Acquisition of flucytosine, azole, and caspofungin resistance in Candida glabrata bloodstream isolates serially obtained from a hematopoietic stem cell transplant recipient

Autor: Nicolas Papon, Patricia Ribaud, Thierry Noël, Claire Lacroix, Gérard Socié, Aurélie Girard, Florence Chapeland-Leclerc, Christophe Hennequin

Publikováno v: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2010, 54 (3), pp.1360-2. ⟨10.1128/AAC.01138-09⟩

We describe the acquisition of flucytosine, azole, and caspofungin resistance in sequential Candida glabrata bloodstream isolates collected from a bone marrow transplant patient with clinical failure. Point mutations in C. glabrata FUR1 ( CgFUR1 ) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b919aa97c8f1a19edd4c887e229bab
https://hal.archives-ouvertes.fr/hal-00594730

Molecular mechanism of flucytosine resistance in Candida lusitaniae: contribution of the FCY2, FCY1, and FUR1 genes to 5-fluorouracil and fluconazole cross-resistance

Autor: Papon, Nicolas, Noël, Thierry, Florent, Martine, Gibot-Leclerc, Stéphanie, Jean, Dorothée, Chastin, Christiane, Villard, Jean, Chapeland-Leclerc, Florence

Publikováno v: Antimicrobial Agents and Chemotherapy, Vol. 51, No 1 (2007) pp. 369-371
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2007, 51 (1), pp.369-71. ⟨10.1128/AAC.00824-06⟩

International audience; Inactivation of the FCY2 (cytosine permease), FCY1 (cytosine deaminase), and FUR1 (uracil phosphoribosyltransferase) genes in Candida lusitaniae produced two patterns of resistance to flucytosine. Mutant fur1 demonstrated resi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2ba24ff0f0ba7af192ab872ec7082246
https://archive-ouverte.unige.ch/unige:149128

[Comparative study of two systems for the determination of the sensitivity of yeasts to antifungal agents]

Autor: de Montclos, M, de Montclos, H., Flandrois, Jean-Pierre

Publikováno v: Pathologie Biologie
Pathologie Biologie, Elsevier Masson, 1992, 40 (5), pp.495-9
Pathologie Biologie, 1992, 40 (5), pp.495-9

International audience; One hundred yeast strains (including 60 Candida albicans) were tested in two laboratories using two different antifungal susceptibility test kits, ATB Fungus and Mycostandard. Tests were carried out under everyday work conditi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::106d78e441deb03cbedaef85b75a8703
https://hal.archives-ouvertes.fr/hal-02332641