Zobrazeno 1 - 6
of 6
pro vyhledávání: '"metabolism, Glutathione Transferase"'
Autor:
Maria Perez Carrion, Silvia Marsicano, F. Daniele, Antonella Marte, Francesca Pischedda, Eliana S. Di Cairano, Carla Perego, Ester Piovesana, Christian Johannes Gloeckner, Franco Onofri, Felix von Zweydorf, Giovanni Piccoli, Elisabeth Kremmer
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Sci. Rep. 7:5377 (2017)
Scientific reports 7(1), 5377 (2017). doi:10.1038/s41598-017-05760-9
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Sci. Rep. 7:5377 (2017)
Scientific reports 7(1), 5377 (2017). doi:10.1038/s41598-017-05760-9
Mutations in the Leucine-rich repeat kinase 2 gene (LRRK2) are associated with familial Parkinson’s disease (PD). LRRK2 protein contains several functional domains, including protein-protein interaction domains at its N- and C-termini. In this stud
Autor:
Meipei She, Carolyn J. Decker, Denise Muhlrad, Haiwei Song, Nan Chen, Dmitri I. Svergun, Roy Parker, Adam Round
Publikováno v:
Molecular cell 29, 337-349 (2008). doi:10.1016/j.molcel.2008.01.002
Summary A critical step in mRNA degradation is the removal of the 5′ cap structure, which is catalyzed by the Dcp1-Dcp2 complex. The crystal structure of an S . pombe Dcp1p-Dcp2n complex combined with small-angle X-ray scattering analysis (SAXS) re
Publikováno v:
FEBS Letters. 505:97-102
This study compared the relative levels of ryanodine receptor (RyR) isoforms, inositol 1,4,5-trisphosphate receptor (IP3R) isoforms, and calcineurin, plus their association with FKBP12 in brain, skeletal and cardiac tissue. FKBP12 demonstrated a very
Publikováno v:
European Journal of Biochemistry
European Journal of Biochemistry, Wiley, 2002, 269 (2), pp.494--501. ⟨10.1046/j.0014-2956.2001.02671.x⟩
European Journal of Biochemistry, Wiley, 2002, 269 (2), pp.494--501. ⟨10.1046/j.0014-2956.2001.02671.x⟩
Translocation through the plasma membrane is a major limiting step for the cellular delivery of macromolecules. A promising strategy to overcome this problem consists in the chemical conjugation (or fusion) to cell penetrating peptides (CPP) derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c8607936084bd6f0dc92037e1dbdf2f0
http://hdl.handle.net/11368/2552614
http://hdl.handle.net/11368/2552614
Autor:
Heidi Förster, Heike Beck, Peter J. Kuhlencordt, Pirkko Kölle, Marcus Conrad, Georg W. Bornkamm, Manuela Schneider, Pankaj Mandal
Publikováno v:
Cancer research 70(22), 9505-9514 (2010). doi:10.1158/0008-5472.CAN-10-1509
Tumor cells generate substantial amounts of reactive oxygen species (ROS), engendering the need to maintain high levels of antioxidants such as thioredoxin (Trx)- and glutathione (GSH)-dependent enzymes. Exacerbating oxidative stress by specifically