Zobrazeno 1 - 10
of 2 042
pro vyhledávání: '"mavs"'
Autor:
Olivia Luise Gern, Andreas Pavlou, Felix Mulenge, Lena Mareike Busker, Luca Ghita, Angela Aringo, Bibiana Costa, Julia Spanier, Inken Waltl, Martin Stangel, Ulrich Kalinke
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Viral encephalitis is characterized by a series of immunological reactions that can control virus infection in the brain, but dysregulated responses may cause excessive inflammation and brain damage. Microglia are brain-resident myeloid cell
Externí odkaz:
https://doaj.org/article/3a4b81cf883c496bbc455a39ca77bc0f
Publikováno v:
Journal of Applied Fluid Mechanics, Vol 17, Iss 12, Pp 2579-2591 (2024)
The current study analyzed the piezoelectrically driven mechanism responsible for generating force in both rectangular and hummingbird wings, which mimicked the flapping motion of the micro air vehicles, utilizing a combination of numerical simulatio
Externí odkaz:
https://doaj.org/article/0977c460f3d6420e985d7f5bf48b0739
Autor:
Wu Chengyue, Wang Mengdong, Wang Xiaoquan, Chen Yeping, Li Hao, Sun Liumei, Ren Jianle, Zhang Zhendong
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-14 (2024)
Abstract Pseudorabies virus (PRV) has evolved multiple strategies to evade host antiviral responses to benefit virus replication and establish persistent infection. Recently, tripartite motif 26 (TRIM26), a TRIM family protein, has been shown to be i
Externí odkaz:
https://doaj.org/article/54742877b13047138a1beee05bebbdce
Autor:
Jiyu Zhang, Liaoyuan Zhang, Dakai Liu, Hongyan Shi, Xin Zhang, Jianfei Chen, Xiaoman Yang, Miaomiao Zeng, Jialin Zhang, Tingshuai Feng, Xiaoyuan Zhu, Zhaoyang Jing, Zhaoyang Ji, Da Shi, Li Feng
Publikováno v:
mBio, Vol 15, Iss 12 (2024)
ABSTRACT Type Ι interferon (IFN) production mediated by retinoic acid-inducible gene 1 (RIG-I) and mitochondrial antiviral signaling protein (MAVS) is essential for antiviral innate immune responses. Here, we report the identification of a novel co-
Externí odkaz:
https://doaj.org/article/59d110772ddb4ab8a965bfa598779162
Publikováno v:
Autophagy Reports, Vol 3, Iss 1 (2024)
Pseudorabies virus (PRV) poses a significant threat to the global swine industry, characterized by high morbidity and a range of sequelae in infected pigs. Mitochondria serve as a crucial platform for innate immunity, playing a pivotal role in a wide
Externí odkaz:
https://doaj.org/article/bfc2195aa1084edaadf66e478e9ef05a
Publikováno v:
Virus Research, Vol 350, Iss , Pp 199498- (2024)
Zinc finger proteins (ZFPs) play an important role in the host-virus interplay. Zinc finger protein 36 is a member of the zinc finger protein 36 family, which includes two other paralogs, namely ZFP36L1 and ZFP36L2. Studies have demonstrated that ZFP
Externí odkaz:
https://doaj.org/article/c6817aebccb04db391aed6dc7ca34083
Autor:
Aotian Ouyang, Tong Chen, Yi Feng, Jiahui Zou, Shaoyu Tu, Meijun Jiang, Huimin Sun, Hongbo Zhou
Publikováno v:
Advanced Science, Vol 11, Iss 39, Pp n/a-n/a (2024)
Abstract Ferroptosis is a novel form of cell death caused by the accumulation of lipid peroxides in an iron‐dependent manner. However, the precise mechanism underlying the exploitation of ferroptosis by influenza A viruses (IAV) remains unclear. Th
Externí odkaz:
https://doaj.org/article/7694253653ff4155b78f0bee2a042452
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/7218cbcb0fb74bb6a485ecd884e3648d
Autor:
Jiawei Luo, Yiyuan Lu, Enqi Dai, Nianchun Yin, Ting Wang, Hongxi Qian, Qingrong Jiang, Xin Cao, Chunfeng Wang, Yan Zeng
Publikováno v:
Poultry Science, Vol 104, Iss 1, Pp 104639- (2025)
The proteins encoded by Influenza A virus (IAV) evade the innate immune system through diverse strategies to facilitate their replication. However, the regulatory mechanisms remain not fully understood. In this study, we identified that the H9N2 PB1
Externí odkaz:
https://doaj.org/article/bd1f9665257f42a0a214094f349b8a1a
Autor:
Tinghui Huang, Xudong Ao, Jie Liu, Chuancheng Sun, Yunfei Dong, Xuechen Yin, Yan Zhang, Xinping Wang, Wenying Li, Jiujiu Cao, Feiyan Pan, Zhigang Hu, Zhigang Guo, Lingfeng He
Publikováno v:
Translational Oncology, Vol 51, Iss , Pp 102230- (2025)
Our experimental study showed that METTL3 was highly expressed in NSCLC cells and promoted the growth of tumor cells. METTL3 takes N6-methyladenosine (m6A) as the main means of mRNA modification to control the expression and function of RIG-I-MAVS si
Externí odkaz:
https://doaj.org/article/6e2a23b1017742e1ad5b2a37310d080f