Zobrazeno 1 - 10
of 93
pro vyhledávání: '"metabolism, Inflammation"'
Autor:
Giovanni Adami, Giovanni Orsolini, Maurizio Rossini, Anna Fratucello, Angelo Fassio, Ombretta Viapiana, Elena Fracassi, Riccardo Bixio, Davide Gatti
Publikováno v:
BMC Rheumatology, Vol 8, Iss 1, Pp 1-10 (2024)
Key-points Bone turnover makers (P1nP, B-ALP, CTX), bone modulators (Dkk1, sclerostin) and BMD were measured prospectively in rheumatoid arthritis patients treated with tofacitinib. Sclerostin increased significantly after treatment with tofacitinib,
Externí odkaz:
https://doaj.org/article/d35e056c86f946fa8396bd695a1939ef
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Dirk Reinhold, Vadim Farztdinov, Yan Yan, Christian Meisel, Henrik Sadlowski, Joachim Kühn, Frank H. Perschel, Matthias Endres, Emrah Düzel, Stefan Vielhaber, Karina Guttek, Alexander Goihl, Morten Venø, Bianca Teegen, Winfried Stöcker, Paula Stubbemann, Florian Kurth, Leif E. Sander, Markus Ralser, Carolin Otto, Simon Streit, Sven Jarius, Klemens Ruprecht, Helena Radbruch, Jørgen Kjems, Michael Mülleder, Frank Heppner, Peter Körtvelyessy
Publikováno v:
Journal of neuroinflammation 20(1), 30 (2023). doi:10.1186/s12974-023-02711-2
Reinhold, D, Farztdinov, V, Yan, Y, Meisel, C, Sadlowski, H, Kühn, J, Perschel, F H, Endres, M, Düzel, E, Vielhaber, S, Guttek, K, Goihl, A, Venø, M, Teegen, B, Stöcker, W, Stubbemann, P, Kurth, F, Sander, L E, Ralser, M, Otto, C, Streit, S, Jarius, S, Ruprecht, K, Radbruch, H, Kjems, J, Mülleder, M, Heppner, F & Körtvelyessy, P 2023, ' The brain reacting to COVID-19 : analysis of the cerebrospinal fluid proteome, RNA and inflammation ', Journal of Neuroinflammation, vol. 20, 30 . https://doi.org/10.1186/s12974-023-02711-2
Reinhold, D, Farztdinov, V, Yan, Y, Meisel, C, Sadlowski, H, Kühn, J, Perschel, F H, Endres, M, Düzel, E, Vielhaber, S, Guttek, K, Goihl, A, Venø, M, Teegen, B, Stöcker, W, Stubbemann, P, Kurth, F, Sander, L E, Ralser, M, Otto, C, Streit, S, Jarius, S, Ruprecht, K, Radbruch, H, Kjems, J, Mülleder, M, Heppner, F & Körtvelyessy, P 2023, ' The brain reacting to COVID-19 : analysis of the cerebrospinal fluid proteome, RNA and inflammation ', Journal of Neuroinflammation, vol. 20, 30 . https://doi.org/10.1186/s12974-023-02711-2
Patients with COVID-19 can have a variety of neurological symptoms, but the active involvement of central nervous system (CNS) in COVID-19 remains unclear. While routine cerebrospinal fluid (CSF) analyses in patients with neurological manifestations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0f7975b03b3459d5464ae072593d9c
https://pub.dzne.de/record/253602
https://pub.dzne.de/record/253602
Autor:
Anna Ballweg, Carolin Klaus, Letizia Vogler, Sabrina Katzdobler, Karin Wind, Artem Zatcepin, Sibylle I. Ziegler, Birkan Secgin, Florian Eckenweber, Bernd Bohr, Alexander Bernhardt, Urban Fietzek, Boris-Stephan Rauchmann, Sophia Stoecklein, Stefanie Quach, Leonie Beyer, Maximilian Scheifele, Marcel Simmet, Emanuel Joseph, Simon Lindner, Isabella Berg, Norman Koglin, Andre Mueller, Andrew W. Stephens, Peter Bartenstein, Joerg C. Tonn, Nathalie L. Albert, Tania Kümpfel, Martin Kerschensteiner, Robert Perneczky, Johannes Levin, Lars Paeger, Jochen Herms, Matthias Brendel
Publikováno v:
Journal of neuroinflammation 20(1), 68 (2023). doi:10.1186/s12974-023-02749-2
Objectives Reactive gliosis is a common pathological hallmark of CNS pathology resulting from neurodegeneration and neuroinflammation. In this study we investigate the capability of a novel monoamine oxidase B (MAO-B) PET ligand to monitor reactive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ceba07853c46e5865cd9fcdc83eb87d
