Zobrazeno 1 - 10
of 54
pro vyhledávání: '"marzieh dehghan shasaltaneh"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Many of plant proteins exhibit the properties similar to the antitumor proteins although the anticancer activity of Brazzein on modulating the autophagy signaling pathway has not been determined so far. The present study aimed to develop a s
Externí odkaz:
https://doaj.org/article/c28e082a1d124e4c9925a6ffe54f7d9c
Autor:
Zhangqiang Xiang, Xiangyu Deng, Wenfeng He, Qian Yang, Laichao Ni, Marzieh Dehghan Shasaltaneh, Mazaher Maghsoudloo, Gang Yang, Jingbo Wu, Saber Imani, Qinglian Wen
Publikováno v:
Annals of Medicine, Vol 54, Iss 1, Pp 1357-1371 (2022)
Background Vascular endothelial growth factor (VEGF) is a critical regulator of malignant pleural effusion (MPE) in non-small-cell lung cancer (NSCLC). Bevacizumab (BEV) and apatinib (APA) are novel VEGF blockers that inhibit lung cancer cell prolife
Externí odkaz:
https://doaj.org/article/ee982b8fae30485b9cdd6579c7e25f48
Publikováno v:
Cell Journal, Vol 24, Iss 3, Pp 105-111 (2022)
Objective: Change in astrocytes is one of the first pathological symptoms of Alzheimer’s disease (AD). Understanding the signaling pathways in astrocytes can be a great help in treating of AD. This study aimed to investigate signaling pathway relat
Externí odkaz:
https://doaj.org/article/cfd53327dab14f23b795f4efc81000e6
Autor:
Wenqiong Ma, Zexiu Wu, Mazaher Maghsoudloo, Iqra Ijaz, Marzieh Dehghan Shasaltaneh, Yuqin Zhang, Qiao Weng, Junjiang Fu, Saber Imani, Qing Lian Wen
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0285806 (2023)
To discover vulnerabilities associated with dermokine (DMKN) as a new trigger of the epithelial-mesenchymal transition (EMT) -driven melanoma, we undertook a genome-wide genetic screening using transgenic. Here, we showed that DMKN expression could b
Externí odkaz:
https://doaj.org/article/d9acfd359c354bb6a50f3ac9a9087ab1
Autor:
Gang Yang, Shuya Liu, Mazaher Maghsoudloo, Marzieh Dehghan Shasaltaneh, Parham Jabbarzadeh Kaboli, Cuiwei Zhang, Youcai Deng, Hajar Heidari, Maliheh Entezari, ShaoZhi Fu, QingLian Wen, Saber Imani
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract BRAF and NRAS are the most reported mutations associated to melanomagenesis. The lack of accurate diagnostic markers in response to therapeutic treatment in BRAF/NRAS-driven melanomagenesis is one of the main challenges in melanoma personali
Externí odkaz:
https://doaj.org/article/dcfc640f6f074ff08497882c637ba4bf
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The adenylate cyclase (ADCY) superfamily is a group of glycoproteins regulating intracellular signaling. ADCYs act as key regulators in the cyclic adenosine monophosphate (cAMP) signaling pathway and are related to cell sensitivity to chemotherapy an
Externí odkaz:
https://doaj.org/article/9422cd16cb7c455fb3d9317cb8369090
Publikováno v:
Iranian Biomedical Journal, Vol 24, Iss 2, Pp 64-80 (2020)
Aging, as a major risk factor of memory deficiency, affects neural signaling pathways in hippocampus. In particular, age-dependent androgens deficiency causes cognitive impairments. Several enzymes like PKC are involved in memory deficiency. Indeed,
Externí odkaz:
https://doaj.org/article/8917d5be964141e5b472b8d0c41866cd
Autor:
WenFeng He, Gang Yang, Shuya Liu, Mazaher Maghsoudloo, Marzieh Dehghan Shasaltaneh, Parham Jabbarzadeh Kaboli, Cuiwei Zhang, JingHeng Zhang, Maliheh Entezari, Saber Imani, QingLian Wen
Publikováno v:
Translational Oncology, Vol 14, Iss 12, Pp 101237- (2021)
This study aimed to identify a novel disease-associated differentially co-expressed mRNA-microRNA (miRNA) that is associated with vasculogenic mimicry (VM) and epithelial-to-mesenchymal transition (EMT) network at different stages of melanoma. By app
Externí odkaz:
https://doaj.org/article/cd749398646545d1bceb2854a836125d
Autor:
Sara Amiri, Kayhan Azadmaneshb, Marzieh Dehghan Shasaltaneh, Baharak Khoshkholgh-Sima, Nasser Naghdi
Publikováno v:
Basic and Clinical Neuroscience, Vol 10, Iss 6, Pp 545-556 (2019)
Introduction: Alzheimer disease (AD) is a neurodegenerative disorder characterized by the progressive loss of memory and other cognitive functions. Protein kinase Cε (PKCε) is an isoform that most effectively suppresses amyloid beta (Aβ) productio
Externí odkaz:
https://doaj.org/article/029a5f76b9a8453b8bc29815008c1f8e
Autor:
Zhenhua Zhang, Saber Imani, Marzieh Dehghan Shasaltaneh, Hossein Hosseinifard, Linglin Zou, Yu Fan, Qinglian Wen
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Vasculogenic mimicry (VM) a microvascular system consisting of non-endothelial cells that is newly formed by aggressive tumors, has been proposed as an important therapeutic target in malignant melanoma (MM). We performed a system
Externí odkaz:
https://doaj.org/article/e96781a43b7d40658fc3649475223f2d