Zobrazeno 1 - 10
of 886
pro vyhledávání: '"membrane ruffling"'
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-14 (2021)
Abstract Alzheimer’s disease (AD) is known by characteristic features, extracellular burden of amyloid-β and intracellular neuronal Tau. Microglia, the innate immune cell of the brain has the ability to clear the burden of accumulated proteins via
Externí odkaz:
https://doaj.org/article/200320c1adc644d7a8ec5eb18482183b
Autor:
Heon-Su Kim, Jung-Soo Suh, Yoon-Kwan Jang, Sang-Hyun Ahn, Gyu-Ho Choi, Jin-Young Yang, Gah-Hyun Lim, Youngmi Jung, Jie Jiang, Jie Sun, Myungeun Suk, Yingxiao Wang, Tae-Jin Kim
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
A mechanosensitive ion channel, Piezo1 induces non-selective cation flux in response to various mechanical stresses. However, the biological interpretation and underlying mechanisms of cells resulting from Piezo1 activation remain elusive. This study
Externí odkaz:
https://doaj.org/article/e361e3bd8f02445a8f8794dbd6da8626
Publikováno v:
Animal Cells and Systems, Vol 22, Iss 2, Pp 69-75 (2018)
p130 Crk-associated substrate (Cas) is an adaptor protein associating with many other signaling proteins and regulates a various biological processes including cell adhesion, migration, and growth factor stimulation. However, the exact functional rol
Externí odkaz:
https://doaj.org/article/ad4c6520416f4810b4eb3caa0fefa1de
Autor:
Castoria, Gabriella, Lombardi, Maria, Barone, Maria Vittoria, Bilancio, Antonio, Di Domenico, Marina, Bottero, Daniela, Vitale, Flavia, Migliaccio, Antimo, Auricchio, Ferdinando
Publikováno v:
The Journal of Cell Biology, 2003 May 01. 161(3), 547-556.
Externí odkaz:
https://www.jstor.org/stable/1621641
Autor:
Fukata, Yuko, Oshiro, Noriko, Kinoshita, Nagatoki, Kawano, Yoji, Matsuoka, Yoichiro, Bennett, Vann, Matsuura, Yoshiharu, Kaibuchi, Kozo
Publikováno v:
The Journal of Cell Biology, 1999 Apr . 145(2), 347-361.
Externí odkaz:
https://www.jstor.org/stable/1619270
MYO6 Regulates Spatial Organization of Signaling Endosomes Driving AKT Activation and Actin Dynamics
Publikováno v:
Cell Reports, Vol 19, Iss 10, Pp 2088-2101 (2017)
APPL1- and RAB5-positive signaling endosomes play a crucial role in the activation of AKT in response to extracellular stimuli. Myosin VI (MYO6) and two of its cargo adaptor proteins, GIPC and TOM1/TOM1L2, localize to these peripheral endosomes and m
Externí odkaz:
https://doaj.org/article/f33ebf36f3844a7db12a9ad1e1d7cd85
Publikováno v:
Membranes, Vol 10, Iss 8, p 177 (2020)
Macropinocytosis is a unique pathway of endocytosis characterised by the nonspecific internalisation of large amounts of extracellular fluid, solutes and membrane in large endocytic vesicles known as macropinosomes. Macropinocytosis is important in a
Externí odkaz:
https://doaj.org/article/1b6a2ada580d4ab0ab4fffc2f7cc5be9
Publikováno v:
Journal of the American Chemical Society
Intracellular pH (pHi) dynamics are critical for regulating normal cell physiology. For example, transient increases in pHi (7.2-7.6) regulate cell behaviors like cell polarization, actin cytoskeleton remodeling, and cell migration. Most studies on p
Autor:
Shiroh Futaki, Yusuke Hirai, Takahiro Iwata, Kentarou Sakamoto, Jan Vincent V. Arafiles, Hisaaki Hirose, Misao Akishiba, Miki Imanishi
Publikováno v:
Angewandte Chemie. 133:19957-19965
Fc region binding peptide conjugated with attenuated cationic amphiphilic lytic peptide L17E trimer [FcB(L17E)₃] was designed for immunoglobulin G (IgG) delivery into cells. Particle-like liquid droplets were generated by mixing Alexa Fluor 488 lab
Autor:
Lu Zhou, Lijun Liang, Luanluan Zhong, Shuyun Lin, Changcheng Yang, Xiaoping Liang, Chengjie Zhuo, Zhen Guo, Juan Yu, Ping Chen, Ying Wang, Peng Jiang, Mei Wang, Yu Chen
Publikováno v:
Cytoskeleton. 78:337-348
Membrane ruffling plays an important role in the directed cell migration and escape of tumor cells from the monolayer. Metastasis suppressor 1 (MTSS1), also known as missing in metastasis, has been implicated in cell morphology, motility, metastasis,