Defining key roles for auxiliary proteins in an ABC transporter that maintains bacterial outer membrane lipid asymmetry

Autor: Shuhua Thong, Bilge Ercan, Federico Torta, Zhen Yang Fong, Hui Yi Alvina Wong, Markus R Wenk, Shu-Sin Chng

Publikováno v: eLife, Vol 5 (2016)

In Gram-negative bacteria, lipid asymmetry is critical for the function of the outer membrane (OM) as a selective permeability barrier, but how it is established and maintained is poorly understood. Here, we characterize a non-canonical ATP-binding c

Externí odkaz: https://doaj.org/article/87d1edefc7ac45a7a79c7381ce7c05fa

Defining key roles for auxiliary proteins in an ABC transporter that maintains bacterial outer membrane lipid asymmetry.

Autor: Thong S; Department of Chemistry, National University of Singapore, Singapore, Singapore., Ercan B; Department of Chemistry, National University of Singapore, Singapore, Singapore., Torta F; Department of Biochemistry, National University of Singapore, Singapore, Singapore., Fong ZY; Department of Chemistry, National University of Singapore, Singapore, Singapore., Wong HY; Department of Chemistry, National University of Singapore, Singapore, Singapore., Wenk MR; Department of Biochemistry, National University of Singapore, Singapore, Singapore., Chng SS; Department of Chemistry, National University of Singapore, Singapore, Singapore.; Singapore Center on Environmental Life Sciences Engineering, National University of Singapore, Singapore, Singapore.

Publikováno v: ELife [Elife] 2016 Aug 16; Vol. 5. Date of Electronic Publication: 2016 Aug 16.