Zobrazeno 1 - 2
of 2
pro vyhledávání: '"metabolism [DNA Repair Enzymes]"'
Autor:
Bertolini, F., Zunarelli, E., Baraldi, C., Valentini, A., Giovane, C. D., Depenni, R., Falasca, A., Giacobazzi, P., Malagoli, M., Meletti, Stefano, Fontana, A., Conte, P., Oncologico, G. N.
Publikováno v:
Tumori. 98(6)
Aims and background Recursive partioning analysis (RPA) is commonly used to define the stratification of patients with glioblastoma. Epigenetic silencing of the O6-methylguanine methyltransferase (MGMT) gene by promoter methylation plays an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b319cb2b8e75998bf98c18d99626a5a4
https://pubmed.ncbi.nlm.nih.gov/23389363
https://pubmed.ncbi.nlm.nih.gov/23389363
Autor:
Katja Sträßer, Sophia Hartung, Carolin Möckel, Emanuel Clausing, Derk J. Bemeleit, María Lucas, Christian B. Schiller, Alexandra Schele, Karl-Peter Hopfner, Katja Lammens, Christof Angermüller, Johannes Söding
Publikováno v:
Cell
Cell 145, 54-66 (2011). doi:10.1016/j.cell.2011.02.038
Cell 145, 54-66 (2011). doi:10.1016/j.cell.2011.02.038
Summary The MR ( M re11 nuclease and R ad50 ABC ATPase) complex is an evolutionarily conserved sensor for DNA double-strand breaks, highly genotoxic lesions linked to cancer development. MR can recognize and process DNA ends even if they are blocked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e9c4a2916ab3742bb61701d052675a