Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Quantification and visualization of phosphoinositides by quantum dot-labeled specific binding-domain probes

Autor: Yasuhiro Irino, Emi Tokuda, Junya Hasegawa, Toshiki Itoh, Tadaomi Takenawa

Publikováno v: Journal of Lipid Research, Vol 53, Iss 4, Pp 810-819 (2012)

Phosphoinositides (PI) play important regulatory roles in cell physiology. Localization and quantitation of PIs within the cell is necessary to understand their precise function. Currently, ectopic expression of green fluorescent protein (GFP)-fused

Externí odkaz: https://doaj.org/article/fda1723c2b3441d5bc8a2eb0f5bfb5b6

A signalling cascade involving receptor-activated phospholipase A2, glycerophosphoinositol 4-phosphate, Shp1 and Src in the activation of cell motility

Autor: Antonio Varriale, Vincenzo Maione, Maria Frucci, Mariangela Vessichelli, Fabio Formiggini, Matteo Lo Monte, Angela Flagiello, Daniela Spano, Daniela Corda, Stefania Mariggiò, Piero Pucci, Alessia Varone, Sabato D'Auria, Carmen Valente, Clara Iannuzzi, Pompea Del Vecchio, Nadia Brancati, Lucia Banci, Alberto Luini, Manpreet Patheja

Publikováno v: Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-21 (2019)
Cell communication and signaling 17 (2019). doi:10.1186/s12964-019-0329-3
info:cnr-pdr/source/autori:Varone A., Mariggiò S., Patheja M., Maione V., Varriale A., Vessichelli M., Spano D., Formiggini F., Lo Monte M., Brancati N., Frucci M., Del Vecchio P., D'Auria S., Flagiello A., Iannuzzi C., Luini A., Pucci P., Banci L., Valente C., and Corda D./titolo:A signalling cascade involving receptor-activated phospholipase A2, glycerophosphoinositol 4-phosphate, Shp1 and Src in the activation of cell motility/doi:10.1186%2Fs12964-019-0329-3/rivista:Cell communication and signaling/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:17

Background: Shp1, a tyrosine-phosphatase-1 containing the Src-homology 2 (SH2) domain, is involved in inflammatory and immune reactions, where it regulates diverse signalling pathways, usually by limiting cell responses through dephosphorylation of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ef9f3a2a55dfa9023818306b7ae338
http://link.springer.com/article/10.1186/s12964-019-0329-3

Correlative Fluorescence- and Electron Microscopy of Whole Breast Cancer Cells Reveals Different Distribution of ErbB2 Dependent on Underlying Actin

Autor: Niels de Jonge, Patrick Trampert, Zahra Mostajeran, Indra N. Dahmke, Florian Weinberg, Franziska Lautenschläger

Publikováno v: Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)

Epidermal growth factor receptor 2 (ErbB2) is found overexpressed in several cancers, such as gastric, and breast cancer, and is, therefore, an important therapeutic target. ErbB2 plays a central role in cancer cell invasiveness, and is associated wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959a8ad78bb15819fa9e9d08e8119508
https://pubmed.ncbi.nlm.nih.gov/32714928

A tent pole twist on membrane ruffles

Autor: Rene E. Harrison, Reuben Philip

Publikováno v: The Journal of Cell Biology

Condon et al. use lattice light-sheet microscopy to analyze live macrophages and define a new model of macropinosome formation and closure through tent pole ruffles. The ruffles, which are enhanced by LPS and regulated by Rab13, are erected and suppo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b357e6020a4d53faccd9fab635ab215
https://pubmed.ncbi.nlm.nih.gov/30150290