Zobrazeno 1 - 10
of 248
pro vyhledávání: '"matrix vesicle"'
Autor:
Tomoka Hasegawa, Hiromi Hongo, Tomomaya Yamamoto, Takafumi Muneyama, Yukina Miyamoto, Norio Amizuka
Publikováno v:
Endocrines, Vol 4, Iss 1, Pp 66-81 (2023)
Finely tuned cartilage mineralization, endochondral ossification, and normal bone formation are necessary for normal bone growth. Hypertrophic chondrocytes in the epiphyseal cartilage secrete matrix vesicles, which are small extracellular vesicles in
Externí odkaz:
https://doaj.org/article/e8847149932548cbb9a2c25a3db7759e
Publikováno v:
Medicine in Novel Technology and Devices, Vol 17, Iss , Pp 100198- (2023)
As the quality of life improves, people pay more and more attention to health. They are concerned about the causes of diseases, and seek better treatments. The most common diseases are biomineralized diseases, four different kinds of typical examples
Externí odkaz:
https://doaj.org/article/31f21889d68d4df7a44eac4150e302e4
Publikováno v:
Biology, Vol 12, Iss 1, p 110 (2023)
Extracellular vesicles (EVs) are cell-derived membrane-surrounded vesicles carrying various types of molecules. These EV cargoes are often used as pathophysiological biomarkers and delivered to recipient cells whose fates are often altered in local a
Externí odkaz:
https://doaj.org/article/25ab865ffad348e88be31ee4c12b076a
Autor:
Heitor Gobbi Sebinelli, Luiz Henrique Silva Andrilli, Bruno Zoccaratto Favarin, Marcos Aantonio Eufrasio Cruz, Maytê Bolean, Michele Fiore, Carolina Chieffo, David Magne, Andrea Magrini, Ana Paula Ramos, José Luis Millán, Saida Mebarek, Rene Buchet, Massimo Bottini, Pietro Ciancaglini
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15072 (2022)
Matrix vesicles (MVs) contain the whole machinery necessary to initiate apatite formation in their lumen. We suspected that, in addition to tissue-nonspecific alkaline phosphatase (TNAP), Na,K,-ATPase (NKA) could be involved in supplying phopshate (P
Externí odkaz:
https://doaj.org/article/467255f218c0437bbed1431e476b680a
Akademický článek
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Autor:
Tomoka Hasegawa, Hiromi Hongo, Tomomaya Yamamoto, Miki Abe, Hirona Yoshino, Mai Haraguchi-Kitakamae, Hotaka Ishizu, Tomohiro Shimizu, Norimasa Iwasaki, Norio Amizuka
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9941 (2022)
Bone mineralization entails two mineralization phases: primary and secondary mineralization. Primary mineralization is achieved when matrix vesicles are secreted by osteoblasts, and thereafter, bone mineral density gradually increases during secondar
Externí odkaz:
https://doaj.org/article/34e33ea4087641768fd7c77e8a1f5567
Autor:
Ekeveliny Amabile Veschi, Maytê Bolean, Luiz Henrique da Silva Andrilli, Heitor Gobbi Sebinelli, Agnieszka Strzelecka-Kiliszek, Joanna Bandorowicz-Pikula, Slawomir Pikula, Thierry Granjon, Saida Mebarek, David Magne, José Luis Millán, Ana Paula Ramos, Rene Buchet, Massimo Bottini, Pietro Ciancaglini
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 8945 (2022)
The biochemical machinery involved in matrix vesicles-mediated bone mineralization involves a specific set of lipids, enzymes, and proteins. Annexins, among their many functions, have been described as responsible for the formation and stabilization
Externí odkaz:
https://doaj.org/article/efab12b628004f9194511f536812b39e
Autor:
Scott Dillon, Karla Suchacki, Shun‐Neng Hsu, Louise A Stephen, Rongling Wang, William P Cawthorn, Alan J Stewart, Fabio Nudelman, Nicholas M Morton, Colin Farquharson
Publikováno v:
JBMR Plus, Vol 5, Iss 2, Pp n/a-n/a (2021)
ABSTRACT Biomineralization is a fundamental process key to the development of the skeleton. The phosphatase orphan phosphatase 1 (PHOSPHO1), which likely functions within extracellular matrix vesicles, has emerged as a critical regulator of biominera
Externí odkaz:
https://doaj.org/article/a5a5889ab84443e18ecd1ba4f5fff0b4
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 12060 (2021)
Sphingosine-1-phosphate receptor 2 (S1PR2) is a G protein-coupled receptor that regulates various immune responses. Herein, we determine the effects of a S1PR2 antagonist (JTE013) or a S1PR2 shRNA on osteogenesis by culturing murine bone marrow strom
Externí odkaz:
https://doaj.org/article/28f43dc6f0ea46f0a3b480db16276085
Autor:
Tomoka Hasegawa, DDS, Ph.D, Tomomaya Yamamoto, Erika Tsuchiya, Hiromi Hongo, Kanako Tsuboi, Ai Kudo, Miki Abe, Taiji Yoshida, Tomoya Nagai, Naznin Khadiza, Ayako Yokoyama, Kimimitsu Oda, Hidehiro Ozawa, Paulo Henrique Luiz de Freitas, Minqi Li, Norio Amizuka
Publikováno v:
Japanese Dental Science Review, Vol 53, Iss 2, Pp 34-45 (2017)
Matrix vesicle-mediated mineralization is an orchestrated sequence of ultrastructural and biochemical events that lead to crystal nucleation and growth. The influx of phosphate ions into the matrix vesicle is mediated by several proteins such as TNAP
Externí odkaz:
https://doaj.org/article/eaf689f038fe4089a44dd0a95d389400