Výsledky vyhledávání - "metabolism [Connexin 43]"

Connexin43 inhibition attenuated dopaminergic neuronal loss in the lipopolysaccharide-induced mice model of Parkinson's disease

Autor: Yujia Zhao, Yuze Qi, Qingru Li, Huihui Quan, Dan Liu, Hui Zhou

Publikováno v: Neuroscience letters 771, 136471 (2022). doi:10.1016/j.neulet.2022.136471

Studies using in vitro Parkinson's disease (PD) models have found that lipopolysaccharide (LPS) induced reduction of connexin 43 (Cx43) gap junction communication and elevation of hemichannel function, which could cause neurotoxicity directly and ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5747b2eb7ca27f8960d4853cef325ae
https://pub.dzne.de/record/163619

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RAKERS et al

Autor: Cordula Rakers, Matthias Schmid, Gabor C. Petzold

Publikováno v: Glia 65(9), 1550-1561 (2017). doi:10.1002/glia.23183
Glia

Stroke is one of the leading causes of death and long-term disability. In the penumbra, that is, the area surrounding the infarct core, peri-infarct depolarizations (PIDs) are accompanied by strong intracellular calcium elevations in astrocytes and n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588e1d215ae13eaf7c5463da0f71b6aa
https://doi.org/10.1002/glia.23183

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Subcellular reorganization and altered phosphorylation of the astrocytic gap junction protein connexin43 in human and experimental temporal lobe epilepsy

Autor: Christian Steinhäuser, Michel K. Herde, Martin K. Schwarz, Tingsong Li, Peter Bedner, Tushar Deshpande, Albert J. Becker, Hartmut Vatter, Christian Henneberger

Publikováno v: Glia 65(11), 1809-1820 (2017). doi:10.1002/glia.23196

Dysfunctional astrocytes are increasingly recognized as key players in the development and progression of mesial temporal lobe epilepsy (MTLE). One of the dramatic changes astrocytes undergo in MTLE with hippocampal sclerosis (HS) is loss of gap junc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a52549dc975ec149670fe2c64680ce
https://pubmed.ncbi.nlm.nih.gov/28795432

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Stroke target identification guided by astrocyte transcriptome analysis

Autor: Thomas Ulas, Toni Schumacher, Walker S. Jackson, Khalid Tai, Melvin Schleif, Joachim L. Schultze, Cordula Rakers, Santiago Valle Torres, Hana Matuskova, Kristian Händler, Gabor C. Petzold, Nelli Blank

Publikováno v: Glia 67(4), 619-633 (2018). doi:10.1002/glia.23544
Glia

Astrocytes support normal brain function, but may also contribute to neurodegeneration when they become reactive under pathological conditions such as stroke. However, the molecular underpinnings of this context‐dependent interplay between benefici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5acfbd175b5f6f012786e43087d00720

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