https://doi.org/10.1186/s12974-023-02749-2
https://doi.org/10.1186/s12974-023-02749-2
Autor:
Carla Cangalaya, Susanne Wegmann, Weilun Sun, Lisa Diez, Anna Gottfried, Karin Richter, Stoyan Stoyanov, Janelle Pakan, Klaus-Dieter Fischer, Alexander Dityatev
Publikováno v:
Brain, behavior and immunity 110, 245-259 (2023). doi:10.1016/j.bbi.2023.02.023
Remodeling of synapses by microglia is essential for synaptic plasticity in the brain. However, during neuroinflammation and neurodegenerative diseases, microglia can induce excessive synaptic loss, although the precise underlying mechanisms are unkn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac66009298a90af3f2be58a7d5ee1c9
https://pub.dzne.de/record/257592
https://pub.dzne.de/record/257592
Autor:
Veselin Grozdanov, Wolfgang Ruf, Karin M Danzer, Albert C. Ludolph, Jan Kassubek, Jochen H. Weishaupt, Divisha Bhatia
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-10 (2021)
Journal of neuroinflammation 18(1), 250 (2021). doi:10.1186/s12974-021-02296-8
Journal of Neuroinflammation
Journal of neuroinflammation 18(1), 250 (2021). doi:10.1186/s12974-021-02296-8
Journal of Neuroinflammation
The dysregulation of peripheral immunity in Parkinson’s Disease (PD) includes changes in both the relative numbers and gene expression of T cells. The presence of peripheral T-cell abnormalities in PD is well-documented, but less is known about the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8571ffe38097a0cc4e5ff5636f5244ca
https://doaj.org/article/1d5acbd09239467db660ff01bd6c3da2
https://doaj.org/article/1d5acbd09239467db660ff01bd6c3da2
Autor:
CATTANEO, LUCA
La messa in asciutta sta diventando una fase sempre più importante del ciclo di lattazione. Rappresenta un evento stressante per la bovina da latte perché comporta diversi cambiamenti nella gestione e nella fisiologia degli animali. Eventi infiamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1402::7f9c594e2055c85ac1e7a624ef9881a8
http://hdl.handle.net/10280/131852
http://hdl.handle.net/10280/131852
Autor:
Kenkhuis, B., Eekeren, M. van, Parfitt, D.A., Ariyurek, Y., Banerjee, P., Priller, J., Weerd, L. van der, Roon-Mom, W.M.C. van
Publikováno v:
Kenkhuis, B, Van Eekeren, M, Parfitt, D A, Ariyurek, Y, Banerjee, P, Priller, J, Van Der Weerd, L & Van Roon-mom, W M C 2022, ' Iron accumulation induces oxidative stress, while depressing inflammatory polarization in human iPSC-derived microglia ', Stem Cell Reports, vol. 17, no. 6, pp. 1351-1365 . https://doi.org/10.1016/j.stemcr.2022.04.006
Stem cell reports 17(6), 1351-1365 (2022). doi:10.1016/j.stemcr.2022.04.006
Stem Cell Reports, 17(6), 1351-1365. CELL PRESS
Stem cell reports 17(6), 1351-1365 (2022). doi:10.1016/j.stemcr.2022.04.006
Stem Cell Reports, 17(6), 1351-1365. CELL PRESS
Iron accumulation in microglia has been observed in Alzheimer's disease and other neurodegenerative disorders and is thought to contribute to disease progression through various mechanisms, including neuroinflammation. To study this interaction, we t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890fa94ccb87fb19d0cd2a7a92c1d8b8
https://www.pure.ed.ac.uk/ws/files/293610796/mmc5.pdf
https://www.pure.ed.ac.uk/ws/files/293610796/mmc5.pdf
Autor:
Sjors Maassen, Harry Warner, Melina Ioannidis, Jack Jansma, Hugo Markus, Sahar El Aidy, María-Dolores Chiara, Jose Luis Chiara, Larissa Maierhofer, Helen Weavers, Geert van den Bogaart
Publikováno v:
Free Radic. Biol. Med.
