Zobrazeno 1 - 2
of 2
pro vyhledávání: '"metabolism [N-Acetylglucosaminyltransferases]"'
Autor:
Mahkameh Abeditashi, Katherine J. Robinson, Jacob Helm, Thorsten Schmidt, Olaf Riess, Jonasz J. Weber, Zinah Wassouf, Stefan Hauser, Ludger Schöls, Jana Schmidt, Maxinne Watchon, Angela S. Laird, Priscila Pereira Sena, Jeannette Hübener-Schmid
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 118(47), e2025810118 (2021). doi:10.1073/pnas.2025810118
Aberrant O-GlcNAcylation, a protein posttranslational modification defined by the O-linked attachment of the monosaccharide N-acetylglucosamine (O-GlcNAc), has been implicated in neurodegenerative diseases. However, although many neuronal proteins ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850e1e42f506abfc7e7a1e2276b8f487
https://doi.org/10.1073/pnas.2025810118
https://doi.org/10.1073/pnas.2025810118
Autor:
Mkhikian, Haik, Grigorian, Ani, Li, Carey F, Chen, Hung-Lin, Newton, Barbara, Zhou, Raymond W, Beeton, Christine, Torossian, Sevan, Tatarian, Gevork Grikor, Lee, Sung-Uk, Lau, Ken, Walker, Erin, Siminovitch, Katherine A, Chandy, K George, Yu, Zhaoxia, Dennis, James W, Demetriou, Michael
Publikováno v:
Mkhikian, Haik; Grigorian, Ani; Li, Carey F; Chen, Hung-Lin; Newton, Barbara; Zhou, Raymond W; et al.(2011). Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis.. Nature communications, 2, 334-3334. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/1rk7s5qv
How environmental factors combine with genetic risk at the molecular level to promote complex trait diseases such as multiple sclerosis (MS) is largely unknown. In mice, N-glycan branching by the Golgi enzymes Mgat1 and/or Mgat5 prevents T cell hyper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::18b83e29a88f380b34528c0bc82ba557
http://www.escholarship.org/uc/item/1rk7s5qv
http://www.escholarship.org/uc/item/1rk7s5qv
