Zobrazeno 1 - 10
of 52
pro vyhledávání: '"marian kalocsay"'
Autor:
Katherine J. Susa, Gary A. Bradshaw, Robyn J. Eisert, Charlotte M. Schilling, Marian Kalocsay, Stephen C. Blacklow, Andrew C. Kruse
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114332- (2024)
Summary: The B cell receptor (BCR) signals together with a multi-component co-receptor complex to initiate B cell activation in response to antigen binding. Here, we take advantage of peroxidase-catalyzed proximity labeling combined with quantitative
Externí odkaz:
https://doaj.org/article/1216f0b2527b47618886cbc540d72911
Autor:
Marian Kalocsay, Matthew J. Berberich, Robert A. Everley, Maulik K. Nariya, Mirra Chung, Benjamin Gaudio, Chiara Victor, Gary A. Bradshaw, Robyn J. Eisert, Marc Hafner, Peter K. Sorger, Caitlin E. Mills, Kartik Subramanian
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-9 (2023)
Abstract We performed quantitative proteomics on 60 human-derived breast cancer cell line models to a depth of ~13,000 proteins. The resulting high-throughput datasets were assessed for quality and reproducibility. We used the datasets to identify an
Externí odkaz:
https://doaj.org/article/d36f69bd2a254d5687bc8e7f98e95fc1
Autor:
Cameron S. Fraser, Johan K. E. Spetz, Xingping Qin, Adam Presser, Jonathan Choiniere, Chendi Li, Stacey Yu, Frances Blevins, Aaron N. Hata, Jeffrey W. Miller, Gary A. Bradshaw, Marian Kalocsay, Vaishali Sanchorawala, Shayna Sarosiek, Kristopher A. Sarosiek
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Immunoglobulin light chain amyloidosis is a lethal hematologic disorder driven by clonal plasma cells producing abnormal light chains that damage healthy tissues. Fraser et al. show that BH3 mimetics, which inhibit pro-survival proteins BCL-2 or MCL-
Externí odkaz:
https://doaj.org/article/af565676a38f48089f10fb446aad1c14
Autor:
Alba Jiménez, Dan Lu, Marian Kalocsay, Matthew J Berberich, Petra Balbi, Ashwini Jambhekar, Galit Lahav
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 3, Pp 1-18 (2022)
Abstract The cell stress‐responsive transcription factor p53 influences the expression of its target genes and subsequent cellular responses based in part on its dynamics (changes in level over time). The mechanisms decoding p53 dynamics into subse
Externí odkaz:
https://doaj.org/article/c1c9a8215f07411f822a4bb11aeab073
Autor:
Elizabeth Mittendorf, Jennifer Guerriero, Peter Sorger, Nadine Tung, Anita Mehta, Emily Cheney, Christina Hartl, Constantia Pantelidou, Madison Oliwa, Jessica Castrillon, Jia-Ren Lin, Mateus de Oliveira Taveira, Nathan Johnson, William Oldham, Marian Kalocsay, Matthew Berberich, Sarah Boswell, Aditi Kothari, Shawn Johnson, Deborah Dillon, Mikel Lipschitz, Scott Rodig, Sandro Santagata, Judy Garber, José Yélamos, Geoffrey Shapiro
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/bf791cf00da94f9eac81dac39c1b962d
Publikováno v:
eLife, Vol 9 (2020)
Heterochromatic domains containing histone H3 lysine 9 methylation (H3K9me) can be epigenetically inherited independently of underlying DNA sequence. To gain insight into the mechanisms that mediate epigenetic inheritance, we used a Schizosaccharomyc
Externí odkaz:
https://doaj.org/article/81905807a78d47b6ae44e1920d3ae94d
Autor:
Douaa Mugahid, Marian Kalocsay, Xili Liu, Jonathan Scott Gruver, Leonid Peshkin, Marc W Kirschner
Publikováno v:
eLife, Vol 9 (2020)
The Hippo pathway regulates organ size, regeneration, and cell growth by controlling the stability of the transcription factor, YAP (Yorkie in Drosophila). When there is tissue damage, YAP is activated allowing the restoration of homeostatic tissue s
Externí odkaz:
https://doaj.org/article/5ba2af129bfc4e7c9cff75ede41cbfcf
Autor:
Arianne Papa, Sergey I. Zakharov, Alexander N. Katchman, Jared S. Kushner, Bi-xing Chen, Lin Yang, Guoxia Liu, Alejandro Sanchez Jimenez, Robyn J. Eisert, Gary A. Bradshaw, Wen Dun, Shah R. Ali, Aaron Rodriques, Karen Zhou, Veli Topkara, Mu Yang, John P. Morrow, Emily J. Tsai, Arthur Karlin, Elaine Wan, Marian Kalocsay, Geoffrey S. Pitt, Henry M. Colecraft, Manu Ben-Johny, Steven O. Marx
Publikováno v:
Nature Cardiovascular Research. 1:1022-1038
Fight-or-flight responses involve β-adrenergic-induced increases in heart rate and contractile force. In the present study, we uncover the primary mechanism underlying the heart’s innate contractile reserve. We show that four protein kinase A (PKA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d29a7152c7195aa5159ea1ac39befef0
https://doi.org/10.1038/s44161-022-00157-y
https://doi.org/10.1038/s44161-022-00157-y
Autor:
Mengying Zhou, Rui Fang, Louis Colson, Katherine Donovan, Moritz Hunkeler, Siyi Chen, Yuyu Song, Can Zhang, Dong-hoon Lee, Gary Bradshaw, Robyn Eisert, Yihong Ye, Marian Kalocsay, Alfred Goldberg, Eric S Fischer, Ying Lu
Publikováno v:
bioRxiv
Selective breakdown of proteins and aggregates is crucial for maintaining normal cellular activities and is involved in the pathogenesis of diverse diseases. How the cell recognizes and tags these targets in different structural states for degradatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1dba68e169e00542e70ec131c16553
https://europepmc.org/articles/PMC10312588/
https://europepmc.org/articles/PMC10312588/
Autor:
Arianne, Papa, Sergey I, Zakharov, Alexander N, Katchman, Jared S, Kushner, Bi-Xing, Chen, Lin, Yang, Guoxia, Liu, Alejandro Sanchez, Jimenez, Robyn J, Eisert, Gary A, Bradshaw, Wen, Dun, Shah R, Ali, Aaron, Rodriques, Karen, Zhou, Veli, Topkara, Mu, Yang, John P, Morrow, Emily J, Tsai, Arthur, Karlin, Elaine, Wan, Marian, Kalocsay, Geoffrey S, Pitt, Henry M, Colecraft, Manu, Ben-Johny, Steven O, Marx
Publikováno v:
Nature cardiovascular research. 1(11)
Fight-or-flight responses involve β-adrenergic-induced increases in heart rate and contractile force. In the present study, we uncover the primary mechanism underlying the heart's innate contractile reserve. We show that four protein kinase A (PKA)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::098eb2ff6d51588c62d0ba69760229f2
https://pubmed.ncbi.nlm.nih.gov/36424916
https://pubmed.ncbi.nlm.nih.gov/36424916