Zobrazeno 1 - 10
of 267
pro vyhledávání: '"membrane bilayer"'
Autor:
Stéphane Téletchéa, Jérémy Esque, Aurélie Urbain, Catherine Etchebest, Alexandre G. de Brevern
Publikováno v:
BioMedInformatics, Vol 3, Iss 2, Pp 306-326 (2023)
Transmembrane proteins (TMPs) are a class of essential proteins for biological and therapeutic purposes. Despite an increasing number of structures, the gap with the number of available sequences remains impressive. The choice of a dedicated function
Externí odkaz:
https://doaj.org/article/0229553b59f842e4a4f6396501008586
Publikováno v:
Biophysica, Vol 3, Iss 2, Pp 263-275 (2023)
In our previous studies, a new opioid (NFEPP) was developed to only selectively bind to the μ-opoid receptor (MOR) in inflamed tissue and thus avoid the severe side effects of fentanyl. We know that NFEPP has a reduced binding affinity to MOR in hea
Externí odkaz:
https://doaj.org/article/ead5259faca148e7aab3c0f1eef5a318
Autor:
Alexey Lukin, Anna Bakholdina, Mikhail Chudinov, Oleksandra Onopchenko, Elena Zhuravel, Sergey Zozulya, Maxim Gureev, Mikhail Krasavin
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1650-1657 (2021)
A set of 1,3,4-thiadiazole-2-carboxamides bearing a substituted biphenyl in the amide portion was synthesised and tested for agonistic activity towards free fatty acid receptor 1 (FFA1). The observed activity trends were impossible to rationalised ba
Externí odkaz:
https://doaj.org/article/9d3f63a014b74b7099392ec6f9080af1
Autor:
Kristen A. Johnson, Nisha Bhattarai, Melissa R. Budicini, Carolyn M. LaBonia, Sarah Catherine B. Baker, Bernard S. Gerstman, Prem P. Chapagain, Robert V. Stahelin
Publikováno v:
Viruses, Vol 13, Iss 7, p 1375 (2021)
Ebolavirus (EBOV) is a negative-sense RNA virus that causes severe hemorrhagic fever in humans. The matrix protein VP40 facilitates viral budding by binding to lipids in the host cell plasma membrane and driving the formation of filamentous, pleomorp
Externí odkaz:
https://doaj.org/article/aa3d0b2cb2cf43b2a24ac1e035e12cb8
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4598
International Journal of Molecular Sciences, 24 (5)
Volume 24
Issue 5
Pages: 4598
International Journal of Molecular Sciences, 24 (5)
Protein kinase C delta (PKC-δ) is an important signaling molecule in human cells that has both proapoptotic as well as antiapoptotic functions. These conflicting activities can be modulated by two classes of ligands, phorbol esters and bryostatins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf428056bf2345aa750d428f33605b0
Autor:
Olga E. Glukhova
Publikováno v:
Molecules, Vol 25, Iss 8, p 1875 (2020)
This paper discusses specific features of the interactions of small-diameter liposomes with the cytoplasmic membrane of endothelial cells using in silico methods. The movement pattern of the liposomal drug delivery system was modeled in accordance wi
Externí odkaz:
https://doaj.org/article/f0c7dea9e8ba4a158c7840b432855cbf
Akademický článek
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Publikováno v:
Journal of Lipid Research, Vol 56, Iss 11, Pp 2151-2157 (2015)
Type IV P-type ATPases (P4-ATPases) translocate phospholipids from the exoplasmic to the cytoplasmic leaflets of cellular membranes. We and others previously showed that ATP11C, a member of the P4-ATPases, translocates phosphatidylserine (PS) at the
Externí odkaz:
https://doaj.org/article/3edb34ab83a7419390c6936b225ed45d
Akademický článek
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Akademický článek
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