Zobrazeno 1 - 10
of 12
pro vyhledávání: '"metabolism [Embryonic Stem Cells]"'
Autor:
Langkabel, Jan, Horne, Arik, Bonaguro, Lorenzo, Holsten, Lisa, Hesse, Tatiana, Knaus, Alexej, Riedel, Yannick, Becker, Matthias, Händler, Kristian, Elmzzahi, Tarek, Bassler, Kevin, Reusch, Nico, Yeghiazarian, Leon Harootoonovtch, Pecht, Tal, Saglam, Adem, Ulas, Thomas, Aschenbrenner, Anna C., Kaiser, Franziska, Kubaczka, Caroline, Schultze, Joachim L., Schorle, Hubert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications 12(1), 7322 (2021). doi:10.1038/s41467-021-27586-w
Nature Communications
Nature Communications 12(1), 7322 (2021). doi:10.1038/s41467-021-27586-w
Blastocyst-derived stem cell lines were shown to self-organize into embryo-like structures in 3D cell culture environments. Here, we provide evidence that embryo-like structures can be generated solely based on transcription factor-mediated reprogram
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c76882489a9ac948b288557830b06ba4
https://doaj.org/article/4777dcfcfbcb4d98ae83f5dc3f98bef3
https://doaj.org/article/4777dcfcfbcb4d98ae83f5dc3f98bef3
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 2 (2021)
Disease models & mechanisms 14(2), dmm047803 (2021). doi:10.1242/dmm.047803
Dis. Model. Mech. 14:dmm047803 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease models & mechanisms 14(2), dmm047803 (2021). doi:10.1242/dmm.047803
Dis. Model. Mech. 14:dmm047803 (2021)
Disease Models & Mechanisms
article-version (VoR) Version of Record
Gene trapping is a high-throughput approach that has been used to introduce insertional mutations into the genome of mouse embryonic stem (ES) cells. It is performed with generic gene trap vectors that simultaneously mutate and report the expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126c1985eeec2ee888a6b678f6813bf7
http://dmm.biologists.org/content/14/2/dmm047803
http://dmm.biologists.org/content/14/2/dmm047803
Autor:
Jochen Roeper, Niklas Kleinenkuhnen, Malte Stockebrand, Marta Florio, Anna Katharina Schlusche, Igor Jakovcevski, Sabine Ulrike Vay, Steffi Sandke, Dirk Isbrandt, Achim Tresch, Wieland B. Huttner, Rafael Campos-Martin, Maria Adele Rueger
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 118(35), e2009393118 (2021). doi:10.1073/pnas.2009393118
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
The development of the cerebral cortex relies on the controlled division of neural stem and progenitor cells. The requirement for precise spatiotemporal control of proliferation and cell fate places a high demand on the cell division machinery, and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a71eaa9257832f436b89f3211d3ea06
https://pub.dzne.de/record/162815
https://pub.dzne.de/record/162815
Autor:
Tao Deng, Shaofei Zhang, Valerie Gailus-Durner, Helmut Fuchs, Lore Becker, Martin Hrabé de Angelis, Wolfgang Wurst, Yuri V. Postnikov, Ildiko Racz, Lillian Garrett, Michael Bustin, Sabine M. Hölter
Publikováno v:
Nucleic acids symposium series 45(6), 3031-3045 (2016). doi:10.1093/nar/gkw1222
Nucleic Acids Research
Nucleic Acids Res. 45, 3031-3045 (2017)
ResearcherID
Nucleic Acids Research
Nucleic Acids Res. 45, 3031-3045 (2017)
ResearcherID
An interplay between the nucleosome binding proteins H1 and HMGN is known to affect chromatin dynamics, but the biological significance of this interplay is still not clear. We find that during embryonic stem cell differentiation loss of HMGNs leads
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264cb447a55432a401fec800e538b40b
Autor:
Wolfgang Wurst, Luca Giovanni Di Giovannantonio, Dario Acampora, Michela Di Salvio, Antonio Simeone, Nilima Prakash, Daniela Omodei, Alessandra Pierani
Publikováno v:
Development 141, 377-388 (2014)
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2014, 141 (2), pp.377-88. ⟨10.1242/dev.102954⟩
Development 141(2), 377-388 (2013). doi:10.1242/dev.102954
Development (Dublin, 1970) 141 (2014): 377. doi:10.1242/dev.102954
info:cnr-pdr/source/autori:Di Giovannantonio LG, Di Salvio M, Omodei D, Prakash N, Wurst W, Pierani A, Acampora D, Simeone A./titolo:Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity./doi:10.1242%2Fdev.102954/rivista:Development (Dublin, 1970)/anno:2014/pagina_da:/pagina_a:377/intervallo_pagine:377/volume:141
