Zobrazeno 1 - 10
of 39
pro vyhledávání: '"metabolism [Green Fluorescent Proteins]"'
Autor:
Ewa Baczynska, David Baidoe-Ansah, Jakub Wlodarczyk, Luisa Strackeljan, Alexander Dityatev, Rahul Kaushik, Carla Cangalaya
Publikováno v:
Cells
Cells 10(8), 1862 (2021). doi:10.3390/cells10081862
Cells, Vol 10, Iss 1862, p 1862 (2021)
Volume 10
Issue 8
Cells 10(8), 1862 (2021). doi:10.3390/cells10081862
Cells, Vol 10, Iss 1862, p 1862 (2021)
Volume 10
Issue 8
The extracellular matrix (ECM) plays a key role in synaptogenesis and the regulation of synaptic functions in the central nervous system. Recent studies revealed that in addition to dopaminergic and serotoninergic neuromodulatory systems, microglia a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769067983a625aeb97d4ae997b8c1323
https://pubmed.ncbi.nlm.nih.gov/34440631
https://pubmed.ncbi.nlm.nih.gov/34440631
Autor:
Marion Mathelié-Guinlet, Yves F. Dufrêne, Rodrigo Gallardo, Emiel Michiels, Frederic Rousseau, Shu Liu, Ina Vorberg, Joost Schymkowitz, Nikolaos N. Louros
Publikováno v:
Cell Reports, Vol 30, Iss 8, Pp 2834-2845.e3 (2020)
Cell Reports
Cell Reports, Vol. 30, no.8, p. 2834-2845.e3 (2020)
Cell reports 30(8), 2834-2845.e3 (2020). doi:10.1016/j.celrep.2020.01.098
Cell Reports
Cell Reports, Vol. 30, no.8, p. 2834-2845.e3 (2020)
Cell reports 30(8), 2834-2845.e3 (2020). doi:10.1016/j.celrep.2020.01.098
Summary Prions of lower eukaryotes are self-templating protein aggregates with cores formed by parallel in-register beta strands. Short aggregation-prone glutamine (Q)- and asparagine (N)-rich regions embedded in longer disordered domains have been p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90177fbece33ee911d50b113b49df567
https://lirias.kuleuven.be/handle/123456789/652026
https://lirias.kuleuven.be/handle/123456789/652026
Autor:
Jens Reimann, Rishibha Sachdev, Lydia Paulsen, Catharina Pleschka, Karin Kappes-Horn, Ina Vorberg, Bishwajit Kundu, Yvonne Duernberger, Philip Denner
Publikováno v:
Molecular Neurobiology
Molecular neurobiology 55(11), 8355-8373 (2018). doi:10.1007/s12035-018-0997-9
Molecular neurobiology 55(11), 8355-8373 (2018). doi:10.1007/s12035-018-0997-9
Sporadic inclusion body myositis (sIBM) is the most prevalent acquired muscle disorder in the elderly with no defined etiology or effective therapy. Endoplasmic reticulum stress and deposition of myostatin, a secreted negative regulator of muscle gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd45497362010b92d5950885cb52553
https://doi.org/10.1007/s12035-018-0997-9
https://doi.org/10.1007/s12035-018-0997-9
Autor:
Lilian Staerck, Golo Kronenberg, Helmut Kettenmann, Friederike Klempin, Stephanie Wegner, Karen Gertz, Wolfgang Uckert, Nadine Richter, Matthias Endres, Ria Uhlemann, Susanne A. Wolf
Publikováno v:
Acta neuropathologica 135(4), 551-568 (2017). doi:10.1007/s00401-017-1795-6
After stroke, macrophages in the ischemic brain may be derived from either resident microglia or infiltrating monocytes. Using bone marrow (BM)-chimerism and dual-reporter transgenic fate mapping, we here set out to delimit the responses of either ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a437546f0aa140714a4c266aabf7cc
https://doi.org/10.1007/s00401-017-1795-6
https://doi.org/10.1007/s00401-017-1795-6
Autor:
Ayse Ulusoy, Robert J. Phillips, Michael Helwig, Terry L. Powley, Michael Klinkenberg, Donato A. Di Monte
Publikováno v:
Acta neuropathologica 133(3), 381-393 (2016). doi:10.1007/s00401-016-1661-y
Detection of α-synuclein lesions in peripheral tissues is a feature of human synucleinopathies of likely pathogenetic relevance and bearing important clinical implications. Experiments were carried out to elucidate the relationship between α-synucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a040d3e25f412dd8efce2d1f9fc4109