Weavers, H 2022, ' Mitochondrial interaction of fibrosis-protective 5-methoxy tryptophan enhances collagen uptake by macrophages. ', Free Radical Biology and Medicine, vol. 188, pp. 287-297 . https://doi.org/10.1016/j.freeradbiomed.2022.06.235
Free Radical Biology and Medicine, 188:202206235, 287-297. ELSEVIER SCIENCE INC
Weavers, H 2022, ' Mitochondrial interaction of fibrosis-protective 5-methoxy tryptophan enhances collagen uptake by macrophages. ', Free Radical Biology and Medicine, vol. 188, pp. 287-297 . https://doi.org/10.1016/j.freeradbiomed.2022.06.235
Free Radical Biology and Medicine, 188:202206235, 287-297. ELSEVIER SCIENCE INC
5-methoxy tryptophan (5-MTP) is an anti-fibrotic metabolite made by fibroblasts and epithelial cells, present in a micromolar concentrations in human blood, and is associated with the progression of fibrotic kidney disease, but the mechanism is uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f44cef9950069fdf609d546516fbfa
https://pubmed.ncbi.nlm.nih.gov/35753585
https://pubmed.ncbi.nlm.nih.gov/35753585
Autor:
Frederic Brosseron, Anne Maass, Luca Kleineidam, Kishore Aravind Ravichandran, Pablo García González, Róisín M. McManus, Christina Ising, Francesco Santarelli, Carl-Christian Kolbe, Lisa M. Häsler, Steffen Wolfsgruber, Marta Marquié, Mercè Boada, Adelina Orellana, Itziar de Rojas, Sandra Röske, Oliver Peters, Nicoleta-Carmen Cosma, Arda Cetindag, Xiao Wang, Josef Priller, Eike J. Spruth, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Jens Wiltfang, Björn H. Schott, Katharina Bürger, Daniel Janowitz, Martin Dichgans, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Goerss, Christoph Laske, Matthias H. Munk, Emrah Düzel, Renat Yakupov, Laura Dobisch, Coraline D. Metzger, Wenzel Glanz, Michael Ewers, Peter Dechent, John Dylan Haynes, Klaus Scheffler, Nina Roy, Ayda Rostamzadeh, Charlotte E. Teunissen, Natalie L. Marchant, Annika Spottke, Mathias Jucker, Eicke Latz, Michael Wagner, David Mengel, Matthis Synofzik, Frank Jessen, Alfredo Ramirez, Agustín Ruiz, Michael T. Heneka
Publikováno v:
the DELCODE study group 2022, ' Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease ', Neuron, vol. 110, no. 6, pp. 1009-1022.e4 . https://doi.org/10.1016/j.neuron.2021.12.016
Neuron, 110(6), 1009-1022.e4. Cell Press
Neuron 110(6), 1009-1022.e4 (2022). doi:10.1016/j.neuron.2021.12.016
Neuron, 110(6), 1009-1022.e4. Cell Press
Neuron 110(6), 1009-1022.e4 (2022). doi:10.1016/j.neuron.2021.12.016
There is an urgent need to improve the understanding of neuroinflammation in Alzheimer's disease (AD). We analyzed cerebrospinal fluid inflammatory biomarker correlations to brain structural volume and longitudinal cognitive outcomes in the DELCODE s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41ef513202d55323e4fa7d6c6fae0e9
https://research.vumc.nl/en/publications/7b3bd725-fd82-4214-85cb-1b6558b53b1c
https://research.vumc.nl/en/publications/7b3bd725-fd82-4214-85cb-1b6558b53b1c