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2014, 141 (2), pp.377-88. ⟨10.1242/dev.102954⟩
Development
Development (Dublin, 1970) 141 (2014): 377. doi:10.1242/dev.102954
info:cnr-pdr/source/autori:Di Giovannantonio LG, Di Salvio M, Omodei D, Prakash N, Wurst W, Pierani A, Acampora D, Simeone A./titolo:Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity./doi:10.1242%2Fdev.102954/rivista:Development (Dublin, 1970)/anno:2014/pagina_da:/pagina_a:377/intervallo_pagine:377/volume:141
International audience; During embryonic development, the rostral neuroectoderm is regionalized into broad areas that are subsequently subdivided into progenitor compartments with specialized identity and fate. These events are controlled by signals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddcf08112bfaac466d50bdaef926928
https://doi.org/10.1242/dev.102954
https://doi.org/10.1242/dev.102954
Publikováno v:
Amyotrophic lateral sclerosis & frontotemporal degeneration 16(7-8), 431-441 (2015). doi:10.3109/21678421.2015.1055275
TAR DNA-binding protein 43 (TDP-43) and fused in sarcoma (FUS) were recently found to cause familial and sporadic amyotrophic lateral sclerosis (ALS). The mechanisms by which mutations within these genes cause ALS are not understood. We established m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01c2623b0d27e3783ea1c973dd844e4
https://pub.dzne.de/record/138215
https://pub.dzne.de/record/138215
Autor:
Caroline Schall, Wolfgang Wurst, Andrew J. Washkowitz, Thomas Floss, Jesse Mager, Virginia E. Papaioannou, Kun Zhang
Publikováno v:
Development 142(1), 31-40 (2014). doi:10.1242/dev.111104
Development 142, 31-40 (2015)
Development 142, 31-40 (2015)
The maintenance and control of pluripotency is of great interest in stem cell biology. The dual specificity T-box/basic-helix-loop-helix-zipper transcription factor Mga is expressed in the pluripotent cells of the inner cell mass (ICM) and epiblast o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f586061fed95823a6462228ecf3f93c9
Autor:
Nicolas De Jay, Leonie G. Mikael, Steffen Albrecht, Nisreen Samir Ibrahim, Ashot S. Harutyunyan, Robin Ketteler, Javier Herrero, Nada Jabado, Claudia L. Kleinman, Pirasteh Pahlavan, Antonella Riccio, Sebastian Brandner, Angela Richard-Londt, Joana R. Costa, Nicola Maestro, Paolo Salomoni, Manav Pathania, Ying Zhang, Steven Hébert, Sima Khazaei, Stephen Henderson, Justyna Nitarska
Publikováno v:
Cancer cell 32(5), 684-700.e9 (2017). doi:10.1016/j.ccell.2017.09.014
Gain-of-function mutations in histone 3 (H3) variants are found in a substantial proportion of pediatric high-grade gliomas (pHGG), often in association with TP53 loss and platelet-derived growth factor receptor alpha (PDGFRA) amplification. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860ff2fffb25beae3b50956746caf28d
https://doi.org/10.1016/j.ccell.2017.09.014
https://doi.org/10.1016/j.ccell.2017.09.014
Autor:
Martin J. Pfeiffer, Nicola Crosetto, Nicole Baeumer, Sebastian T. Balbach, Michele Boiani, Yogesh Paudel, Hannes C.A. Drexler, Georg Fuellen, Marcin Siatkowski
Publikováno v:
Journal of proteome research 10(5), 2140-2153 (2011). doi:10.1021/pr100706k
Journal of Proteome Research, 10(5), 2140-2153
Journal of Proteome Research 10 (2011) 5
Journal of Proteome Research, 10(5), 2140-2153
Journal of Proteome Research 10 (2011) 5
The oocyte is the only cell of the body that can reprogram transplanted somatic nuclei and sets the gold standard for all reprogramming methods. Therefore, an in-depth characterization of its proteome holds promise to advance our understanding of rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db71ae5c953efa6e713ee7f4268c5be8
https://pub.dzne.de/record/136224
https://pub.dzne.de/record/136224
Publikováno v:
Methods 53(4), 430-436 (2011). doi:10.1016/j.ymeth.2010.12.015
Gene silencing by RNA interference (RNAi) has become a routine method for extracting function from the mammalian genome. Short hairpin (sh) RNAs expressed from stably integrated vectors mediate RNAi both in cultured cells and mice and present therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969738c3594802112742dce07035bb50
https://pubmed.ncbi.nlm.nih.gov/21184828
https://pubmed.ncbi.nlm.nih.gov/21184828