Zobrazeno 1 - 10
of 1 614 240
pro vyhledávání: '"meng"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a malignant neoplasm with detrimental implications for human health. The landscape of ESCC therapy has been revolutionized by the introduction of immunotherapy, specifically involving i
Externí odkaz:
https://doaj.org/article/cbff68607cde4c7eb4022dd69fc6cb51
Autor:
Meng Guan, Kai Cheng, Xiao-Ting Xie, Yong Li, Meng-Wen Ma, Bin Zhang, Si Chen, Wei Chen, Bo Liu, Jin-Xuan Fan, Yuan-Di Zhao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Cuproptosis is an emerging mode of programmed cell death for tumor suppression but sometimes gets resisted by tumor cells resist under specific mechanisms. Inhibiting copper transporter ATPase (ATP7A) was found to disrupt copper ion homeosta
Externí odkaz:
https://doaj.org/article/1f201d2373334c37a30cd8c111d38a58
Autor:
Ben Li, Jian Ma, Honghai Chen, Meng Guo, Jiyuan Li, Meng Ren, Hongxian Yan, Yongming Xiao, Marcella Festa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Prehistoric settlement patterns on the Tibetan Plateau, particularly in the Qaidam Basin, have drawn significant scholarly interest. Yet, limited data have hindered a comprehensive understanding the Bronze Age chronology and landscape exploi
Externí odkaz:
https://doaj.org/article/65236c5aa6994795a34a4c82cab9aa19
Autor:
Qingya Liu, Yun Yang, Meng Pan, Kun Shi, Dong Mo, Yicong Li, Meng Wang, Linfeng Guo, Zhiyong Qian
Publikováno v:
Bioactive Materials, Vol 41, Iss , Pp 413-426 (2024)
Camptothecin (CPT) exhibits potent antitumor activity; however, its clinical application is limited by significant gastrointestinal adverse effects (GAEs). Although the severity of GAEs associated with CPT derivatives has decreased, the incidence rat
Externí odkaz:
https://doaj.org/article/781146cb3c244788a055150516694bb6
Autor:
Xia Zhou, Wen‐Wen Yin, Chao‐Juan Huang, Si‐Lu Sun, Zhi‐Wei Li, Ming‐Xu Li, Meng‐Meng Ren, Ya‐Ting Tang, Jia‐Bin Yin, Wen‐Hui Zheng, Chao Zhang, Yu Song, Ke Wan, Yue Sun, Xiao‐Qun Zhu, Zhong‐Wu Sun
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 6, Pp 2717-2728 (2024)
ABSTRACT Background Both Alzheimer's disease (AD) and cerebral small vessel disease (CSVD) manifest in cognitive impairment and gait disorders. The precise similarities and differences in gait characteristics and underlying neuroimaging mechanisms re
Externí odkaz:
https://doaj.org/article/5c5940597ee2448e8be19246d64e1155
Autor:
Yanghao Meng, Yi Yang, Hualei Sun, Sasa Zhang, Jianlin Luo, Liucheng Chen, Xiaoli Ma, Meng Wang, Fang Hong, Xinbo Wang, Xiaohui Yu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract Density wave (DW) order is believed to be correlated with superconductivity in the recently discovered high-temperature superconductor La3Ni2O7. However, experimental investigations of its evolution under high pressure are still lacking. Her
Externí odkaz:
https://doaj.org/article/644d224f3af041448c847c46cf09b1e9
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Preeclampsia (PE) is a multifaceted pregnancy syndrome marked by multiple system involvement and a significant contributor to maternal mortality. This condition is characterized by a critical lack of early diagnostic measures and
Externí odkaz:
https://doaj.org/article/b155c72102ef4d7aa4363f253501ba96
Publikováno v:
MycoKeys, Vol 110, Iss , Pp 255-272 (2024)
Absidia is distributed worldwide and primarily isolated from soil, feces, and decaying plants. The genus was initially classified into Absidiaceae and then Mucoraceae, and currently belongs to Cunninghamellaceae and is further divided into Absidia s.
Externí odkaz:
https://doaj.org/article/c75ae7ce6d1544a8a173434cd64b8ace
Autor:
Li-li Ren, Yan-ru Song, Zhen-chuan Song, Hua Yang, Qian Zhang, Meng-meng Ji, Na Xiao, Ming Wen, Ji-hai Wang
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract HER2 antagonists remain the cornerstone of therapy for patients with HER2-positive breast cancer. This study introduces a novel small-molecule inhibitor of DNA methyltransferase 1 (DNMT-1), referred to as DI-1, designed to synergize with HER
Externí odkaz:
https://doaj.org/article/22dbd43e0e18491486209a6e2b11e13c
Autor:
Nancy O. Nou, Jonathan K. Covington, Dengxun Lai, Xavier Mayali, Cale O. Seymour, Juliet Johnston, Jian-Yu Jiao, Steffen Buessecker, Damon Mosier, Alise R. Muok, Nicole Torosian, Allison M. Cook, Ariane Briegel, Tanja Woyke, Emiley Eloe-Fadrosh, Nicole Shapiro, Scott G. Bryan, Savannah Sleezer, Joshua Dimapilis, Cristina Gonzalez, Lizett Gonzalez, Marlene Noriega, Matthias Hess, Ross P. Carlson, Lan Liu, Meng-Meng Li, Zheng-Han Lian, Siqi Zhu, Fan Liu, Xian Sun, Beile Gao, Ritesh Mewalal, Miranda Harmon-Smith, Ian K. Blaby, Jan-Fang Cheng, Peter K. Weber, Gabriela Grigorean, Wen-Jun Li, Anne E. Dekas, Jennifer Pett-Ridge, Jeremy A. Dodsworth, Marike Palmer, Brian P. Hedlund
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Few aerobic hyperthermophilic microorganisms degrade polysaccharides. Here, we describe the genome-enabled enrichment and optical tweezer-based isolation of an aerobic polysaccharide-degrading hyperthermophile, Fervidibacter sacchari, previo
Externí odkaz:
https://doaj.org/article/8984212f4fcd4e72994805a67963bf76