Zobrazeno 1 - 10
of 116
pro vyhledávání: '"met mutation"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundThe distant metastasis of lung cancer primarily occurs in the bones, liver, brain, and lungs, while the breast is an extremely rare site of metastasis. There is very limited literature on the occurrence of breast metastasis from lung cancer
Externí odkaz:
https://doaj.org/article/03df023fe5fb465da80a070103544f73
Autor:
Yifan Du, Huimin Sun, Zhiyuan Shi, Xiuyuan Sui, Bin Liu, Zeyuan Zheng, Yankuo Liu, Zuodong Xuan, Min Zhong, Meiling Fu, Yang Bai, Qian Zhang, Chen Shao
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract The mutation of MET plays a crucial role in the initiation of cancer, while the Hedgehog (Hh) pathway also plays a significant role in cell differentiation and the maintenance of tumor stem cells. Conventional chemotherapy drugs are primaril
Externí odkaz:
https://doaj.org/article/99ac28747c40466fa538adaaddef39d1
Publikováno v:
Thoracic Cancer, Vol 13, Iss 11, Pp 1703-1711 (2022)
Abstract Background In patients with non‐small cell lung cancer (NSCLC) harboring driver alterations, the efficacy of immune checkpoint inhibitors (ICIs) remains uncertain. Our study aimed to examine the first‐line ICI efficacy in patients with N
Externí odkaz:
https://doaj.org/article/40e2e739b90842e2a06b9f4ce462d331
Autor:
Yan Chen, Bo Jiang, Yuange He, Chu Zhang, Wenjie Zhou, Cheng Fang, Dejian Gu, Minxia Zhang, Mei Ji, Juntao Shi, Xin Yang
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-7 (2022)
Abstract Background Targeted therapy has revolutionized the treatment of patients with malignancies harboring mutations in driver genes and has brought a favorable survival benefit to the population with actionable oncogenic mutations. In recent year
Externí odkaz:
https://doaj.org/article/6c8c3a9cb0384619829513aae5870a23
Autor:
Yongfeng Yu, Jianya Zhou, Xingya Li, Koichi Goto, Xuhong Min, Kazumi Nishino, Jiuwei Cui, Lin Wu, Jun Sakakibara, Yongqian Shu, Xiaorong Dong, Lu Li, Yasuto Yoneshima, Chengzhi Zhou, Xiaoling Li, Yiping Zhang, Dingzhi Huang, Aimin Zang, Wei Zhang, Xiuwen Wang, Li Zhang, Chong Bai, Jian Fang, Lejie Cao, Yanqiu Zhao, Yan Yu, Meiqi Shi, Diansheng Zhong, Fugen Li, Meng Li, Qiuxia Wu, Jun Zhou, Minghui Sun, Shun Lu
Publikováno v:
EClinicalMedicine, Vol 59, Iss , Pp 101952- (2023)
Summary: Background: Approximately 3–4% of patients with non-small-cell lung cancer (NSCLC) have MET exon 14 (METex14) skipping mutations. We report primary results from the phase 2 stage of a phase 1b/2 study of gumarontinib, a selective, potent,
Externí odkaz:
https://doaj.org/article/7812099965ee4424acef24e171e9a49c
Akademický článek
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Autor:
Klara Johansson, Adam Stenman, Johan O. Paulsson, Na Wang, Catharina Ihre-Lundgren, Jan Zedenius, C. Christofer Juhlin
Publikováno v:
Thyroid Research, Vol 14, Iss 1, Pp 1-10 (2021)
Abstract Background Thyroid cancer dedifferentiation is an unusual observation among young patients and is poorly understood, although a recent correlation to DICER1 gene mutations has been proposed. Case presentation A 28-year old patient presented
Externí odkaz:
https://doaj.org/article/cb4e0fb58ec84640bede08d65dfc596e
Autor:
M. O. Mandrina, V. V. Breder, M. V. Ivanov, A. A. Lebedeva, V. V. Gorbatsevich, K. K. Laktionov, P. V. Kononets
Publikováno v:
Медицинский совет, Vol 0, Iss 9, Pp 154-159 (2021)
Personalized therapy is starting to play an increasing role in modern approaches to the treatment of oncological diseases. The previously existing uniform standard for each malignant disease is expanded with new options and treatment possibilities, d
Externí odkaz:
https://doaj.org/article/57964881696b4a4fb74301f5336982f7
Akademický článek
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Publikováno v:
秋田医学. 49(3/4):131-138
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::6b235752db002b0c77fda88d5df81955
http://hdl.handle.net/10295/00006390
http://hdl.handle.net/10295/00006390