Zobrazeno 1 - 10
of 95
pro vyhledávání: '"memory-like NK cells"'
Autor:
Mohammad Arif Rahman, Isabela Silva de Castro, Luca Schifanella, Massimiliano Bissa, Genoveffa Franchini
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
SIV and HIV-based envelope V1-deleted (ΔV1) vaccines, delivered systemically by the DNA/ALVAC/gp120 platform, decrease the risk of mucosal SIV or SHIV acquisition more effectively than V1-replete vaccines. Here we investigated the induction of mucos
Externí odkaz:
https://doaj.org/article/5e6a82b3d6df4b6a8438171f1e32dd9d
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-17 (2024)
Abstract Background Natural killer (NK) cells are effective in attacking tumor cells that escape T cell attack. Memory NK cells are believed to function as potent effector cells in cancer immunotherapy. However, knowledge of their induction, identifi
Externí odkaz:
https://doaj.org/article/331d444c55384d6291ec87e1d160ecf3
Autor:
Jeremiah L. Oyer, Tayler J. Croom-Perez, Md Faqrul Hasan, Javier A. Rivera-Huertas, Sarah B. Gitto, Joanna M. Mucha, Xiang Zhu, Deborah A. Altomare, Robert Y. Igarashi, Alicja J. Copik
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
NK cell therapeutics have gained significant attention as a potential cancer treatment. Towards therapeutic use, NK cells need to be activated and expanded to attain high potency and large quantities for an effective dosage. This is typically done by
Externí odkaz:
https://doaj.org/article/a1322c48c6044a24a3fa333918436d9b
Publikováno v:
Infection and Drug Resistance, Vol Volume 16, Pp 2349-2364 (2023)
Chen Liang,1,2,* Shanshan Li,1,* Jinfeng Yuan,1 Yanhua Song,3 Weicong Ren,1 Wei Wang,1 Yuanyuan Shang,1 Shenjie Tang,2 Yu Pang1 1Department of Bacteriology and Immunology, Beijing Key Laboratory on Drug-Resistant Tuberculosis Research, Beijin
Externí odkaz:
https://doaj.org/article/53b9d017e83941ac9e24dae8532448c2
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Cytokine-induced memory-like natural killer (CIML NK) cells have been found to possess potent antitumor responses and induce complete remissions in patients with leukemia. However, the poor infiltration of transferred NK cells is
Externí odkaz:
https://doaj.org/article/e919109ecb344c80adcd7b3e5582beeb
Autor:
Sofía Carreira-Santos, Nelson López-Sejas, Marina González-Sánchez, Eva Sánchez-Hernández, Alejandra Pera, Fakhri Hassouneh, Esther Durán, Rafael Solana, Javier G. Casado, Raquel Tarazona
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionNatural killer (NK) cells are a key component of the innate immune system, involved in defending the host against virus-infected cells and tumor immunosurveillance. Under in vitro culture conditions, IL-12/15/18 can induce a memory-like p
Externí odkaz:
https://doaj.org/article/52eb3c2b2c4c4119bfdeb8dd97eb00b3
Akademický článek
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Autor:
Bailin He, Qiusui Mai, Yunyi Pang, Shikai Deng, Yi He, Rongtao Xue, Na Xu, Hongsheng Zhou, Xiaoli Liu, Li Xuan, Chengyao Li, Qifa Liu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
CD19 chimeric antigen receptor (CAR) engineered NK cells have been used for treating patients with relapsed and/or refractory B cell malignancies and show encouraging outcomes and safety profile. However, the poor persistence of NK cells remains a ma
Externí odkaz:
https://doaj.org/article/60a17ec8aa1f441fb196ebb961f329a0
Autor:
Mubin Tarannum, Rizwan Romee
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-10 (2021)
Abstract Natural killer cells are an important part of the innate immune system mediating robust responses to virus-infected and malignant cells without needing prior antigen priming. NK cells have always been thought to be short-lived and with no an
Externí odkaz:
https://doaj.org/article/71996d026732453292130b7c623ad196
Autor:
Dandan Wang, Subramaniam Malarkannan
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-3 (2022)
Abstract A recent study highlights the presence of a unique memory-like natural killer (NK) cell subset, which accumulates with aging and appears to associate withdisease severity in COVID-19 patients. While the clinical relevance of memory in NK cel
Externí odkaz:
https://doaj.org/article/5ab2b7de021c4763b711ba1fc8a26c32