Zobrazeno 1 - 10
of 150
pro vyhledávání: '"mass cytometry (CyTOF)"'
Autor:
Sturla M. Grøndal, Magnus Blø, Linn I. H. Nilsson, Austin J. Rayford, Akil Jackson, Gro Gausdal, James B. Lorens
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe incidence of chronic kidney disease (CKD) is increasing, in parallel with risk factors including obesity and diabetes mellitus. AXL plays a central role in CKD, providing a rationale to evaluate clinical AXL targeting agents.MethodsTo
Externí odkaz:
https://doaj.org/article/fb0ccd45b79b4d14af7b2e872d22b624
Autor:
Nan Shao, Chenshuo Ren, Tianyuan Hu, Dianbing Wang, Xiaofan Zhu, Min Li, Tao Cheng, Yingchi Zhang, Xian-En Zhang
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-20 (2023)
Abstract Background Acute myeloid leukaemia (AML) is characterised by the malignant accumulation of myeloid progenitors with a high recurrence rate after chemotherapy. Blasts (leukaemia cells) exhibit a complete myeloid differentiation hierarchy hidi
Externí odkaz:
https://doaj.org/article/d0b7353eb9f34c9db8be013bdc62389d
Autor:
Adrian Gihring, Fabian Gärtner, Laura Mayer, Aileen Roth, Hend Abdelrasoul, Marko Kornmann, Leonard Elad, Uwe Knippschild
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionObesity is associated with low-grade chronic inflammation, altered levels of adipocytokines, and impaired regulation of gastrointestinal hormones. Secreted, these factors exert immunostimulatory functions directly influencing peripheral i
Externí odkaz:
https://doaj.org/article/492ce8d922654dfd87eefb99e512958d
Autor:
Kentaro Hata, Toyoshi Yanagihara, Keisuke Matsubara, Kazufumi Kunimura, Kunihiro Suzuki, Kazuya Tsubouchi, Daisuke Eto, Hiroyuki Ando, Maki Uehara, Satoshi Ikegame, Yoshihiro Baba, Yoshinori Fukui, Isamu Okamoto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Immune cells have been implicated in interstitial lung diseases (ILDs), although their phenotypes and effector mechanisms remain poorly understood. To better understand these cells, we conducted an exploratory mass cytometry analysis of immune cell s
Externí odkaz:
https://doaj.org/article/3f14ccfe44594d7d82573bf50619bd88
Autor:
Eva Castellano, Célia Samba, Gloria Esteso, Laura Simpson, Elena Vendrame, Eva M. García‐Cuesta, Sheila López‐Cobo, Mario Álvarez-Maestro, Ana Linares, Asier Leibar, Thanmayi Ranganath, Hugh T. Reyburn, Luis Martínez‐Piñeiro, Catherine Blish, Mar Valés‐Gómez
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
High grade non-muscle-invasive bladder tumours are treated with transurethral resection followed by recurrent intravesical instillations of Bacillus Calmette Guérin (BCG). Although most bladder cancer patients respond well to BCG, there is no clinic
Externí odkaz:
https://doaj.org/article/86d96bbb33ea4821b94baed32ef23626
Autor:
Irene Sarkar, Richard Davies, Anders K. Aarebrot, Silje M. Solberg, Aleksandra Petrovic, Anagha M. Joshi, Brith Bergum, Johan G. Brun, Daniel Hammenfors, Roland Jonsson, Silke Appel
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPrimary Sjögren’s syndrome (pSS) is a systemic autoimmune disease, characterized by mononuclear cell infiltrates in the salivary and lacrimal glands, leading to glandular atrophy and dryness. Patient heterogeneity and lack of knowledge r
Externí odkaz:
https://doaj.org/article/74b26a25e51e4a9c94addbf117df9014
Autor:
Zheng Yan, Holden T. Maecker, Petter Brodin, Unni C. Nygaard, Shu Chen Lyu, Mark M. Davis, Kari C. Nadeau, Sandra Andorf
Publikováno v:
Immunity & Ageing, Vol 18, Iss 1, Pp 1-12 (2021)
Abstract Background Broadly, much of variance in immune system phenotype has been linked to the influence of non-heritable factors rather than genetics. In particular, two non-heritable factors: aging and human cytolomegavirus (CMV) infection, have b
Externí odkaz:
https://doaj.org/article/1ee23ef593d442e79fbb86656f0f3b13
Autor:
Carole Chedid, Thibault Andrieu, Eka Kokhreidze, Nestani Tukvadze, Samanta Biswas, Md. Fahim Ather, Mohammad Khaja Mafij Uddin, Sayera Banu, Flavio De Maio, Giovanni Delogu, Hubert Endtz, Delia Goletti, Marc Vocanson, Oana Dumitrescu, Jonathan Hoffmann, Florence Ader
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Tuberculosis (TB) is a difficult-to-treat infection because of multidrug regimen requirements based on drug susceptibility profiles and treatment observance issues. TB cure is defined by mycobacterial sterilization, technically complex to systematica
Externí odkaz:
https://doaj.org/article/c6fef1411b6d41fd90e06d1208c65839
Autor:
Erin M. Wilfong, Todd Bartkowiak, Katherine N. Vowell, Camille S. Westlake, Jonathan M. Irish, Peggy L. Kendall, Leslie J. Crofford, Rachel H. Bonami
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The idiopathic inflammatory myopathies (IIM) are a rare clinically heterogeneous group of conditions affecting the skin, muscle, joint, and lung in various combinations. While myositis specific autoantibodies are well described, we postulate that bro
Externí odkaz:
https://doaj.org/article/a5d1bd4e467f4ee99deded0e6ec3f6eb
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Antigen-specific immunotherapy is an appealing strategy to preserve beta-cell function in type 1 diabetes, although the approach has yet to meet its therapeutic endpoint. Direct administration of autoantigen into lymph nodes has emerged as an alterna
Externí odkaz:
https://doaj.org/article/99dd57ea8f8148d39f1b7fbb089923e5