Výsledky vyhledávání - "mesangial expansion"

Akademický článek

Exposure to High-Fat Style Diet Induced Renal and Liver Structural Changes, Lipid Accumulation and Inflammation in Intact and Ovariectomized Female Rats

Autor: Sucedaram Y, Johns EJ, Husain R, Abdul Sattar M, H Abdulla M, Nelli G, Rahim NS, Khalilpourfarshbafi M, Abdullah NA

Publikováno v: Journal of Inflammation Research, Vol Volume 14, Pp 689-710 (2021)

Yamuna Sucedaram,1 Edward James Johns,2 Ruby Husain,3 Munavvar Abdul Sattar4 ,† Mohammed H Abdulla,2 Giribabu Nelli,3 Nur Syahrina Rahim,5 Manizheh Khalilpourfarshbafi,1 Nor Azizan Abdullah1 1Department of Pharmacology, Faculty of Medicine, Univers

Externí odkaz: https://doaj.org/article/17da691d7b3e4988ae8e91b186b58141

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Akademický článek

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Metformin Is Associated with the Inhibition of Renal Artery AT1R/ET-1/iNOS Axis in a Rat Model of Diabetic Nephropathy with Suppression of Inflammation and Oxidative Stress and Kidney Injury

Autor: Amal F. Dawood, Amro Maarouf, Norah M. Alzamil, Maha A. Momenah, Ayed A. Shati, Nervana M. Bayoumy, Samaa S. Kamar, Mohamed A. Haidara, Asmaa M. ShamsEldeen, Hanaa Z. Yassin, Peter W. Hewett, Bahjat Al-Ani

Publikováno v: Biomedicines, Vol 10, Iss 7, p 1644 (2022)

Diabetes is the most common cause of end-stage renal disease, also called kidney failure. The link between the renal artery receptor angiotensin II type I (AT1R) and endothelin-1 (ET-1), involved in vasoconstriction, oxidative stress, inflammation an

Externí odkaz: https://doaj.org/article/600eb28520a941abbebb24d26f02891a

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Akademický článek

Impact of sex on diabetic nephropathy and the renal transcriptome in UNx db/db C57BLKS mice

Autor: Frederikke E. Sembach, Lisbeth N. Fink, Thea Johansen, Brandon B. Boland, Thomas Secher, Sebastian T. Thrane, Jens C. Nielsen, Keld Fosgerau, Niels Vrang, Jacob Jelsing, Tanja X. Pedersen, Mette V. Østergaard

Publikováno v: Physiological Reports, Vol 7, Iss 24, Pp n/a-n/a (2019)

Abstract Diabetic nephropathy (DN) is associated with albuminuria and loss of kidney function and is the leading cause of end‐stage renal disease. Despite evidence of sex‐associated differences in the progression of DN in human patients, male mic

Externí odkaz: https://doaj.org/article/ffaf8874a3d04edbbc1a60ff317b4f54

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Akademický článek

A Stereological Study Concerning the Role of Satureja Khuzestanica Essential Oil in the Improvement of Mesangial Expansion in Uninephrectomized Diabetic Rats

Autor: Ahmad Tamjidipour, Majid Tavafi, Hassan Ahmadvand

Publikováno v: Herbal Medicines Journal, Vol 0, Iss 0, Pp 139-145 (2018)

Background and Aim: Mesangial expansion may lead to renal failure due to the stenosis or occlusion of glomerular capillary lumen in diabetic patients. Oxidative stress is the main cause of diabetic mesangial expansion. The information obtained from t

Externí odkaz: https://doaj.org/article/132ca1b0638b4df2ba03d55329a008f6

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Akademický článek

Inhibition of Akt/mTOR/p70S6K Signaling Activity With Huangkui Capsule Alleviates the Early Glomerular Pathological Changes in Diabetic Nephropathy

Autor: Wei Wu, Wei Hu, Wen-Bei Han, Ying-Lu Liu, Yue Tu, Hai-Ming Yang, Qi-Jun Fang, Mo-Yi Zhou, Zi-Yue Wan, Ren-Mao Tang, Hai-Tao Tang, Yi-Gang Wan

Publikováno v: Frontiers in Pharmacology, Vol 9 (2018)

Huangkui capsule (HKC), a Chinese modern patent medicine extracted from Abelmoschus manihot (L.) medic, has been widely applied to clinical therapy in the early diabetic nephropathy (DN) patients. However, it remains elusive whether HKC can ameliorat

Externí odkaz: https://doaj.org/article/777a94d790be46f5a60dcf650dcff205

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Exposure to High-Fat Style Diet Induced Renal and Liver Structural Changes, Lipid Accumulation and Inflammation in Intact and Ovariectomized Female Rats

Autor: Nor Azizan Abdullah, Edward J. Johns, Giribabu Nelli, Manizheh Khalilpourfarshbafi, Munavvar A. Sattar, Nur Syahrina Rahim, Yamuna Sucedaram, Mohammed H. Abdulla, Ruby Husain

Publikováno v: Journal of Inflammation Research

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5a3df2f0d9b4339dd47471efdb257f
https://doi.org/10.2147/jir.s299083

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Inhibition of notch signalling and mesangial expansion by combined glucagon like peptide-1 agonist and crocin therapy in animal model of diabetic nephropathy

Autor: Maged Ahmed Haroun, Eman Mumtaz El-Gamal, Shaimaa Nasr Amin, Samaa S Kamar, Laila A. Rashed

Publikováno v: Archives of Physiology and Biochemistry. 129:544-554

Diabetic nephropathy (DN) is one of the devastating complications in diabetes mellitus (DM). Glucagon-like peptide-1 (GLP-1) is one of the incretins secreted from L cells in the intestine. Crocin (a carotenoid component of saffron) has antioxidants p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8680531b848fcc8b6b66c97cfd6052bc
https://doi.org/10.1080/13813455.2020.1846203

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