Zobrazeno 1 - 10
of 337
pro vyhledávání: '"memory-like"'
Autor:
Aydin Eresen, Zigeng Zhang, Guangbo Yu, Qiaoming Hou, Zhilin Chen, Zeyang Yu, Vahid Yaghmai, Zhuoli Zhang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Heterogeneity of hepatocellular carcinoma (HCC) presents significant challenges for therapeutic strategies and necessitates combinatorial treatment approaches to counteract suppressive behavior of tumor microenvironment and achiev
Externí odkaz:
https://doaj.org/article/950fad8b8af9492ba6da0a8ed1a941cb
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e39736- (2024)
As nonhuman primates are immunologically the closest model to humans, a comprehensive understanding of T-cell development in these species is crucial. However, the differentiation pathways in which thymocytes participate, along with their heterogenei
Externí odkaz:
https://doaj.org/article/5dba43daccee4688b4461bcbdbf05fc4
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Small extracellular vesicles (sEV) derived from diverse natural killer (NK) cell lines have proven their exceptional antitumor activities. However, sEV from human primary NK cells, especially memory-like NK cells, are rarely utilized for can
Externí odkaz:
https://doaj.org/article/d05fb92faadc45f9bf72d9bbb159057c
Autor:
Mohammad Arif Rahman, Isabela Silva de Castro, Luca Schifanella, Massimiliano Bissa, Genoveffa Franchini
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
SIV and HIV-based envelope V1-deleted (ΔV1) vaccines, delivered systemically by the DNA/ALVAC/gp120 platform, decrease the risk of mucosal SIV or SHIV acquisition more effectively than V1-replete vaccines. Here we investigated the induction of mucos
Externí odkaz:
https://doaj.org/article/5e6a82b3d6df4b6a8438171f1e32dd9d
Publikováno v:
In Heliyon 15 November 2024 10(21)
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-17 (2024)
Abstract Background Natural killer (NK) cells are effective in attacking tumor cells that escape T cell attack. Memory NK cells are believed to function as potent effector cells in cancer immunotherapy. However, knowledge of their induction, identifi
Externí odkaz:
https://doaj.org/article/331d444c55384d6291ec87e1d160ecf3
Publikováno v:
Viruses, Vol 16, Iss 11, p 1746 (2024)
Natural killer (NK) cells are innate lymphocytes that can rapidly mount a response to their targets by employing diverse mechanisms. Due to their functional attributes, NK cells have been implicated in anti-viral and anti-tumour immune responses. Alt
Externí odkaz:
https://doaj.org/article/3c67c0214a664049b2661dcf9dae4d78
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32622- (2024)
Natural Killer (NK) cells are conventionally thought to be an indefinite part of innate immunity. However, in a specific subset of NK cells, recent data signify an extension of their “duties” in immune surveillance and response, having characteri
Externí odkaz:
https://doaj.org/article/221b0fa51d184f10964b051cddbefc91
Autor:
Zeliang Yang, Liang Liu, Zhenyu Zhu, Zixi Hu, Bowen Liu, Jingjing Gong, Yuan Jin, Juan Luo, Yichen Deng, Yan Jin, Guangxi Wang, Yuxin Yin
Publikováno v:
Advanced Science, Vol 11, Iss 16, Pp n/a-n/a (2024)
Abstract CD8+ T cells are critical for host antitumor responses, whereas persistent antigenic stimulation and excessive inflammatory signals lead to T cell dysfunction or exhaustion. Increasing early memory T cells can improve T cell persistence and
Externí odkaz:
https://doaj.org/article/97b7a28ed90543c28c4c438489b0725a
Autor:
Jeremiah L. Oyer, Tayler J. Croom-Perez, Md Faqrul Hasan, Javier A. Rivera-Huertas, Sarah B. Gitto, Joanna M. Mucha, Xiang Zhu, Deborah A. Altomare, Robert Y. Igarashi, Alicja J. Copik
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
NK cell therapeutics have gained significant attention as a potential cancer treatment. Towards therapeutic use, NK cells need to be activated and expanded to attain high potency and large quantities for an effective dosage. This is typically done by
Externí odkaz:
https://doaj.org/article/a1322c48c6044a24a3fa333918436d9b