone, Dubois, Bruno, Hampel, Harald
Publikováno v:
Radiology 290(1), 167-176 (2019). doi:10.1148/radiol.2018180268
Purpose To evaluate the association between the global fibrillary amyloid-β pathology and the basal forebrain connectivity at rest in cognitively intact older adults at risk for Alzheimer disease. Materials and Methods This retrospective study was a
Autor:
Ewa Baczynska, David Baidoe-Ansah, Jakub Wlodarczyk, Luisa Strackeljan, Alexander Dityatev, Rahul Kaushik, Carla Cangalaya
Publikováno v:
Cells
Cells 10(8), 1862 (2021). doi:10.3390/cells10081862
Cells, Vol 10, Iss 1862, p 1862 (2021)
Volume 10
Issue 8
Cells 10(8), 1862 (2021). doi:10.3390/cells10081862
Cells, Vol 10, Iss 1862, p 1862 (2021)
Volume 10
Issue 8
The extracellular matrix (ECM) plays a key role in synaptogenesis and the regulation of synaptic functions in the central nervous system. Recent studies revealed that in addition to dopaminergic and serotoninergic neuromodulatory systems, microglia a
Autor:
Ivan Lazarevich, Maiya A. Rozhnova, Sergey V. Stasenko, Alexander Dityatev, Victor B. Kazantsev, Evgeniya V. Pankratova
Publikováno v:
PLoS ONE
PLOS ONE 15(1), e0227917 (2020). doi:10.1371/journal.pone.0227917
PLoS ONE, Vol 15, Iss 1, p e0227917 (2020)
PLOS ONE 15(1), e0227917 (2020). doi:10.1371/journal.pone.0227917
PLoS ONE, Vol 15, Iss 1, p e0227917 (2020)
Experimental studies highlight the important role of the extracellular matrix (ECM) in the regulation of neuronal excitability and synaptic connectivity in the nervous system. In its turn, the neural ECM is formed in an activity-dependent manner. Its
Autor:
Alexander Drzezga
Publikováno v:
Journal of nuclear medicine 59(11), 1645-1648 (2018). doi:10.2967/jnumed.117.206300
The network degeneration hypothesis suggests that neurodegenerative disorders are characterized by the spread of molecular neuropathologic features along specific neuronal brain networks, leading to functional impairment of these networks. Interestin
Publikováno v:
Journal of the Royal Society Interface
Interface 16(159), 20190356 (2019). doi:10.1098/rsif.2019.0356
Interface 16(159), 20190356 (2019). doi:10.1098/rsif.2019.0356
The prion hypothesis states that misfolded proteins can act as infectious agents that template the misfolding and aggregation of healthy proteins to transmit a disease. Increasing evidence suggests that pathological proteins in neurodegenerative dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fe85f97a3c604a2f2f7ea3e2eb377e
https://ora.ox.ac.uk/objects/uuid:a7533fff-71b4-4fc8-a086-db71b68fb9b0
https://ora.ox.ac.uk/objects/uuid:a7533fff-71b4-4fc8-a086-db71b68fb9b0
Autor:
Christian Baeuchl, Hsiang-Yu Chen, Yu-Shiang Su, Dorothea Hämmerer, Manousos A Klados, Shu-Chen Li
Publikováno v:
PLoS ONE
PLOS ONE 14(5), e0215849 (2019). doi:10.1371/journal.pone.0215849
PLoS ONE, Vol 14, Iss 5, p e0215849 (2019)
PLOS ONE 14(5), e0215849 (2019). doi:10.1371/journal.pone.0215849
PLoS ONE, Vol 14, Iss 5, p e0215849 (2019)
Aging and dopamine modulation have both been independently shown to influence the functional connectivity of brain networks during rest. Dopamine modulation is known to decline during the course of aging. Previous evidence also shows that the dopamin
Autor:
Marcy Zenobi-Wong, Srinivas Madduri, Frank Bradke, Andreas Husch, Nicolas Broguiere, Gemma Palazzolo
Publikováno v:
Biomaterials, 200
Biomaterials 200, 56-65 (2019). doi:10.1016/j.biomaterials.2019.01.047
Biomaterials 200, 56-65 (2019). doi:10.1016/j.biomaterials.2019.01.047
A method to generate injectable macroporous hydrogels based on partitioning of polyethylene glycol (PEG) and high viscous polysaccharides is presented. Step growth polymerization of PEG was used to initiate a phase separation and the formation of a c
Autor:
Bradley T. Hyman, Naomi Klickstein, Marc Aurel Busche, George A. Carlson, Tarun V. Kamath, Julia Schiantarelli, Israel Nelken, Susanne Wegmann, Simon Dujardin, Caitlin Commins
Publikováno v:
Nature reviews / Neuroscience 22(1), 57-64 (2018). doi:10.1038/s41593-018-0289-8
The coexistence of amyloid-β (Aβ) plaques and tau neurofibrillary tangles in the neocortex is linked to neural system failure and cognitive decline in Alzheimer’s disease. However, the underlying neuronal mechanisms are unknown. By employing in v
Autor:
Meng Li, Catie Chang, Oliver Speck, Hans-Jochen Heinze, Adam Safron, Bharat B. Biswal, Giacomo Salvadore, L Colic, Anna Fejtova, Helen S. Mayberg, Marie Woelfer, Martin Walter
Publikováno v:
European archives of psychiatry and clinical neuroscience 270(2), 207-216 (2018). doi:10.1007/s00406-018-0942-y
Ketamine exerts rapid antidepressant effects peaking 24 h after a single infusion, which have been suggested to be reflected by both reduced functional connectivity (FC) within default mode network (DMN) and altered glutamatergic levels in the perige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0e45c3de927e78d50f25cf02fc3a83
https://pub.dzne.de/record/141019
https://pub.dzne.de/record/141019
Autor:
Yun Zhang, Adrian W. Moore, Julia Nagel, Gaia Tavosanis, Caroline Delandre, Friedrich Forstner
Publikováno v:
Development 139(16), 2999-3009 (2012). doi:10.1242/dev.077800
The branched morphology of dendrites represents a functional hallmark of distinct neuronal types. Nonetheless, how diverse neuronal class-specific dendrite branches are generated is not understood. We investigated specific classes of sensory neurons