Zobrazeno 1 - 10
of 44
pro vyhledávání: '"mehrdad zarei"'
Autor:
Ali Vaziri-Gohar, Jonathan J. Hue, Ata Abbas, Hallie J. Graor, Omid Hajihassani, Mehrdad Zarei, George Titomihelakis, John Feczko, Moeez Rathore, Sylwia Chelstowska, Alexander W. Loftus, Rui Wang, Mahsa Zarei, Maryam Goudarzi, Renliang Zhang, Belinda Willard, Li Zhang, Adam Kresak, Joseph E. Willis, Gi-Ming Wang, Curtis Tatsuoka, Joseph M. Salvino, Ilya Bederman, Henri Brunengraber, Costas A. Lyssiotis, Jonathan R. Brody, Jordan M. Winter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Pancreatic Ductal Adenocarcinoma (PDAC) is highly resistant to chemotherapy. Effective alternative therapies have yet to emerge, as chemotherapy remains the best available systemic treatment. However, the discovery of safe and available adju
Externí odkaz:
https://doaj.org/article/d2faef86ea85483498c70286f6d2ac00
Autor:
Mehrdad Zarei, Omid Hajihassani, Jonathan J. Hue, Hallie J. Graor, Alexander W. Loftus, Moeez Rathore, Ali Vaziri-Gohar, John M. Asara, Jordan M. Winter, Luke D. Rothermel
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Alternative treatment strategies in melanoma beyond immunotherapy and mutation-targeted therapy are urgently needed. Wild-type isocitrate dehydrogenase 1 (wtIDH1) has recently been implicated as a metabolic dependency in cancer. T
Externí odkaz:
https://doaj.org/article/81d5fbf1b7e24bb7b6768e02fe81e9ba
Autor:
mehrdad zarei
Publikováno v:
فصلنامه نقد ادبی, Vol 15, Iss 57, Pp 111-146 (2022)
In any scientific research, the research method is the main factor in obtaining accurate and correct results. Therefore, researchers in various fields of science try to conduct their research within the framework of methods defined in their disciplin
Externí odkaz:
https://doaj.org/article/ebe25cce9de8487d86b68b2ef47d9151
Autor:
Mehrdad Zarei, Effat Neghabi
Publikováno v:
نثرپژوهی ادب فارسی, Vol 23, Iss 47, Pp 75-100 (2020)
Carikalamature, is simple, short, and literary sentence which evoke a caricaturelike humorous image. Some researchers view this as a byproduct of getting in contact with western literature through translation Whereas this kind of short, thematic pros
Externí odkaz:
https://doaj.org/article/7eb19d1bb6f845618af0e5c6408b7ce8
Autor:
Pooja Acharya, Parvati Huded, Sadashivaiah Bettadahalli, Mehrdad Zarei, Vinayak Uppin, Nayana Venugopal, Ramaprasad Ravichandra Talahalli
Publikováno v:
Journal of Agriculture and Food Research, Vol 2, Iss , Pp 100035- (2020)
Hyperlipidemia is a metabolic abnormality in both young and aged populations across the world. Withaferin-A (WT) present in Withania somnifera (Indian ginseng) has been studied by many investigators for their therapeutic potentials. However, their ef
Externí odkaz:
https://doaj.org/article/be1eef719afd4f1eb0aa6ac67f29b608
Autor:
Jonathan J. Hue, Hallie J. Graor, Mehrdad Zarei, Erryk S. Katayama, Karen Ji, Omid Hajihassani, Alexander W. Loftus, Ali Vaziri-Gohar, Jordan M. Winter
Publikováno v:
Molecular Cancer Therapeutics. 21:1810-1822
Metabolites of tryptophan degradation are known to alter mood. Their effects have only been superficially examined in the context of pancreatic cancer. Herein, we study the role of indoleamine 2,3-dioxygenase 1 (IDO1), an enzyme important in the conv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156e3c30b09a1e96551c8251808f6d66
https://doi.org/10.1158/1535-7163.mct-22-0055
https://doi.org/10.1158/1535-7163.mct-22-0055
Autor:
Jordan M. Winter, Ali Vaziri-Gohar, Alexander W. Loftus, Omid Hajihassani, Karen Ji, Erryk S. Katayama, Mehrdad Zarei, Hallie J. Graor, Jonathan J. Hue
Supplementary Figure from IDO1 Is a Therapeutic Target for Pancreatic Cancer–Associated Depression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f759fa9037486b80e0e4fb4a91717b
https://doi.org/10.1158/1535-7163.22523701.v1
https://doi.org/10.1158/1535-7163.22523701.v1
Autor:
Ali Vaziri-Gohar, Joel Cassel, Farheen S. Mohammed, Mehrdad Zarei, Jonathan J. Hue, Omid Hajihassani, Hallie J. Graor, Yellamelli V. V. Srikanth, Saadia A. Karim, Ata Abbas, Erin Prendergast, Vanessa Chen, Erryk S. Katayama, Katerina Dukleska, Imran Khokhar, Anthony Andren, Li Zhang, Chunying Wu, Bernadette Erokwu, Chris A. Flask, Mahsa Zarei, Rui Wang, Luke D. Rothermel, Andrea M. P. Romani, Jessica Bowers, Robert Getts, Curtis Tatsuoka, Jennifer P. Morton, Ilya Bederman, Henri Brunengraber, Costas A. Lyssiotis, Joseph M. Salvino, Jonathan R. Brody, Jordan M. Winter
Publikováno v:
Nature Cancer. 3:852-865
Nutrient-deprived conditions in the tumor microenvironment (TME) restrain cancer cell viability due to increased free radicals and reduced energy production. In pancreatic cancer cells a cytosolic metabolic enzyme, wild-type isocitrate dehydrogenase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3094737c279b470283468552b409050b
https://doi.org/10.1038/s43018-022-00393-y
https://doi.org/10.1038/s43018-022-00393-y
Surgical techniques and tips for a reliable murine model of primary and metastatic pancreatic cancer
Autor:
Jonathan J. Hue, Mehrdad Zarei, Hallie J. Graor, Omid Hajihassani, Erryk S. Katayama, Alexander W. Loftus, Ali Vaziri-Gohar, Jordan M. Winter
For patients with pancreatic cancer, survival rates lag behind other common cancers. This is in part due to the relative resistance to conventional chemotherapeutics and novel immune- or targeted-therapies. Ongoing research efforts are needed to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8043347c29ea697379eec8be75b6b19b
https://doi.org/10.1101/2022.07.30.502136
https://doi.org/10.1101/2022.07.30.502136
Publikováno v:
Life Sciences. 320:121563
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d419442dbc0ba20569cfc9df80a224d
https://doi.org/10.1016/j.lfs.2023.121563
https://doi.org/10.1016/j.lfs.2023.121563