Zobrazeno 1 - 10
of 5 178
pro vyhledávání: '"membrane-bound"'
Autor:
Chaoting Zhang, Ting Liu, Shance Li, Xia Teng, Yuge Zhu, Guanyu Zhang, Huimin Xie, Kang Sun, Jiaxin Tu, Wenjun Yang, Zheming Lu
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-6 (2024)
Abstract Enhancing the efficacy of CD19 CAR-T cell therapy can significantly improve patient outcomes by reducing relapse rates in CD19 + B cell malignancies. Exogenous or transgenic cytokines are often used to boost the expansion and durability of C
Externí odkaz:
https://doaj.org/article/83f839168cd84edbb25365849d15419f
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Protein shuttling between the cytoplasm and nucleus is a unique phenomenon in eukaryotic organisms, integral to various cellular functions. Membrane-bound transcription factors (MTFs), a specialized class of nucleocytoplasmic shuttling prote
Externí odkaz:
https://doaj.org/article/cbc7b9faeac84515870f0a6370aeacd6
Autor:
Zhen Sun, Aotian Xu, Zhaojun Wu, Xiaohao Lan, Ganchen Gao, Bin Guo, Zhongjie Yu, Lin Shao, Hao Wu, Min Lv, Yongjie Wang, Yi Zhao, Bin Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe adoptive cell transfer of tumor-infiltrating lymphocytes (TILs) has proven clinically beneficial in patients with non-small cell lung cancer refractory to checkpoint blockade immunotherapy, which has prompted interest in TIL-adoptive
Externí odkaz:
https://doaj.org/article/5ee7e9e434954d7b9466a131db220ef4
Autor:
Takashi Watanabe, Hikaru Hata, Yoshiki Mochizuki, Fumie Yokoyama, Tomoko Hasegawa, Naveen Kumar, Tomohiro Kurosaki, Osamu Ohara, Hidehiro Fukuyama
Publikováno v:
eLife, Vol 13 (2024)
Antibodies are powerful tools for the therapy and diagnosis of various diseases. In addition to conventional hybridoma-based screening, recombinant antibody-based screening has become a common choice; however, its application is hampered by two facto
Externí odkaz:
https://doaj.org/article/7c8635ab87ed41a1accabbc80ff78a36
Autor:
Chuan Li, Yun Bai, Yuwei Hou, Siyu Wang, Yue Xin, Tao Yu, Jing Wang, Xiaowei Liu, Hongyang Yi, Chao Xia, Hai Lan, Moju Cao
Publikováno v:
Crop Journal, Vol 12, Iss 3, Pp 676-687 (2024)
Maize plant architecture influences planting density and, in turn, grain yield. Most of the plant architecture-related traits can be described as organ size. We describe a miniature maize mutant, Tiny plant 4 (Tip4), which exhibits reduced size of mu
Externí odkaz:
https://doaj.org/article/a8ab712ec8b04aceba491cb718d156e5
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 05, Pp 06-11 (2024)
Introduction: Colorectal Carcinoma (CRC) is one of the significant causes of fatality worldwide. High-grade and high-stage cancers contribute to this fatality. In most terminal cases, new immunomarkers (CD55 and CD59) are commonly detected as positiv
Externí odkaz:
https://doaj.org/article/4f215cc1c0bd4ba890a64905daa72504
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 808-820 (2024)
Folic acid is a fully oxidized synthetic folate with high bioavailability and stability which has been extensively prescribed to prevent congenital disabilities. Here we revealed the immunosuppressive effect of folic acid by targeting splenic margina
Externí odkaz:
https://doaj.org/article/8cd3e9c02bba415792ddb10d5445ad44
Autor:
Rodolfo García-Contreras, Javier de la Mora, Héctor Manuel Mora-Montes, José A. Martínez-Álvarez, Marcos Vicente-Gómez, Felipe Padilla-Vaca, Naurú Idalia Vargas-Maya, Bernardo Franco
Publikováno v:
PeerJ, Vol 12, p e17496 (2024)
Pyrophosphatases (PPases) are enzymes that catalyze the hydrolysis of pyrophosphate (PPi), a byproduct of the synthesis and degradation of diverse biomolecules. The accumulation of PPi in the cell can result in cell death. Although the substrate is t
Externí odkaz:
https://doaj.org/article/eee2b51eeb2a436694d34070420e6548
Autor:
Rosa Fernández, Karla Ramírez, Roberto Lorente-Bermúdez, Esther Gómez-Gil, Mireia Mora, Antonio Guillamon, Eduardo Pásaro
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionGender incongruence (GI) is characterized by a marked incongruence between an individual’s experienced/expressed gender and the assigned sex at birth. It includes strong displeasure about his or her sexual anatomy and secondary sex char
Externí odkaz:
https://doaj.org/article/846245694a8844f39a9d1fd164972431
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 55, Pp 1064-1074 (2023)
Membraneless organelles (MLO) regulate diverse biological processes in a spatiotemporally controlled manner spanning from inside to outside of the cells. The plasma membrane (PM) at the cell surface serves as a central platform for forming multi-comp
Externí odkaz:
https://doaj.org/article/423a1133b3084852bc2a58012c1157b2