Zobrazeno 1 - 10
of 1 491
pro vyhledávání: '"mechanosensitivity"'
Autor:
Anastasiia A. Latypova, Alexey V. Yaremenko, Nadezhda A. Pechnikova, Artem S. Minin, Ilya V. Zubarev
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-26 (2024)
Abstract Magnetogenetics emerges as a transformative approach for modulating cellular signaling pathways through the strategic application of magnetic fields and nanoparticles. This technique leverages the unique properties of magnetic nanoparticles
Externí odkaz:
https://doaj.org/article/cbd5d26d99794bb482b4c24c630af53b
Autor:
Bavat Bornstein, Bridgette Watkins, Fabian S. Passini, Ronen Blecher, Eran Assaraf, Xiao Meng Sui, Vlad Brumfeld, Michael Tsoory, Stephan Kröger, Elazar Zelzer
Publikováno v:
Experimental Physiology, Vol 109, Iss 1, Pp 135-147 (2024)
Abstract By translating mechanical forces into molecular signals, proprioceptive neurons provide the CNS with information on muscle length and tension, which is necessary to control posture and movement. However, the identities of the molecular playe
Externí odkaz:
https://doaj.org/article/b43a8c871e8844cdb58d0c72dac21ca5
Autor:
Dilara Yılmaz, Francisco C. Marques, Yannick Fischer, Sandra Zimmermann, Gaonhae Hwang, Penny R. Atkins, Neashan Mathavan, Amit Singh, Pedro P.C. de Souza, Gisela A. Kuhn, Esther Wehrle, Ralph Müller
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32949- (2024)
Osteoclasts are essential for bone remodeling by adapting their resorptive activity in response to their mechanical in vivo environment. However, the molecular mechanisms underlying this process remain unclear. Here, we demonstrated the role of tartr
Externí odkaz:
https://doaj.org/article/2c19d0aea6ad4f23b8eb6ead6fd3d6a9
Autor:
Valentin Ruffine, Andreas Hartmann, Annika Frenzel, Michael Schlierf, Elisabeth Fischer‐Friedrich
Publikováno v:
Advanced Physics Research, Vol 2, Iss 12, Pp n/a-n/a (2023)
Abstract The actin cortex is an active polymer network underneath the plasma membrane at the periphery of mammalian cells. It is a major regulator of cell shape through the generation of active cortical tension. In addition, the cortex constitutes a
Externí odkaz:
https://doaj.org/article/f70e73e9f57b4c28aaead8603f3ea3bc
Publikováno v:
Mathematical Biosciences and Engineering, Vol 20, Iss 2, Pp 2408-2438 (2023)
Mechanosensitivity of cell spread area to substrate stiffness has been established both through experiments and different types of mathematical models of varying complexity including both the mechanics and biochemical reactions in the cell. What has
Externí odkaz:
https://doaj.org/article/a46709e48df34c6aa985ab6d4163f0af
Autor:
Hodan Ibrahim, Kevin Retailleau, Fraser Hornby, Jacquie Maignel, Matthew Beard, Donna Marie Daly
Publikováno v:
Toxins, Vol 16, Iss 1, p 30 (2024)
Botulinum neurotoxin A (BoNT/A) is a potent neurotoxin that silences cholinergic neurotransmission through the cleavage of the synaptic protein SNAP-25. Previous studies have shown that, in addition to its paralytic effects, BoNT/A can inhibit sensor
Externí odkaz:
https://doaj.org/article/539d303bc0134f4480d60c956db88901
Akademický článek
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Autor:
Misty M. Strain, Sirima Tongkhuya, Nathan Wienandt, Farah Alsadoon, Roger Chavez, Jamar Daniels, Thomas Garza, Alex V. Trevino, Kenney Wells, Thomas Stark, John Clifford, Natasha M. Sosanya
Publikováno v:
BMC Neuroscience, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract In the military, constant physiological and psychological stress encountered by Soldiers can lead to development of the combat and operational stress reaction (COSR), which can effect pain management. Similar effects are seen in other popula
Externí odkaz:
https://doaj.org/article/cc081f3c7fc94c4eb1af11a3dbd46ebc
Publikováno v:
Royal Society Open Science, Vol 10, Iss 5 (2023)
In this work, we report investigations of the swimming behaviour of Paramecium tetraurelia, a unicellular microorganism, in micro-engineered pools that are decorated with thousands of cylindrical pillars. Two types of contact interactions are measure
Externí odkaz:
https://doaj.org/article/8ab41efcb1c34162b536fb3757f4c1e9
Autor:
Alberto Montaner-Cuello, Elena Bueno-Gracia, Diego Rodríguez-Mena, Elena Estébanez-de-Miguel, Miguel Malo-Urriés, Gianluca Ciuffreda, Santos Caudevilla-Polo
Publikováno v:
Healthcare, Vol 11, Iss 24, p 3138 (2023)
The straight leg raise test (SLR) has been proposed to detect increased nerve mechanosensitivity of the lower limbs in individuals with low back pain. However, its validity in the diagnosis of lumbosacral radiculopathy shows very variable results. Th
Externí odkaz:
https://doaj.org/article/96e50f6dd91244509f3690adf2db1199