Zobrazeno 1 - 10
of 12
pro vyhledávání: '"metabolism [Creatine]"'
Autor:
Jan Traub, Markus Otto, Roxane Sell, Dennis Göpfert, György Homola, Petra Steinacker, Patrick Oeckl, Caroline Morbach, Stefan Frantz, Mirko Pham, Stefan Störk, Guido Stoll, Anna Frey
Publikováno v:
Alzheimer's research & therapy 14(1), 149 (2022). doi:10.1186/s13195-022-01087-4
Background Chronic heart failure (HF) is known to increase the risk of developing Alzheimer’s dementia significantly. Thus, detecting and preventing mild cognitive impairment, which is common in patients with HF, is of great importance. Serum bioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aaa1e5530daa8ec7736db44881d7308
https://pub.dzne.de/record/165334
https://pub.dzne.de/record/165334
Autor:
Chi-Un Choe, Christian Gerloff, Soenke Hornig, Axel Neu, Dirk Isbrandt, D. Tsikas, Ali Sasani, Edzard Schwedhelm
Publikováno v:
Amino Acids
Amino acids 52(6-7), 1067-1069 (2020). doi:10.1007/s00726-020-02865-w
Amino acids 52(6-7), 1067-1069 (2020). doi:10.1007/s00726-020-02865-w
Our study evaluated the effect of creatine and homoarginine in AGAT- and GAMT-deficient mice after simvastatin exposure. Balestrino and Adriano suggest that guanidinoacetate might explain the difference between AGAT- and GAMT-deficient mice in simvas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec191946a519554760ce53c5c8647712
https://doi.org/10.1007/s00726-020-02865-w
https://doi.org/10.1007/s00726-020-02865-w
Autor:
Tobias Lindner, Jan Stenzel, Angela Kuhla, Claire Rühlmann, Bernd J. Krause, Stefan J. Teipel, Brigitte Vollmar, Nicole Power Guerra, Luisa Müller
Publikováno v:
Nutrients
Nutrients 13(3), 985-(2021). doi:10.3390/nu13030985
Volume 13
Issue 3
Nutrients, Vol 13, Iss 985, p 985 (2021)
Nutrients 13(3), 985-(2021). doi:10.3390/nu13030985
Volume 13
Issue 3
Nutrients, Vol 13, Iss 985, p 985 (2021)
Caloric restriction (CR) slows the aging process, extends lifespan, and exerts neuroprotective effects. It is widely accepted that CR attenuates β-amyloid (Aβ) neuropathology in models of Alzheimer’s disease (AD) by so-far unknown mechanisms. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::099afc6a9d10e3ab4f15075cc70faab1
https://pubmed.ncbi.nlm.nih.gov/33803798
https://pubmed.ncbi.nlm.nih.gov/33803798
Autor:
Ricarda Grzybowski, Erik Hanff, Rainer H. Böger, D. Tsikas, Kathrin Cordts, Christian Gerloff, Axel Neu, Ali Sasani, Chi-Un Choe, Dirk Isbrandt, Sönke Hornig, Edzard Schwedhelm
Publikováno v:
Amino acids 52(1), 73-85 (2019). doi:10.1007/s00726-019-02812-4
Statin-induced myopathy affects more than 10 million people worldwide. But discontinuation of statin treatment increases mortality and cardiovascular events. Recently, l-arginine:glycine amidinotransferase (AGAT) gene was associated with statin-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe4cb8e5eadb2c2955bef83ca8dd4f8
Autor:
Angela Kuhla, Claire Rühlmann, Tobias Lindner, Stefan Polei, Stefan Hadlich, Bernd J. Krause, Brigitte Vollmar, Stefan J. Teipel
Publikováno v:
NeuroImage : Clinical
NeuroImage: Clinical 15, 581-586 (2017). doi:10.1016/j.nicl.2017.06.009
NeuroImage: Clinical, Vol 15, Iss, Pp 581-586 (2017)
NeuroImage: Clinical 15, 581-586 (2017). doi:10.1016/j.nicl.2017.06.009
NeuroImage: Clinical, Vol 15, Iss, Pp 581-586 (2017)
Transgenic animal models of Aβ pathology provide mechanistic insight into some aspects of Alzheimer disease (AD) pathology related to Aβ accumulation. Quantitative neuroimaging is a possible aid to improve translation of mechanistic findings in tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::377f7cd048cbd83f9f7ffadbf6a42f4b
