Výsledky vyhledávání - "metabolism [Mechanistic Target of Rapamycin Complex 2]"

Loss of mTORC2-induced metabolic reprogramming in monocytes uncouples migration and maturation from production of proinflammatory mediators

Autor: Lamya Yamani, Frances R. Balkwill, Federica M. Marelli-Berg, Juho Vuononvirta, Melania Capasso, Eleanor J. Ward, Suchita Nadkarni, Maryam Jangani

Publikováno v: Journal of leukocyte biology 111(5), 967-980 (2022). doi:10.1002/JLB.1A0920-588R

Monocyte migration to the sites of inflammation and maturation into macrophages are key steps for their immune effector function. Here, we show that mechanistic target of rapamycin complex 2 (mTORC2)-dependent Akt activation is instrumental for metab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c37bac8cd8d674c7b85b94c49a2a57
https://pub.dzne.de/record/162927

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