Zobrazeno 1 - 10
of 4 887
pro vyhledávání: '"mesolimbic"'
Autor:
Lennerz, Belinda S., author
Publikováno v:
Food & Addiction : A Comprehensive Handbook, 2024.
Externí odkaz:
https://doi.org/10.1093/oso/9780190671051.003.0036
Publikováno v:
Organoids, Vol 3, Iss 2, Pp 126-147 (2024)
The mesolimbic pathway connects ventral tegmental area dopaminergic neurons and striatal medium spiny neurons, playing a critical role in reward and stress behaviors. Exposure to substances of abuse during development and adulthood has been linked to
Externí odkaz:
https://doaj.org/article/099b494487654b8d83b08870e1cbd2f1
Autor:
Elizabeth Martin, Asadur Chowdury, John Kopchick, Patricia Thomas, Dalal Khatib, Usha Rajan, Caroline Zajac-Benitez, Luay Haddad, Alireza Amirsadri, Alfred J. Robison, Katherine N. Thakkar, Jeffrey A. Stanley, Vaibhav A. Diwadkar
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionSchizophrenia is characterized by a loss of network features between cognition and reward sub-circuits (notably involving the mesolimbic system), and this loss may explain deficits in learning and cognition. Learning in schizophrenia has
Externí odkaz:
https://doaj.org/article/6af58a1492f443ef80462fc8f425b07c
Autor:
Jennifer I. Mejaes, Jacqueline Saenz, Chris O’Brien, Carina M. Pizzano, Ping-Yue Pan, David J. Barker
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
The synaptojanin-1 (SYNJ1) gene is known to be important for dopamine-related disorders. Recent evidence has demonstrated that Synj1 deficient mice (Synj1+/−) have impairments in dopaminergic synaptic vesicular recycling. However, less is known abo
Externí odkaz:
https://doaj.org/article/ca2696e408a74e8686d9fde09b2a9ae8
Publikováno v:
Frontiers in Neuroanatomy, Vol 18 (2024)
Gestational exposure to valproic acid (VPA) is a valid rodent model of human autism spectrum disorder (ASD). VPA treatment is known to bring about specific behavioral deficits of sociability, matching similar alterations in human autism. Previous qua
Externí odkaz:
https://doaj.org/article/5441ba83c243421d93fdb7a8d2df8345
Autor:
Ming Li
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Maternal behavior research in laboratory rats has revealed important behavioral and neurobiological mechanisms governing the onset, maintenance and decline of maternal behavior. However, the extent to which these mechanisms are evolutionarily conserv
Externí odkaz:
https://doaj.org/article/78dce6cb41b143208e60013e68d69d9e
Akademický článek
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Autor:
Kenneth Blum, Abdalla Bowirrat, Keerthy Sunder, Panayotis K. Thanos, Colin Hanna, Mark S. Gold, Catherine A. Dennen, Igor Elman, Kevin T. Murphy, Milan T. Makale
Publikováno v:
Brain Sciences, Vol 14, Iss 7, p 733 (2024)
Autism spectrum disorder (ASD) is primarily characterized by core deficits in social skills, communication, and cognition and by repetitive stereotyped behaviors. These manifestations are variable between individuals, and ASD pathogenesis is complex,
Externí odkaz:
https://doaj.org/article/1d2e6b6595fd4ea9a192e552e154de64
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/aea0b592dfec433ebb5e1ccde6e154b3
Autor:
Emily M. Black, Shanna B. Samels, Wei Xu, Jessica R. Barson, Caroline E. Bass, Sandhya Kortagere, Rodrigo A. España
Publikováno v:
Addiction Neuroscience, Vol 7, Iss , Pp 100104- (2023)
The hypocretins/orexins (HCRT) have been demonstrated to influence motivation for cocaine through actions on dopamine (DA) transmission. Pharmacological or genetic disruption of the hypocretin receptor 1 (Hcrtr1) reduces cocaine self-administration,
Externí odkaz:
https://doaj.org/article/747eda9d96d94f2d9147c6f9f39294d2