http://europepmc.org/articles/PMC5476467
http://europepmc.org/articles/PMC5476467
A spectroscopic approach toward depression diagnosis: local metabolism meets functional connectivity
Autor:
Adam Safron, Liliana Ramona Demenescu, Martin Walter, Lejla Colic, Meng Li, Coraline D. Metzger, Shijia Li, Bharat B. Biswal
Publikováno v:
European Archives of Psychiatry and Clinical Neuroscience
European archives of psychiatry and clinical neuroscience 267(2), 95-105 (2016). doi:10.1007/s00406-016-0726-1
European archives of psychiatry and clinical neuroscience 267(2), 95-105 (2016). doi:10.1007/s00406-016-0726-1
Abnormal anterior insula (AI) response and functional connectivity (FC) is associated with depression. In addition to clinical features, such as severity, AI FC and its metabolism further predicted therapeutic response. Abnormal FC between anterior c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd4fed6583d069fd1267b20c128cd31
https://doi.org/10.1007/s00406-016-0726-1
https://doi.org/10.1007/s00406-016-0726-1
Autor:
Tanja Schmitz-Hübsch, Sarah Doss, Jan Leo Rinnenthal, Matthias Endres, Sebastian Papazoglou, Jens Würfel, Alexander U. Brandt, Silke Lux, Stephan Maul, Martina Minnerop, Friedemann Paul, Thomas Klockgether
Publikováno v:
Journal of neurology 262(8), 1927-1935 (2015). doi:10.1007/s00415-015-7788-2
Autosomal dominant ataxia type 14 (SCA14) is a rare usually adult-onset progressive disorder with cerebellar neurodegeneration caused by mutations in protein kinase C gamma. We set out to examine cerebellar and extracerebellar neurochemical changes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f341c1a1ebfc7b32baa7cdc1a0c14469
https://doi.org/10.1007/s00415-015-7788-2
https://doi.org/10.1007/s00415-015-7788-2
Autor:
Jörg Magerkurth, Kathrin Brockmann, Ulrich Pilatus, Karin Srulijes, Daniela Berg, Elke Hattingen, Thomas Gasser, Ilona Csoti, Caroline Denise Merten, Simon Baudrexel, Ruediger Hilker, Claudia Schulte, Ann-Kathrin Hauser
Publikováno v:
Neurology; Vol 79
Neurology 79(3), 213-220 (2012). doi:10.1212/WNL.0b013e31825dd369
Web of Science
Neurology
Neurology 79(3), 213-220 (2012). doi:10.1212/WNL.0b013e31825dd369
Web of Science
Neurology
Objective: To elucidate possible mechanisms leading to neurodegeneration in patients with glucocerebrosidase ( GBA )–associated Parkinson disease (PD) using combined proton ( 1 H) and phosphorus ( 31 P) magnetic resonance spectroscopic imaging (MRS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103acbdd49515aa1820585e1edd9e2f4
Publikováno v:
Brain Research. Molecular Brain Research, vol. 91, no. 1-2, pp. 189-195
l -Arginine is a substrate for the synthesis of proteins, nitric oxide (NO), creatine, urea, proline, glutamate, polyamines and agmatine. In the central nervous system (CNS), arginine is extracted from the blood and exchanged by cells through carrier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61df736c5d8b3c83f851fb2c676ff04
https://doi.org/10.1016/s0169-328x(01)00113-9
https://doi.org/10.1016/s0169-328x(01)00113-9
Publikováno v:
European radiology 21(9), 1962-1969 (2011). doi:10.1007/s00330-011-2123-5
To investigate the substantia nigra in patients with Parkinson’s disease three-dimensional magnetic resonance spectroscopic imaging with high spatial resolution at 3 Tesla was performed. Regional variations of spectroscopic data between the rostral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdbb966dea9bfce4846c655af3e56a75
https://pubmed.ncbi.nlm.nih.gov/21484351
https://pubmed.ncbi.nlm.nih.gov/21484351