Zobrazeno 1 - 10
of 617
pro vyhledávání: '"metabolic dysregulation"'
Autor:
Arantza Lamas-Paz, Alejandro Hionides-Gutiérrez, Feifei Guo, Gonzalo Jorquera, Laura Morán-Blanco, Raquel Benedé-Ubieto, Mariana Mesquita, Olga Estévez-Vázquez, Kang Zheng, Marina Mazariegos, Elena Vázquez-Ogando, Elena Blázquez-López, Iris Asensio, Beste Mutlu, Beatriz Gomez-Santos, María Isabel Peligros, Javier Vaquero, Rafael Bañares, Teresa C. Delgado, María Luz Martínez-Chantar, Eduardo Martínez-Naves, Carlos Sanz-García, Mohamed Ramadan Mohamed, Sofía Tesolato, Pilar Iniesta, Rocío Gallego-Durán, Douglas Maya-Miles, Javier Ampuero, Manuel Romero-Gómez, Ana Martínez-Alcocer, David Sanfeliu-Redondo, Anabel Fernández-Iglesias, Jordi Gracia-Sancho, Mar Coll, Isabel Graupera, Pere Ginès, Andrea Ciudin, Jesús Rivera-Esteban, Juan M. Pericàs, Matías A. Ávila, Maria Dolores Frutos, Carlos Manuel Martínez-Cáceres, Bruno Ramos-Molina, Patricia Aspichueta, Pere Puigserver, Yulia A. Nevzorova, Francisco Javier Cubero
Publikováno v:
JHEP Reports, Vol 7, Iss 1, Pp 101230- (2025)
Background & Aims: Expression of P21, encoded by the CDKN1A gene, has been associated with fibrosis progression in steatotic liver disease (SLD); however, the underlying mechanisms remain unknown. In the present study, we investigated the function of
Externí odkaz:
https://doaj.org/article/4e2f28ede80d4cfa8f3201c467cc1073
Publikováno v:
Journal of Family Medicine and Primary Care, Vol 13, Iss 8, Pp 2857-2862 (2024)
Metabolic dysfunction associated fatty liver disease (MAFLD) was a concept suggested lately. Initially, the only criterion for the diagnosis of MAFLD was the absence of alcohol intake. With rising prevalence and studies assessing this condition, cert
Externí odkaz:
https://doaj.org/article/85bbe93867834eb8b07ae73692c2c851
Autor:
Seonkyeong Yang, Caitlin Knox
Publikováno v:
BMC Endocrine Disorders, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Lipodystrophy is characterized by progressive loss of adipose tissue and consequential metabolic abnormalities. With new treatments emerging for lipodystrophy, there is a growing need to understand the prevalence of specific comor
Externí odkaz:
https://doaj.org/article/d7b6fb6746934c92bc6d2d5af1f75ebd
Autor:
Shanshan Yu, Ming Chen, Xiaohua Zhu, Cheng Chen, Jinxiao Liang, Haiyong Wang, Jun Lu, Yongfeng Ding, Mei Kong, Lisong Teng, Donghui Zhou
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e34317- (2024)
Background: Gastric cancer (GC) is one of the most common malignant tumors in the world. It has become increasingly difficult to meet the needs of precision therapy using the existing molecular typing system. Therefore, developing a more effective mo
Externí odkaz:
https://doaj.org/article/5243a71184854d40be9a0b5a6e5b4fd1
Autor:
Yu, Shanshan a, 1, Chen, Ming b, 1, Zhu, Xiaohua c, 1, Chen, Cheng a, Liang, Jinxiao a, Wang, Haiyong a, Lu, Jun a, Ding, Yongfeng d, Kong, Mei e, Teng, Lisong a, Zhou, Donghui a, ⁎
Publikováno v:
In Heliyon 15 August 2024 10(15)
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundMetabolic dysregulation following sepsis can significantly compromise patient prognosis by altering immune-inflammatory responses. Despite its clinical relevance, the exact mechanisms of this perturbation are not yet fully understood.Method
Externí odkaz:
https://doaj.org/article/cad8eae75c8246babb2fa5ce5306edee
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cellular metabolism is a crucial determinant of immune cell fate and function. Extensive studies have demonstrated that metabolic decisions influence immune cell activation, differentiation, and cellular capacity, in the process impacting an organism
Externí odkaz:
https://doaj.org/article/ee5e45828f4d4c0faa1f2607c2d21c87
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e33093- (2024)
The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway is a critical innate immune pathway primarily due to its vital DNA sensing mechanism in pathogen defence. Recent research advances have shown that excessive activation
Externí odkaz:
https://doaj.org/article/d0709ababc6549109ae9b2323ae2529e
Autor:
Ling Wang, Juan Zhao, Madison Schank, Addison C. Hill, Puja Banik, Yi Zhang, Xiao Y. Wu, Janet W. Lightner, Shunbin Ning, Mohamed El Gazzar, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
Despite effective control of HIV replication by antiretroviral therapy (ART), a significant number of people living with HIV (PLWH) fail to achieve complete immune reconstitution and thus are deemed immune non-responders (INRs). Compared with immune
Externí odkaz:
https://doaj.org/article/ddb58edf242448ef8caf4bdb5f38788c
Autor:
Courage Dele Famusiwa, Sunday Solomon Josiah, Ibrahim Olabayode Saliu, Toluwase Hezekiah Fatoki, Haruna Isiyaku Umar, Afolabi Clement Akinmoladun
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 11, Iss , Pp 100439- (2024)
Introduction: Exposure to rotenone could directly affects the function of mitochondrial which leads to neurodegeneration. This study evaluated the therapeutic potential of taxifolin (Huāqí sōng dài; 花旗松甙) to alleviate metabolic and neuroc
Externí odkaz:
https://doaj.org/article/1fd6a9b886394cfab1c20ec75bcfe6e9