Zobrazeno 1 - 10
of 29
pro vyhledávání: '"marcos DeLima"'
Autor:
Muhammad Salman Faisal, Walter Hanel, Timothy Voorhees, Rui Li, Ying Huang, Abdullah Khan, David Bond, Yazeed Sawalha, John Reneau, Lapo Alinari, Robert Baiocchi, Beth Christian, Kami Maddocks, Yvonne Efebera, Sam Penza, Ayman Saad, Jonathan Brammer, Marcos DeLima, Samantha Jaglowski, Narendranath Epperla
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 8228-8237 (2023)
Abstract Background Relapsed or refractory Hodgkin lymphoma (R/R HL) is a challenging disease with limited treatment options beyond brentuximab vedotin and checkpoint inhibitors. Herein we present the time‐trend analysis of R/R HL patients who rece
Externí odkaz:
https://doaj.org/article/383fe9a36f884222a6f100a5694522a7
Autor:
Avirup Guha, Prantesh Jain, Michael G. Fradley, Daniel Lenihan, Jahir M. Gutierrez, Chhavi Jain, Marcos deLima, Jill S. Barnholtz‐Sloan, Guilherme H. Oliveira, Afshin Dowlati, Sadeer Al‐Kindi
Publikováno v:
Cancer Medicine, Vol 10, Iss 12, Pp 3862-3872 (2021)
Abstract Background Cardiovascular adverse events (CVAEs) associated with BRAF inhibitors alone versus combination BRAF/MEK inhibitors are not fully understood. Methods This study included all adult patients who received BRAF inhibitors (vemurafenib,
Externí odkaz:
https://doaj.org/article/7d4bbd84fa12427dbc25a5c503168be7
Autor:
Reshmi Parameswaran, Parameswaran Ramakrishnan, Stephen A. Moreton, Zhiqiang Xia, Yongchun Hou, Dean A. Lee, Kalpana Gupta, Marcos deLima, Rose C. Beck, David N. Wald
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Natural killer cells of acute myeloid leukaemia patients lack cytotoxic activity. Here the authors show that these cells have elevated GSK3β, and that its inhibition prolongs survival of mice transplanted with human AML and stimulates NK cytotoxicit
Externí odkaz:
https://doaj.org/article/e1e049514d104978859f1c4b3b7f9b43
Autor:
Brittany Knick Ragon, Mithun Vinod Shah, Anita D'Souza, Noel Estrada-Merly, Lohith Gowda, Gemlyn George, marcos DeLima, Shahrukh Hashmi, Mohamed A Kharfan-Dabaja, Navneet S Majhail, Rahul Banerjee, Ayman Saad, Gerhard C. Hildebrandt, Hira Mian, Muhammad Bilal Abid, Minoo Battiwalla, Lazaros J. Lekakis, Sagar S. Patel, Hemant S. Murthy, Yago Nieto, Christopher S Strouse, Sherif M. Badawy, Samer AI Al Hadidi, Bhagirathbhai Dholaria, Mahmoud Aljurf, David H Vesole, Cindy H Lee, Attaphol Pawarode, Usama Gergis, Kevin Charles Miller, Leona A Holmberg, Aimaz Afrough, Melhem M Solh, Pashna Munshi, Taiga Nishihori, Larry D. Anderson, Baldeep Wirk, Gurbakhash Kaur, Muzaffar H Qazilbash, Nina Shah, Shaji K Kumar, Saad Z. Usmani
Publikováno v:
Blood Advances.
The overall survival (OS) has improved significantly in multiple myeloma (MM) over the last decade with use of proteasome inhibitor and immunomodulatory drug-based combinations, followed by high-dose melphalan and autologous hematopoietic stem cell t
Autor:
Sadeer G. Al-Kindi, Isaac B Rhea, Amit K. Dey, Avirup Guha, Guilherme H. Oliveira, Marcos deLima
Publikováno v:
Bone Marrow Transplantation. 56:544-551
The purpose of this review is to provide a framework for the cardiovascular evaluation and management of patients undergoing hematopoietic cell transplantation (HCT). To accomplish this, we have performed an extensive literature review, critically an
Autor:
Evi X. Stavrou, David N. Wald, Mieko Matsuyama, Steve Horvath, Kyuhyeon Kim, Arne Søraas, Shigemi Matsuyama, John Arne Dahl, Marcos deLima, Paolo Caimi, Sarah Yu
Publikováno v:
Experimental Biology and Medicine. 245:1543-1551
The mechanism of aging is not yet fully understood. It has been recognized that there are age-dependent changes in the DNA methylation pattern of the whole genome. To date, there are several DNA methylation-based estimators of the chronological age.
Autor:
Mieko, Matsuyama, Arne, Søraas, Sarah, Yu, Kyuhyeon, Kim, Evi X, Stavrou, Paolo F, Caimi, David, Wald, Marcos, deLima, John A, Dahl, Steve, Horvath, Shigemi, Matsuyama
Publikováno v:
Exp Biol Med (Maywood)
The mechanism of aging is not yet fully understood. It has been recognized that there are age-dependent changes in the DNA methylation pattern of the whole genome. To date, there are several DNA methylation-based estimators of the chronological age.
Autor:
Nausheen Ahmed, Sumanth Khadke, Shine Raju, M. Rizwan Sohail, Ratts, Marcos deLima, Nayla Ahmed, Gallogly, Molly PhD, Ryan PhD
Publikováno v:
SSRN Electronic Journal.
Background: Coronavirus Disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, previously named 2019-nCov), a novel coronavirus that emerged in China in December 2019 and was declared a global pandemic by Wo
Autor:
Madan Jagasia, Veronika Bachanova, Khoan Vu, Betty K. Hamilton, Christopher R. Flowers, Dennis Dong Hwan Kim, Steven M. Devine, Auro Viswabandya, Anjali S. Advani, Melody Smith, Rizwan Romee, Siddharth Ganguly, Karamjeet S. Sandhu, Miguel-Angel Perales, Joseph P. McGuirk, Donna Abounader, Lisa Rybicki, Kehinde Adekola, Simon B. Zeichner, Stacey Brown, Sarah A Wall, Navneet S. Majhail, Vinod Pullarkat, Ibrahim Aldoss, Masumi Ueda, Vanessa E Kennedy, Asad Bashey, Marcos deLima
Publikováno v:
Biology of Blood and Marrow Transplantation. 23:1117-1121
Allogeneic hematopoietic cell transplantation (HCT) is recommended for patients with T cell acute lymphoblastic leukemia (T-ALL) in second or later complete remission (CR) and high-risk patients in first CR. Given its relative rarity, data on outcome
Autor:
Marcos deLima, Parameswaran Ramakrishnan, Dean A. Lee, Kalpana Gupta, Reshmi Parameswaran, Rose Beck, Yongchun Hou, David N. Wald, Stephen Moreton, Zhiqiang Xia
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications
Nature Communications
Natural killer cells from acute myeloid leukaemia patients (AML-NK) show a dramatic impairment in cytotoxic activity. The exact reasons for this dysfunction are not fully understood. Here we show that the glycogen synthase kinase beta (GSK3β) expres