Zobrazeno 1 - 10
of 662
pro vyhledávání: '"metabolic dysfunction associated steatohepatitis"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Colorectal polyps are precursors of colorectal cancer. Metabolic dysfunction associated steatohepatitis (MASH) is one of metabolic dysfunction associated fatty liver disease (MAFLD) phenotypic manifestations. Much evidence has suggested an a
Externí odkaz:
https://doaj.org/article/c174f32656ac4bc5b7c1beb973db74b0
Autor:
Xiaoxiao Li, Kai Wang, Yunhong Sun, Yirong Wang, Jiaxuan Wu, Yanqi Dang, Meng Li, Wenjun Zhou
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Dietary cholesterol promotes metabolic dysfunction-associated steatohepatitis (MASH), with hepatic macrophages central to disease pathology. However, the mechanisms by which cholesterol-loaded macrophages influence MASH remain unc
Externí odkaz:
https://doaj.org/article/17dd03960ab9424199340898064289a0
Autor:
Yun Kyu Lee, Dong Hyeon Lee, Sae Kyung Joo, Heejoon Jang, Young Ho So, Siwon Jang, Dong Ho Lee, Jeong Hwan Park, Mee Soo Chang, Won Kim, Innovative Target Exploration of NAFLD (ITEN) Consortium
Publikováno v:
Gut and Liver, Vol 18, Iss 6, Pp 1048-1059 (2024)
Background/Aims: Combi-elastography is a B-mode ultrasound-based method in which two elastography modalities are utilized simultaneously to assess metabolic dysfunction-associated steatotic liver disease (MASLD). However, the performance of combi-ela
Externí odkaz:
https://doaj.org/article/3e145193d1314289af6146f04a04ed91
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Metabolic dysfunction-associated steatohepatitis (MASH) is a form of chronic liver inflammation associated with metabolic syndrome, such as obesity and a major cause of hepatocellular carcinoma (HCC). Multi-biotics, a soymilk fermented with
Externí odkaz:
https://doaj.org/article/83b07d903e25454c87f85ae0e42d6b27
Autor:
Rohit A. Sinha
Publikováno v:
Endocrinology and Metabolism, Vol 39, Iss 5, Pp 686-692 (2024)
The influence of thyroid hormone (TH) on liver metabolism has attracted the attention of pharmacologists seeking new treatments for metabolic dysfunction-associated steatotic liver disease (MASLD), an increasingly common metabolic disorder. In this c
Externí odkaz:
https://doaj.org/article/189733149b93498790ed8258536f9776
Autor:
Yang Song, Wei Zhong, Harry Cheuk-Hay Lau, Yating Zhang, Huayu Guan, Mingxu Xie, Suki Ha, Diwen Shou, Yongjian Zhou, Hongzhi Xu, Jun Yu, Xiang Zhang
Publikováno v:
Engineering, Vol 41, Iss , Pp 204-215 (2024)
Carboxyl ester lipase (CEL), a pivotal enzyme involved in lipid metabolism, is recurrently mutated in obese mice. Here, we aimed to elucidate the functional significance, molecular mechanism, and therapeutic potential of CEL in metabolic dysfunction-
Externí odkaz:
https://doaj.org/article/cee61af6a9e2452aa805d19c15d00b50
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Selecting the optimal non-invasive diagnostic model for MASLD (Metabolic Dysfunction-Associated Steatosis Liver Disease) and steatosis progression is a critical issue given the variety of available models. We aimed to compare the
Externí odkaz:
https://doaj.org/article/6da8b34768c74ebb8d827587589fd9ab
Autor:
Hsin-Tien Ho, Yu-Lueng Shih, Tien-Yu Huang, Wen-Hui Fang, Chang-Hsien Liu, Jung-Chun Lin, Chih-Weim Hsiang, Kai-Min Chu, Cheng-Huei Hsiong, Guan-Ju Chen, Yung-En Wu, Jia-Yu Hao, Chih-Wen Liang, Oliver Yoa-Pu Hu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Metabolic dysfunction-associated steatohepatitis (MASH) is a growing global health concern with no effective pharmacological treatments. SNP-630, a newly developed synthetic molecule with multiple mechanisms of action, and a mixtu
Externí odkaz:
https://doaj.org/article/ad7cb6c293e94ec0b686dbf6198ffa4d
Autor:
Tsutomu Wada, Yuki Takeda, Akira Okekawa, Go Komatsu, Yuichi Iwasa, Yasuhiro Onogi, Ichiro Takasaki, Takeru Hamashima, Masakiyo Sasahara, Hiroshi Tsuneki, Toshiyasu Sasaoka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The platelet-derived growth factor (PDGF) family contributes to the progression of steatohepatitis; however, changes in and the characteristics of isoform-specific expression remain unclear. Since diabetes is a major driver of metabolic dysf
Externí odkaz:
https://doaj.org/article/9ad6bd0aed7a48259c8e1cabd12831d3
Autor:
Ayana R. Kumar, Bhagyalakshmi Nair, Adithya Jayaprakash Kamath, Lekshmi R. Nath, Daniela Calina, Javad Sharifi-Rad
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-15 (2024)
Abstract Metabolic dysfunction-associated steatohepatitis (MASH) and progression to hepatocellular carcinoma (HCC) exhibits distinct molecular and immune characteristics. These traits are influenced by multiple factors, including the gut microbiome,
Externí odkaz:
https://doaj.org/article/9c8a6e1968304acb827c35e2b77b729e