https://doi.org/10.1007/s00401-016-1661-y
https://doi.org/10.1007/s00401-016-1661-y
Autor:
Elena Montagna, Carmelo Sgobio, Sophie Crux, Julia Herber, Gerhard Wanner, Stefan F. Lichtenthaler, Sabina Tahirovic, Petar Marinković, Alessio Colombo, Ulrike Müller, Jochen Herms, Manja Luckner
Publikováno v:
Glia 67(5), 985-998 (2019). doi:10.1002/glia.23584
The investigation of amyloid precursor protein (APP) has been mainly confined to its neuronal functions, whereas very little is known about its physiological role in astrocytes. Astrocytes exhibit a particular morphology with slender extensions protr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8141c8de7e3a0c3a1177248b07a50a53
Autor:
Stefan Kindler, Charlotte J. Thynne, Craig C. Garner, Kevin Lee, Johanna M. Montgomery, Claudia Schob, Magali H. Arons, Sally A. Kim
Publikováno v:
The journal of neuroscience 36(35), 9124-9134 (2016). doi:10.1523/JNEUROSCI.0116-16.2016
Shank3 is a multidomain scaffold protein localized to the postsynaptic density of excitatory synapses. Functional studies in vivo and in vitro support the concept that Shank3 is critical for synaptic plasticity and the trans-synaptic coupling between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1aad45aa2a339038bd9f0a42ce5e83d
https://doi.org/10.1523/jneurosci.0116-16.2016
https://doi.org/10.1523/jneurosci.0116-16.2016
Autor:
Muhammad Ichwan, Gerd Kempermann, Alex M. Sykes, Susann Ruhwald, Tara L. Walker, Steffen Vogler, Rupert W. Overall, Klaus Fabel, Daniela Lasse
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 6, Iss 4, Pp 552-565 (2016)
Stem cell reports 6(4), 552-565 (2016). doi:10.1016/j.stemcr.2016.03.002
Stem Cell Reports, Vol 6, Iss 4, Pp 552-565 (2016)
Stem cell reports 6(4), 552-565 (2016). doi:10.1016/j.stemcr.2016.03.002
Summary Here, we show that the lysophosphatidic acid receptor 1 (LPA1) is expressed by a defined population of type 1 stem cells and type 2a precursor cells in the adult mouse dentate gyrus. LPA1, in contrast to Nestin, also marks the quiescent stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70674d519c5669d2edd766089c10578a
Autor:
Christian Steinhäuser, Peter Bedner, Monika Plescher, Gerald Seifert, Jan N. Hansen, Annett Halle
Publikováno v:
Glia 66(7), 1464-1480 (2018). doi:10.1002/glia.23318
Microglia, the central nervous system resident innate immune cells, cluster around Aβ plaques in Alzheimer's disease (AD). The activation phenotype of these plaque-associated microglial cells, and their differences to microglia distant to Aβ plaque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0878bbd2890adcd02fe378cc02bf0954
Publikováno v:
New York, NY : Springer New York, Methods in Molecular Biology 1714, 97-117 (2018). doi:10.1007/978-1-4939-7519-8_7
Innate Immune Activation / De Nardo, Dominic (Editor) ; New York, NY : Springer New York, 2018, Chapter 7 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-4939-7518-1=978-1-4939-7519-8 ; doi:10.1007/978-1-4939-7519-8
Methods in Molecular Biology ISBN: 9781493975181
Innate Immune Activation / De Nardo, Dominic (Editor) ; New York, NY : Springer New York, 2018, Chapter 7 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-4939-7518-1=978-1-4939-7519-8 ; doi:10.1007/978-1-4939-7519-8
Methods in Molecular Biology ISBN: 9781493975181
Innate immune cells are notoriously difficult to transfect; however, retroviruses can be used to stably integrate genes of interest into the host genome of primary or immortalized immune cells resulting in the generation of reporter cells. Here, we p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a54fd648f0b834f0e05b8967d2ec91b