Zobrazeno 1 - 2
of 2
pro vyhledávání: '"metabolism [Heterogeneous Nuclear Ribonucleoprotein A1]"'
Autor:
Zhanyun Fan, Tarun V. Kamath, Anthony A. Hyman, Charles R. Vanderburg, J. Paul Taylor, Bahareh Eftekharzadeh, Amandine Molliex, Bradley T. Hyman, Katarzyna Marta Zoltowska, Katharina Tepper, Rachel E. Bennett, Allyson D. Roe, Pawel R. Laskowski, Susanne Wegmann, Amayra Hernández-Vega, Daniel J. Müller, Caitlin Commins, Eckhard Mandelkow, Simon Dujardin, Danny MacKenzie
Publikováno v:
EMBO Journal
The EMBO Journal
The EMBO journal 37(7), e98049 (2018). doi:10.15252/embj.201798049
The EMBO Journal
The EMBO journal 37(7), e98049 (2018). doi:10.15252/embj.201798049
The transition between soluble intrinsically disordered tau protein and aggregated tau in neurofibrillary tangles in Alzheimer's disease is unknown. Here, we propose that soluble tau species can undergo liquid–liquid phase separation (LLPS) under c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9167a871aa08aef02aee28352f25acf4
https://hdl.handle.net/21.11116/0000-0003-53A6-421.11116/0000-0003-53A8-2
https://hdl.handle.net/21.11116/0000-0003-53A6-421.11116/0000-0003-53A8-2
Autor:
Davidson, Yvonne S, Flood, Louis, Pickering-Brown, Stuart, Haass, Christian, Lashley, Tammaryn, Mann, David M A, Robinson, Andrew C, Nihei, Yoshihiro, Mori, Kohji, Rollinson, Sara, Richardson, Anna, Benson, Bridget C, Jones, Matthew, Snowden, Julie S
Publikováno v:
Acta Neuropathologica Communications
Davidson, Y S, Flood, L, Robinson, A C, Nihei, Y, Mori, K, Rollinson, S, Richardson, A, Benson, B C, Jones, M, Snowden, J S, Pickering-Brown, S, Haass, C, Lashley, T & Mann, D M A 2017, ' Heterogeneous ribonuclear protein A3 (hnRNP A3) is present in dipeptide repeat protein containing inclusions in Frontotemporal Lobar Degeneration and Motor Neurone disease associated with expansions in C9orf72 gene ', Acta Neuropathologica Communications, vol. 5, no. 1, pp. 31 . https://doi.org/10.1186/s40478-017-0437-5
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-10 (2017)
Acta Neuropathologica Communications 5(1), 31 (2017). doi:10.1186/s40478-017-0437-5
Davidson, Y S, Flood, L, Robinson, A C, Nihei, Y, Mori, K, Rollinson, S, Richardson, A, Benson, B C, Jones, M, Snowden, J S, Pickering-Brown, S, Haass, C, Lashley, T & Mann, D M A 2017, ' Heterogeneous ribonuclear protein A3 (hnRNP A3) is present in dipeptide repeat protein containing inclusions in Frontotemporal Lobar Degeneration and Motor Neurone disease associated with expansions in C9orf72 gene ', Acta Neuropathologica Communications, vol. 5, no. 1, pp. 31 . https://doi.org/10.1186/s40478-017-0437-5
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-10 (2017)
Acta Neuropathologica Communications 5(1), 31 (2017). doi:10.1186/s40478-017-0437-5
Frontotemporal Lobar Degeneration (FTLD) encompasses certain related neurodegenerative disorders which alter behaviour, personality and language. Heterogeneous ribonuclear proteins (hnRNPs) maintain RNA metabolism and changes in their function may un