Absorption Kinetics of Subcutaneously Administered Ceftazidime in Hypoperfused Guinea Pigs

Autor: Tsuyoshi Ebihara, MS, Shinji Oshima, PhD, Mitsuyoshi Okita, MS, Sayumi Shiina, MS, Akio Negishi, BS, Kousuke Ohara, BS, Shigeru Ohshima, PhD, Hiroyuki Iwasaki, MD, Akira Yoneyama, MD, Eiji Kitazumi, MD, Daisuke Kobayashi, PhD

Publikováno v: Current Therapeutic Research, Vol 77, Iss C, Pp 7-13 (2015)

Background: Pneumonia is the most common cause of death in patients with severe motor and intellectual disabilities (SMID), and intravenous ceftazidime (CAZ) is a widely used treatment for such infections. However, intravenous administration in patie

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Absorption Kinetics of Subcutaneously Administered Ceftazidime in Hypoperfused Guinea Pigs.

Autor: Ebihara T; Department of Pharmacy Services, National Rehabilitation Center for Children with Disabilities, Tokyo, Japan., Oshima S; Department of Analytical Pharmaceutics and Informatics, Faculty of Pharmaceutical Sciences, Josai University, Saitama, Japan., Okita M; Department of Analytical Pharmaceutics and Informatics, Faculty of Pharmaceutical Sciences, Josai University, Saitama, Japan., Shiina S; Department of Analytical Pharmaceutics and Informatics, Faculty of Pharmaceutical Sciences, Josai University, Saitama, Japan., Negishi A; Department of Analytical Pharmaceutics and Informatics, Faculty of Pharmaceutical Sciences, Josai University, Saitama, Japan., Ohara K; Department of Analytical Pharmaceutics and Informatics, Faculty of Pharmaceutical Sciences, Josai University, Saitama, Japan., Ohshima S; Department of Analytical Pharmaceutics and Informatics, Faculty of Pharmaceutical Sciences, Josai University, Saitama, Japan., Iwasaki H; Department of Pediatrics, National Rehabilitation Center for Children with Disabilities, Tokyo, Japan., Yoneyama A; Department of Pediatrics, National Rehabilitation Center for Children with Disabilities, Tokyo, Japan., Kitazumi E; Department of Pediatrics, National Rehabilitation Center for Children with Disabilities, Tokyo, Japan., Kobayashi D; Department of Analytical Pharmaceutics and Informatics, Faculty of Pharmaceutical Sciences, Josai University, Saitama, Japan.

Publikováno v: Current therapeutic research, clinical and experimental [Curr Ther Res Clin Exp] 2014 Nov 18; Vol. 77, pp. 7-13. Date of Electronic Publication: 2014 Nov 18 (Print Publication: 2015).