Topical Amphotericin B Semisolid Dosage Form for Cutaneous Leishmaniasis: Physicochemical Characterization, Ex Vivo Skin Permeation and Biological Activity

Autor: Diana Berenguer, Maria Magdalena Alcover, Marcella Sessa, Lyda Halbaut, Carme Guillén, Antoni Boix-Montañés, Roser Fisa, Ana Cristina Calpena-Campmany, Cristina Riera, Lilian Sosa

Publikováno v: Pharmaceutics, Vol 12, Iss 2, p 149 (2020)

Amphotericin B (AmB) is a potent antifungal successfully used intravenously to treat visceral leishmaniasis but depending on the Leishmania infecting species, it is not always recommended against cutaneous leishmaniasis (CL). To address the need for

Externí odkaz: https://doaj.org/article/07458a352c3d42a9949dd10bf0f9a637

An application of the Toronto Childhood Cancer Stage Guidelines in three population‐based cancer registries: The case of central nervous tumors

Autor: Sabrina Fabiano, Gemma Gatta, Daniela Alessi, Milena Maule, Fabio Savoia, Giovanna Tagliabue, Anna D’Agostino, Francesco Vetrano, Carlotta Sacerdote, Franco Merletti, Patrizia Piga, Marcella Sessa, Maria Luisa Mosso

Publikováno v: Pediatric Blood & Cancer. 67

Background Cancer stage is a determinant of survival of childhood central nervous system (CNS) cancers and could help the interpretation of survival variability among countries. Consensus guidelines to stage childhood malignancies in population cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456160cbfcda3e6d9f9ff89e3d81ae28
https://doi.org/10.1002/pbc.28303

Development and Characterization of a Semi-Solid Dosage Form of Meglumine Antimoniate for Topical Treatment of Cutaneous Leishmaniasis

Autor: Roser Fisa, Carme Guillén, Diana Berenguer, Ana C. Calpena-Campmany, Magdalena Alcover, Lyda Halbaut, Lilian Sosa, Marcella Sessa, Cristina Riera

Publikováno v: Pharmaceutics, Vol 11, Iss 11, p 613 (2019)
Pharmaceutics
Volume 11
Issue 11
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona

Cutaneous leishmaniasis (CL) is treated with painful intralesional injections of meglumine antimoniate (MA). With the aim of developing an alternative topical treatment for CL, a gel-based formulation with 30% MA was prepared and its physicochemical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1d978cb324147135ff3ea5f652b80b
http://hdl.handle.net/2445/146042

Unraveling framework of the ancestral Mediator complex in human diseases

Autor: Amelia Casamassimi, Teresa Infante, Claudio Napoli, Marcella Sessa

Publikováno v: Biochimie. 94:579-587

Mediator (MED) is a fundamental component of the RNA polymerase II-mediated transcription machinery. This multiprotein complex plays a pivotal role in the regulation of eukaryotic mRNA synthesis. The yeast Mediator complex consists of 26 different su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839090ed8c490b4c77c98454cbce8fce
https://doi.org/10.1016/j.biochi.2011.09.016

Glycoxydation promotes vascular damage Via MAPK-ERK/JNK pathways

Autor: Claudio Napoli, Louis J. Ignarro, Elena Cesario, Wulf Palinski, Antonio Giordano, Teresa Infante, Mohammed Al-Omran, Filomena de Nigris, Monica Rienzo, Marcella Sessa

Oxidation and glycation enhance foam cell formation via MAPK/JNK in euglycemic and diabetic subjects. Here, we investigated the effects of glycated and oxidized LDL (glc-oxLDL) on MAPK-ERK and JNK signaling pathways using human coronary smooth muscle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2aa19dfd97185a7b9ae66152be793c
http://hdl.handle.net/11365/1129641